Synthesis of derivatives of the androstane series. XXI. Synthesis and properties of some N-acylated androstano[3,2-c]pyrazoles

1981 ◽  
Vol 17 (1) ◽  
pp. 68-72
Author(s):  
L. N. Volovel'skii ◽  
N. M. Khvorova ◽  
I. I. Kuz'menko ◽  
S. N. Ushenko
Keyword(s):  
Androstane Series ◽  
Derivatives Of

Derivatives of the androstane series

1970 ◽  
Vol 6 (1) ◽  
pp. 28-29
Author(s):  
L. N. Volovel'skii ◽  
I. I. Kuz'menko
Keyword(s):  
Androstane Series ◽  
Derivatives Of

SYNTHESIS OF PYRAZOLINE AND ISOXAZOLINE DERIVATIVES OF ANDROSTANE SERIES

1993 ◽  
Vol 25 (3) ◽  
pp. 356-360 ◽  
Author(s):  
A. U. Siddiqui ◽  
D. Ramesh ◽  
Y. Satyanarayana ◽  
M. Srinivas ◽  
A. H. Siddiqui
Keyword(s):  
Androstane Series ◽  
Derivatives Of

scholarly journals Protein-ligand interactions of CYP51 Candida glabrata and human CYP11В1 with 7-substituted 19-nortestosterones

2019 ◽  
Vol 54 (4) ◽  
pp. 450-454
Author(s):  
T. V. Shkel ◽  
I. P. Grabovec ◽  
A. A. Gilep ◽  
T. S. Varaksa ◽  
N. V. Strushkevich ◽  
...  
Keyword(s):  
Active Center ◽  
Candida Glabrata ◽  
Pathogenic Fungi ◽  
Methyl Group ◽  
Protein Ligand Interactions ◽  
Androstane Series ◽  
Ligand Interactions ◽  
Derivatives Of ◽  
Heteroaromatic Acids

The interaction of human monooxygenases and pathogenic fungi with previously obtained esters of isomeric 7-methyl-19-nor-testosterones and a number of heteroaromatic acids – derivatives of pyridine and pyrazine, was studied. Interaction with the active center of CYP11B1 derivatives of steroids of the androstane series containing methyl group at C7 and residues of heteroaromatic acids at C17β is shown.

Synthesis of derivatives of the androstane series

1966 ◽  
Vol 2 (5) ◽  
pp. 290-294 ◽  
Author(s):  
L. N. Volovel'skii
Keyword(s):  
Androstane Series ◽  
Derivatives Of

RELATIVE EFFECTIVENESS OF VARIOUS STEROIDS IN AN ANDROGEN ASSAY USING THE EXORBITAL LACRIMAL GLAND OF THE CASTRATED RAT.

1967 ◽  
Vol 55 (1) ◽  
pp. 131-135 ◽  
Author(s):  
Cesare Cavallero ◽  
Peter Ofner
Keyword(s):  
Lacrimal Gland ◽  
Relative Effectiveness ◽  
Preceding Paper ◽  
Fold Increase ◽  
Morphological Transformation ◽  
Methyl Substitution ◽  
Androgenic Activity ◽  
Androstane Series ◽  
Derivatives Of ◽  
Androstane Derivatives

ABSTRACT The morphological transformation of the exorbital lacrimal gland of the castrated rat following subcutaneous injection of steroids, described in detail in the preceding paper, was employed as the end-point of androgenic activity. The relative effectiveness of androsterone and of thirteen derivatives of the 5α-androstane series was then determined using testosterone as reference standard. Androsterone proved one-half as active as the standard; 5α-androstan-17β-ol, 5α-androstane-3β,17β-diol and 5α-androst-1-ene-3,17-dione were much less active, whereas 5α-androstane-3α,17β-diol was 3 times as potent as testosterone. Introduction of a conjugated double bond at C 1,2 of 17β-hydroxy-5α-androstan-3-one produced a four-fold increase of activity from a level a little lower than that of testosterone; a further increase in androgenicity was obtained on methyl substitution at C 1 of the Δ1-5α-isomer of testosterone. Esterification consistently increased the activities of the 5α-androstane derivatives tested.

ChemInform Abstract: Synthesis of Pyrazoline and Isoxazoline Derivatives of the Androstane Series.

ChemInform ◽  
2010 ◽  
Vol 24 (41) ◽  
pp. no-no
Author(s):  
A. U. SIDDIQUI ◽  
D. RAMESH ◽  
Y. SATYANARAYANA ◽  
M. SRINIVAS ◽  
A. H. SIDDIQUI
Keyword(s):  
Androstane Series ◽  
Derivatives Of

Physical Properties of TCNQ Salts with N-Methyl Derivatives of Pyridine

1982 ◽  
Vol 85 (1) ◽  
pp. 257-263 ◽  
Author(s):  
A. Graja ◽  
M. Przybylski ◽  
B. Butka ◽  
R. Swietlik
Keyword(s):  
Physical Properties ◽  
Methyl Derivatives ◽  
Derivatives Of
Sign in / Sign up

Export Citation Format

Share Document