Plasma theophylline level and effect on lung function after oral and rectal administration of aminophylline

1979 ◽  
Vol 15 (6) ◽  
pp. 401-406 ◽  
Author(s):  
H. Lamont ◽  
E. Moerman ◽  
M. Bogaert ◽  
M. Van Der Straeten ◽  
R. Pauwels
Keyword(s):  
Lung Function ◽  
Rectal Administration ◽  
Theophylline Level ◽  
Plasma Theophylline

scholarly journals Salivary and Urine Theophylline Levels in Management of Childhood Asthma

1981 ◽  
Vol 74 (6) ◽  
pp. 415-418 ◽  
Author(s):  
S J Goldsworthy ◽  
M Kemp ◽  
J O Warner
Keyword(s):  
Body Weight ◽  
Surface Area ◽  
Childhood Asthma ◽  
Slow Release ◽  
Simple Method ◽  
Serum Theophylline ◽  
Theophylline Level ◽  
Serum Theophylline Level ◽  
Plasma Theophylline ◽  
Urine Levels

It is not possible to predict the plasma theophylline levels that can be achieved using slow-release aminophylline based on body weight or surface area. Improvement in FEV1 is directly related to increasing serum theophylline level, justifying the need for measuring levels in order to optimize therapy. As repeated venesection in children is unpleasant we have studied a simple method using saliva. Simultaneous blood and salivary theophylline levels correlated sufficiently well for salivary levels to be used for monitoring purposes. Urine levels did not correlate as well, but could be used for checking compliance.

Plasma theophylline concentration and lung function in ponies with recurrent obstructive lung disease

1990 ◽  
Vol 22 (3) ◽  
pp. 194-197 ◽  
Author(s):  
B. C. McKIERNAN ◽  
G. D. KORITZ ◽  
JACQUELINE S. SCOTT ◽  
CATHY BERNEY ◽  
N. E. ROBINSON
Keyword(s):  
Lung Function ◽  
Lung Disease ◽  
Obstructive Lung Disease ◽  
Theophylline Concentration ◽  
Plasma Theophylline

No effect of artificial gravity on lung function with exercise training during head-down bed rest

2015 ◽  
pp. 1-7
Author(s):  
Longxiang Su ◽  
Yinghua Guo ◽  
Yajuan Wang ◽  
Delong Wang ◽  
Changting Liu
Keyword(s):  
Lung Function ◽  
Pulse Rate ◽  
Vital Capacity ◽  
Pulmonary Ventilation ◽  
Bed Rest ◽  
Forced Expiratory Volume ◽  
Observation Time ◽  
Artificial Gravity ◽  
Postural Changes ◽  
Expiratory Flow

AbstractTo explore the effectiveness of microgravity simulated by head-down bed rest (HDBR) and artificial gravity (AG) with exercise on lung function. Twenty-four volunteers were randomly divided into control and exercise countermeasure (CM) groups for 96 h of 6° HDBR. Comparisons of pulse rate, pulse oxygen saturation (SpO2) and lung function were made between these two groups at 0, 24, 48, 72, 96 h. Compared with the sitting position, inspiratory capacity and respiratory reserve volume were significantly higher than before HDBR (0° position) (P< 0.05). Vital capacity, expiratory reserve volume, forced vital capacity, forced expiratory volume in 1 s, forced inspiratory vital capacity, forced inspiratory volume in 1 s, forced expiratory flow at 25, 50 and 75%, maximal mid-expiratory flow and peak expiratory flow were all significantly lower than those before HDBR (P< 0.05). Neither control nor CM groups showed significant differences in the pulse rate, SpO2, pulmonary volume and pulmonary ventilation function over the HDBR observation time. Postural changes can lead to variation in lung volume and ventilation function, but a HDBR model induced no changes in pulmonary function and therefore should not be used to study AG CMs.

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