Does tissue ATP content limit active sodium transport across intestinal epithelia in vitro?

1982 ◽  
Vol 395 (3) ◽  
pp. 257-259 ◽  
Author(s):  
Markus Grasl ◽  
Peter Krivanek ◽  
Klaus Turnheim
1977 ◽  
Vol 37 (1) ◽  
pp. 63-84 ◽  
Author(s):  
Klaus Turnheim ◽  
Raymond A. Frizzell ◽  
Stanley G. Schultz

Author(s):  
Paula T. Beall ◽  
Karl J. Karnaky ◽  
Leon T. Garretson ◽  
Yuh-Jyh Kuo ◽  
Linda L. Shanbour

1964 ◽  
Vol 47 (3) ◽  
pp. 419-432 ◽  
Author(s):  
Jean Crabbé

ABSTRACT Aldosterone can stimulate the active transport of sodium by the isolated toad bladder in vitro. Corticosterone, cortisol, 17β-oestradiol and progesterone had no such effect despite incubation of the preparation with more than 100 times the smallest effective concentration of aldosterone. When the serosal surface of the membranes was exposed to 10 μg% d-aldosterone combined with 100 times this concentration of corticosterone, cortisol or progesterone, the stimulating action of aldosterone was reduced. Spirolactone SC 9420 failed to exert by itself a significant effect on the isolated toad bladder in vitro, but this compound blocked the stimulation by aldosterone of active sodium transport in vitro when present at concentrations 50 times those of aldosterone. When the concentration ratio was 10:1, a hormonal effect could be demonstrated, except at the highest concentration of the drug used.


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