Corticosteroid metabolism in isolated rat kidney in vitro

1984 ◽  
Vol 400 (4) ◽  
pp. 377-380 ◽  
Author(s):  
G. -A. Hoyer ◽  
D. Tsiakiras ◽  
H. Siebe ◽  
K. Hierholzer
Keyword(s):  
Rat Kidney ◽  
Isolated Rat Kidney ◽  
Isolated Rat

scholarly journals In vitro metabolism of 25-hydroxyvitamin D3 by isolated rat kidney cells

1980 ◽  
Vol 77 (3) ◽  
pp. 1537-1540 ◽  
Author(s):  
R. T. Turner ◽  
B. L. Bottemiller ◽  
G. A. Howard ◽  
D. J. Baylink
Keyword(s):  
Rat Kidney ◽  
In Vitro Metabolism ◽  
Kidney Cells ◽  
Isolated Rat Kidney ◽  
Isolated Rat

Stimulatory action of parathyroid hormone on renin secretion in vitro: a study using isolated rat kidney, isolated rabbit glomeruli and superfused dispersed rat juxtaglomerular cells

1993 ◽  
Vol 84 (1) ◽  
pp. 11-19 ◽  
Author(s):  
Christian Saussine ◽  
C. Judes ◽  
T. Massfelder ◽  
M.-J. Musso ◽  
U. Simeoni ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Rat Kidney ◽  
Renin Secretion ◽  
Renin Release ◽  
Juxtaglomerular Cells ◽  
Isolated Kidney ◽  
Stimulatory Action ◽  
Isolated Rat Kidney ◽  
Isolated Rat

1. We have previously reported that pharmacological concentrations (125 nmol/l) of parathyroid hormone may stimulate renin release in the stable recirculating and non-filtering isolated rat kidney. 2. In the present study we have attempted to extend these initial observations by examining the concentration-related response of renin release to parathyroid hormone, using the same model of isolated kidney, and determining whether the effect of parathyroid hormone on renin release can be demonstrated by more direct approaches. Thus, the effects of parathyroid hormone on renin secretion were investigated in two other renal preparations: isolated rabbit glomeruli and isolated rat juxtaglomerular cells. 3. In the isolated kidney, rat parathyroid hormone significantly stimulated renin accumulation in the perfusate in a concentration-related manner with a threshold of 1 nmol/l. 4. In both glomeruli and juxtaglomerular cells bovine [Nle8,18,Tyr34]parathyroid hormone-(1–34)amide effectively and repeatedly stimulated renin release. These results imply that there is a direct stimulatory effect of parathyroid hormone on renin release. 5. We also examined the effect of [Nle8,18, Tyr34]parathyroid hormone-(l-34)amide during extracellular calcium buffering in the glomeruli. [Nle8,18,Tyr34]parathyroid hormone-(1–34)amide was uneffective in calcium-free medium. Increasing the extracellular ionized calcium concentration to 2.5 mmol/l increased the extent of stimulation in accordance with the reported ability of parathyroid hormone to block calcium channels and relax vascular smooth muscle cells. 6. These results provide further support for the role of parathyroid hormone as a direct mediator of renin secretion; moreover, the renin-stimulating action of parathyroid hormone may be mediated through the inhibition of calcium influx.s

Corticosteroid metabolism in isolated rat kidney in vitro

1984 ◽  
Vol 400 (4) ◽  
pp. 363-371 ◽  
Author(s):  
K. Hierholzer ◽  
M. Sch�nesh�fer ◽  
H. Siebe ◽  
D. Tsiakiras ◽  
P. Weskamp ◽  
...  
Keyword(s):  
Rat Kidney ◽  
Isolated Rat Kidney ◽  
Isolated Rat

Corticosteroid metabolism in isolated rat kidney in vitro

1984 ◽  
Vol 400 (4) ◽  
pp. 372-376 ◽  
Author(s):  
H. Siebe ◽  
D. Tsiakiras ◽  
K. Hierholzer ◽  
Lichtenstein
Keyword(s):  
Rat Kidney ◽  
Isolated Rat Kidney ◽  
Isolated Rat

Characterization of Ascorbic Acid Uptake by Isolated Rat Kidney Cells

1991 ◽  
Vol 121 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Delores M. Bowers-Komro ◽  
Donald B. McCormick
Keyword(s):  
Ascorbic Acid ◽  
Rat Kidney ◽  
Acid Uptake ◽  
Kidney Cells ◽  
Isolated Rat Kidney ◽  
Isolated Rat

Toxicity of depleted uranium on isolated rat kidney mitochondria

2012 ◽  
Vol 1820 (12) ◽  
pp. 1940-1950 ◽  
Author(s):  
Fatemeh Shaki ◽  
Mir-Jamal Hosseini ◽  
Mahmoud Ghazi-Khansari ◽  
Jalal Pourahmad
Keyword(s):  
Rat Kidney ◽  
Depleted Uranium ◽  
Kidney Mitochondria ◽  
Isolated Rat Kidney ◽  
Isolated Rat
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