Biological monitoring of workers exposed toN,N-dimethylformamide by determination of the urinary metabolites,N-methylformamide andN-acetyl-S-(N-methylcarbamoyl) cysteine

1995 ◽  
Vol 67 (2) ◽  
pp. 125-129 ◽  
Author(s):  
Tadashi Sakai ◽  
Hiroshi Kageyama ◽  
Takaharu Araki ◽  
Takayuki Yosida ◽  
Takeshi Kuribayashi ◽  
...  
Keyword(s):  
Biological Monitoring ◽  
Urinary Metabolites

Simultaneous HPLC Determination of Urinary Metabolites of Toluene, Xylenes, and Ethylbenzene; and Its Application to Biological Monitoring of Tunisian Workers Exposure

2006 ◽  
Vol 39 (1) ◽  
pp. 83-97 ◽  
Author(s):  
Radhouane Chakroun ◽  
Abderrazek Hedhili ◽  
Fayçal Faidi ◽  
Habib Nouaigui ◽  
Mohamed Ben Laiba
Keyword(s):  
Biological Monitoring ◽  
Urinary Metabolites ◽  
Hplc Determination

scholarly journals Benzene, toluene, ethylbenzene, and xylene: Current analytical techniques and approaches for biological monitoring

2020 ◽  
Vol 39 (1) ◽  
pp. 168-187
Author(s):  
Esmaeel Soleimani
Keyword(s):  
Sample Preparation ◽  
Biological Monitoring ◽  
Analytical Methods ◽  
Analytical Techniques ◽  
Urinary Metabolites ◽  
Extraction Methods ◽  
Exhaled Air ◽  
Occupationally Exposed ◽  
Benzene Toluene

Abstract Benzene, toluene, ethylbenzene, and xylene (BTEX) are a group of volatile organic compounds that human exposure to them may result in the development of some diseases, including cancer. Biological monitoring plays an important role in exposure assessment of workers occupationally exposed to chemicals. Several metabolites have been proposed for biological monitoring of individuals who are exposed to BTEX. There are a variety of extraction methods and analytical techniques for the determination of unmetabolized BTEX in exhaled air and their urinary metabolites. The present study aimed to summarize and review the toxicokinetics of BTEX and sample preparation and analytical methods for their measurement. Metabolites of BTEX are discussed to find out reliable ones for biological monitoring of workers exposed to these chemicals. In addition, analytical methods for unmetabolized BTEX in exhaled air and their metabolites were reviewed in order to obtain a comparison between them in term of selectivity, sensitivity, simplicity, time, environmental-friendly and cost. Given the recent trends in sample preparation, including miniaturization, automation, high-throughput performance, and on-line coupling with analytical instrument, it seems that microextraction techniques, especially microextraction by packed sorbents are the methods of choice for the determination of the BTEX metabolites.

Studies on drug metabolism by use of isotopes XXVI: Determination of urinary metabolites of rutin in humans

1981 ◽  
Vol 70 (7) ◽  
pp. 780-782 ◽  
Author(s):  
Takashi Furuta ◽  
Masanobu Horie ◽  
Shigeo Baba ◽  
Hisashi Nakagawa
Keyword(s):  
Drug Metabolism ◽  
Urinary Metabolites
Sign in / Sign up

Export Citation Format

Share Document