Interaction of desipramine and amitriptyline with adrenergic mechanisms in the human iris in vivo

1981 ◽  
Vol 19 (6) ◽  
pp. 403-408 ◽  
Author(s):  
E. Szabadi ◽  
P. Gaszner ◽  
C. M. Bradshaw
Keyword(s):  
Adrenergic Mechanisms ◽  
Human Iris

Differential interactions of phenobarbital and pentobarbital with β-adrenergic mechanisms in vitro and in vivo

1977 ◽  
Vol 54 (3) ◽  
pp. 453-466 ◽  
Author(s):  
H.C. Sabelli ◽  
B.I. Diamond ◽  
J. May ◽  
H.S. Havdala
Keyword(s):  
Adrenergic Mechanisms

scholarly journals Hyperspectral optical imaging of human iris in vivo: characteristics of reflectance spectra

2011 ◽  
Vol 16 (7) ◽  
pp. 076001 ◽  
Author(s):  
José M. Medina ◽  
Luís M. Pereira ◽  
Hélder T. Correia ◽  
Sérgio M. C. Nascimento
Keyword(s):  
Optical Imaging ◽  
Reflectance Spectra ◽  
Human Iris

Imaging and Confocal Systems for in vivo Measurements of Human-Iris Spectral Reflectance

2014 ◽  
Vol 10 (7) ◽  
pp. 595-600
Author(s):  
Yi-Chun Chen ◽  
Chong-Jhih Jiang ◽  
Jian-Siang Huang ◽  
Szu-Yu Chen ◽  
Ching-Cherng Sun
Keyword(s):  
Spectral Reflectance ◽  
In Vivo Measurements ◽  
Human Iris

Relative agonist potency as a means of differentiating α-adrenoceptors and α-adrenergic mechanisms

1985 ◽  
Vol 68 (s10) ◽  
pp. 9s-15s ◽  
Author(s):  
Robert R. Ruffolo
Keyword(s):  
Guinea Pig ◽  
Species Differences ◽  
Dissociation Constants ◽  
Rat Aorta ◽  
Adrenergic Mechanisms ◽  
Qualitative And Quantitative ◽  
Adrenoceptor Agonists ◽  
Relative Potencies

1. Relative potencies (ED50), affinities (assessed as dissociation constants) and efficacies (i.e. ability to activate the receptor) of agonists are useful in subclassifying and differentiating α-adrenoceptors. 2. The postsynaptic α-adrenoceptor of rat aorta is of the α1-subtype, but may differ from the α1-adrenoceptor of rabbit and guinea pig aortae, based on comparison of relative potencies of selected agonists. 3. By evaluating the relative potency of agonists, qualitative and quantitative species differences between α1-adrenoceptors in rat and guinea pig are observed in a variety of test systems in vivo and in vitro. 4. By comparing the relative potencies of aromatic hydroxyl-substituted phenethylamines and imidazolines at α1-adrenoceptors in guinea pig aorta, differences in the ability of these two classes of α-adrenoceptor agonists to bind to, and subsequently activate, α1-adrenoceptors have been observed. 5. Evaluating the relative potencies of agonists, when used in conjunction with other techniques, provides a valuable method for classifying α-adrenoceptors and for studying α-adrenergic mechanisms.

In vivo non‐contact measurement of human iris elasticity by optical coherence elastography

2021 ◽  
Author(s):  
Shuling Ye ◽  
Yuheng Zhou ◽  
Chenhong Bao ◽  
Yulei Chen ◽  
Fan Lu ◽  
...  
Keyword(s):  
Optical Coherence ◽  
Contact Measurement ◽  
Human Iris

Fine Structural Changes in the Microvasculature of the Mouse Pinna: Aging and Radiation Injury

1974 ◽  
Vol 32 ◽  
pp. 54-55
Author(s):  
S. Phyllis Steamer ◽  
Rosemarie L. Devine
Keyword(s):  
Structural Changes ◽  
Radiation Treatment ◽  
Arterial Stenosis ◽  
Ultrastructural Changes ◽  
Vascular Effects ◽  
Microvascular Changes ◽  
Surrounding Connective Tissue ◽  
Fission Neutrons ◽  
Total Body

The importance of radiation damage to the skin and its vasculature was recognized by the early radiologists. In more recent studies, vascular effects were shown to involve the endothelium as well as the surrounding connective tissue. Microvascular changes in the mouse pinna were studied in vivo and recorded photographically over a period of 12-18 months. Radiation treatment at 110 days of age was total body exposure to either 240 rad fission neutrons or 855 rad 60Co gamma rays. After in vivo observations in control and irradiated mice, animals were sacrificed for examination of changes in vascular fine structure. Vessels were selected from regions of specific interest that had been identified on photomicrographs. Prominent ultrastructural changes can be attributed to aging as well as to radiation treatment. Of principal concern were determinations of ultrastructural changes associated with venous dilatations, segmental arterial stenosis and tortuosities of both veins and arteries, effects that had been identified on the basis of light microscopic observations. Tortuosities and irregularly dilated vein segments were related to both aging and radiation changes but arterial stenosis was observed only in irradiated animals.

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