Fibre type transition and stiffness modification of soleus muscle of trained rats

1987 ◽  
Vol 410 (3) ◽  
pp. 321-325 ◽  
Author(s):  
F. Goubel ◽  
J. F. Marini
Keyword(s):  
Soleus Muscle ◽  
Fibre Type ◽  
Type Transition

scholarly journals Nuclear factor E2-related factor 2 (NRF2) deficiency accelerates fast fibre type transition in soleus muscle during space flight

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Takuto Hayashi ◽  
Takashi Kudo ◽  
Ryo Fujita ◽  
Shin-ichiro Fujita ◽  
Hirona Tsubouchi ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Atrophy ◽  
Soleus Muscle ◽  
Space Flight ◽  
Skeletal Muscle Atrophy ◽  
Muscle Fibres ◽  
Type I ◽  
Muscle Plasticity ◽  
Type Transition

AbstractMicrogravity induces skeletal muscle atrophy, particularly in the soleus muscle, which is predominantly composed of slow-twitch myofibre (type I) and is sensitive to disuse. Muscle atrophy is commonly known to be associated with increased production of reactive oxygen species. However, the role of NRF2, a master regulator of antioxidative response, in skeletal muscle plasticity during microgravity-induced atrophy, is not known. To investigate the role of NRF2 in skeletal muscle within a microgravity environment, wild-type and Nrf2-knockout (KO) mice were housed in the International Space Station for 31 days. Gene expression and histological analyses demonstrated that, under microgravity conditions, the transition of type I (oxidative) muscle fibres to type IIa (glycolytic) was accelerated in Nrf2-KO mice without affecting skeletal muscle mass. Therefore, our results suggest that NRF2 affects myofibre type transition during space flight.

Influence of 12 weeks of hypobaric hypoxia on fibre type composition of the rat soleus muscle

1995 ◽  
Vol 154 (3) ◽  
pp. 417-418 ◽  
Author(s):  
K. ITOH ◽  
M. ITOH ◽  
A. ISHIHARA ◽  
C. HIROFUJI ◽  
H. HAYASHI
Keyword(s):  
Soleus Muscle ◽  
Fibre Type ◽  
Hypobaric Hypoxia ◽  
Fibre Type Composition ◽  
Type Composition ◽  
Rat Soleus Muscle
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