Thoracic duct lymph flow and composition in conscious dogs and the influence of anaesthesia and passive limb movement

1977 ◽  
Vol 371 (1-2) ◽  
pp. 25-31 ◽  
Author(s):  
H. Schad ◽  
H. Brechtelsbauer
Keyword(s):  
Thoracic Duct ◽  
Limb Movement ◽  
Lymph Flow ◽  
Conscious Dogs ◽  
Thoracic Duct Lymph ◽  
Duct Lymph

scholarly journals Lymphatic Pump Treatment Increases Thoracic Duct Lymph Flow in Conscious Dogs with Edema Due to Constriction of the Inferior Vena Cava

2010 ◽  
Vol 8 (3) ◽  
pp. 149-154 ◽  
Author(s):  
Parna Prajapati ◽  
Pankhil Shah ◽  
Hollis H. King ◽  
Arthur G. Williams ◽  
Pratikkumar Desai ◽  
...  
Keyword(s):  
Inferior Vena Cava ◽  
Thoracic Duct ◽  
Inferior Vena ◽  
Vena Cava ◽  
Lymph Flow ◽  
Conscious Dogs ◽  
Thoracic Duct Lymph ◽  
Lymphatic Pump Treatment ◽  
Duct Lymph

scholarly journals Lymphatic Pump Treatment Increases Thoracic Duct Lymph Flow in Conscious Dogs with Edema Due to Constriction of the Inferior Vena Cava

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Parna Ramprasad Prajapati ◽  
Pankhil Virenkumar Shah ◽  
Hollis H. King ◽  
Arthur G. Williams ◽  
Pratikkumar Vrajeshbhai Desai ◽  
...  
Keyword(s):  
Inferior Vena Cava ◽  
Thoracic Duct ◽  
Inferior Vena ◽  
Vena Cava ◽  
Lymph Flow ◽  
Conscious Dogs ◽  
Thoracic Duct Lymph ◽  
Lymphatic Pump Treatment ◽  
Duct Lymph

Thoracic duct lymph flow during head-out water immersion in conscious dogs

1987 ◽  
Vol 252 (4) ◽  
pp. R782-R785
Author(s):  
K. Miki ◽  
M. M. Pazik ◽  
E. Krasney ◽  
S. K. Hong ◽  
J. A. Krasney
Keyword(s):  
Thoracic Duct ◽  
Water Immersion ◽  
Mean Value ◽  
Lymph Flow ◽  
Urine Flow ◽  
Conscious Dogs ◽  
Thoracic Duct Lymph ◽  
Fluid Shift ◽  
Maximum Value ◽  
Duct Lymph

Water immersion (WI) increases plasma volume in awake dogs. The contribution of lymph flow to this fluid shift was studied in six splenectomized conscious dogs with a side fistula of the thoracic duct. Lymph flow, hematocrit (Hct), and plasma (CP) and lymph (CL) protein concentration were measured during 60 min in air and 120 min of WI (37 degrees C). Lymph flow in air averaged 0.96 +/- 1.0 (SE) ml/min. Lymph flow tended to decrease immediately in WI and was maintained at a level averaging 0.66 ml/min. CP/CL did not change significantly, whereas Hct fell significantly by 1.51 +/- 0.2% (Hct units) at 40 min of WI. Urine flow increased significantly to a maximum value of 1.5 +/- 0.5 ml/min at 40-60 min of WI compared with a mean value in air of 0.3 +/- 0.1 ml/min. The Hct and urine flow responses indicate that fluid shifted into the intravascular space during WI. Since lymph flow tended to decrease, the fluid shift in WI occurs across the capillary wall and not via lymphatic channels.

Effect of PEEP on the rate of thoracic duct lymph flow and clearance of bacteria from the peritoneal cavity

1983 ◽  
Vol 145 (1) ◽  
pp. 126-130 ◽  
Author(s):  
Michael Last ◽  
Lewis Kurtz ◽  
Theodore A. Stein ◽  
Leslie Wise
Keyword(s):  
Peritoneal Cavity ◽  
Thoracic Duct ◽  
Lymph Flow ◽  
Thoracic Duct Lymph ◽  
Duct Lymph

Thoracic duct lymph flow and its measurement in chronically catheterized sheep fetus

1989 ◽  
Vol 256 (1) ◽  
pp. H16-H20 ◽  
Author(s):  
R. A. Brace
Keyword(s):  
Flow Rate ◽  
Thoracic Duct ◽  
Lymphatic Vessels ◽  
Lymph Flow ◽  
Thoracic Duct Lymph ◽  
Computer Technique ◽  
Venous Circulation ◽  
Duct Lymph ◽  
Unit Body Weight ◽  
Sheep Fetus

A method was developed for chronic catheterization of the left thoracic lymph duct at the base of the neck in the sheep fetus, which did not disrupt the other major lymphatic vessels that join the venous circulation at the same location. The lymphatic catheter was connected to a catheter in a jugular vein when lymph flow was not being recorded, so that the lymph continuously returned to the fetal circulation. Special consideration of catheter size to minimize flow resistance and treatment to prevent clotting were required. Individual animals were maintained up to 17 days with lymph flow continuing. In 13 fetuses averaging 128 days gestation (term = 147 days) at the time of catheterization, lymph flow rate was measured for 1 h each day for the first 7 postsurgical days with an on-line computer technique that continuously calculated lymph flow rate. Lymph flow averaged 0.64 +/- 0.17 (SD) ml/min in fetuses weighing 2.3-4 kg and tended to undergo a nonsignificant increase with time. Lymph and plasma protein concentrations did not change with time. In individual fetuses, large spontaneous variations in lymph flow rate occurred over periods of several seconds to a few minutes. Analysis showed that these variations in flow rate were not associated with fetal breathing movements. Thus the present study describes a technique for studying the dynamics of lymph flow in the unanesthetized sheep fetus in utero over a time period limited primarily by the length of gestation. In addition, it appears that thoracic duct lymph flow rate in the fetus per unit body weight averages three to four times that in the adult.

Chronic lymph flow and transcapillary fluid flux during angiotensin II hypertension

1990 ◽  
Vol 259 (6) ◽  
pp. R1205-R1213 ◽  
Author(s):  
J. Valenzuela-Rendon ◽  
R. D. Manning
Keyword(s):  
Angiotensin Ii ◽  
Plasma Protein ◽  
Thoracic Duct ◽  
Protein Transport ◽  
Lymph Flow ◽  
Fluid Volume ◽  
Thoracic Duct Lymph ◽  
Ang Ii ◽  
Fluid Flux ◽  
Duct Lymph

The roles of the transvascular fluid flux and lymph flow in the distribution of extracellular fluid volume during angiotensin II (ANG II) hypertension were evaluated in 11 conscious dogs. Similarly, the factors regulating the distribution of plasma protein across the microvasculature were assessed. By the second day of ANG II infusion, the thoracic duct lymph flow had increased 58% above control, transcapillary fluid flux had increased 45%, and plasma volume, sulfate space, and interstitial fluid volume remained close to control. In addition, the thoracic duct lymph protein transport had increased 34%, and the accompanying increase in transcapillary protein flux prevented any change in plasma protein mass. Also, at this time, the lymph flow and protein transport from subcutaneous tissue in the hind limb were not increased, and the permeability-surface area product of this region decreased 40%. The origin of the increased thoracic duct lymph flow on day 2 probably was from the splanchnic bed. In conclusion, the increased lymph flow during ANG II hypertension compensated for the increase in transcapillary fluid flux, thus preventing edema formation.

Thoracic duct lymph and lymphocytes during primary hypoxia and rebound

1965 ◽  
Vol 208 (6) ◽  
pp. 1243-1246 ◽  
Author(s):  
D. A. Evans ◽  
R. A. F. Garnett ◽  
J. M. Yoffey
Keyword(s):  
Control Animal ◽  
Thoracic Duct ◽  
Guinea Pigs ◽  
Control Level ◽  
Lymph Flow ◽  
Total Cell ◽  
Thoracic Duct Lymph ◽  
Simulated Altitude ◽  
Cell Content ◽  
Duct Lymph

Thoracic duct lymph flow and lymphocytes were first studied in 18 normal guinea pigs. Similar studies were then made on a) 25 guinea pigs placed in a decompression chamber at a simulated altitude of 14,000 ft for times ranging from 1 to 5 days, this being the period of "primary hypoxia" during which erythropoiesis is stimulated and polycythemia develops, and b) 25 guinea pigs exposed to primary hypoxia for 5 days, then kept in room air for times ranging from 1 to 5 days, this period of posthypoxic polycythemia being known as "rebound." By the end of rebound the polycythemia had almost disappeared. The flow of thoracic duct lymph increased significantly from a control level of 0.86 ± 0.21 ml/hr to 1.23 ± 0.1 ml/hr by the 5th day of primary hypoxia, and to a peak of 1.89 ± 0.23 ml/hr by the 3rd day of rebound, falling slightly to 1.56 ± 0.14 ml/hr by the 5th day of rebound, when it was still markedly above control level. The total cell content of the lymph also rose significantly, from 34.5 ± 10.3 x 106 lymphocytes/hr in the control animal to 59.1 ± 8.9 x 106 /hr on the 5th day of primary hypoxia, and to a peak of 93.8 ± 23.0 x 106 on the 3rd day of rebound.

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