Blood pressure response to enalaprilic acid in essential hypertension: Dose-response and effect of pre-treatment with furosemide

1985 ◽  
Vol 29 (1) ◽  
pp. 9-15 ◽  
Author(s):  
G. J. Navis ◽  
P. E. de Jong ◽  
A. J. M. Donker ◽  
G. K. van der Hem ◽  
D. de Zeeuw
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Dose Response ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Pre Treatment ◽  
Enalaprilic Acid

scholarly journals Prolonged duration of blood pressure response to enalkiren, the novel dipeptide renin inhibitor, in essential hypertension.

Hypertension ◽  
1990 ◽  
Vol 15 (6_pt_2) ◽  
pp. 835-840 ◽  
Author(s):  
R S Boger ◽  
H N Glassman ◽  
J H Cavanaugh ◽  
P J Schmitz ◽  
J Lamm ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Renin Inhibitor ◽  
The Novel ◽  
Prolonged Duration

Objective Measurement of Performance during Acute Stress in Patients with Essential Hypertension: Assessment of the Effects of Propranolol and Metoprolol

1979 ◽  
Vol 57 (s5) ◽  
pp. 413s-415s ◽  
Author(s):  
F. G. Dunn ◽  
A. R. Lorimer ◽  
T. D. V. Lawrie
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Single Dose ◽  
Acute Stress ◽  
Blood Pressure Response ◽  
Objective Measurement ◽  
Pressure Response ◽  
Blocking Agents ◽  
Response To Stress ◽  
Car Driving

1. A standardized method of objectively measuring performance during simulated car driving is described. 2. The effect of a single dose of propranolol and metoprolol were compared with placebo in two groups of patients with untreated essential hypertension. 3. Performance was similar after β-adrenoreceptor-blocking agents or placebo. 4. Blood pressure response to stress persisted after administration of the blocking agents.

scholarly journals Blood Pressure Control and Exaggerated Blood Pressure Response in Nigerians with Essential Hypertension

2014 ◽  
Vol 8 ◽  
pp. CMC.S15961
Author(s):  
Olugbenga O. Abiodun ◽  
Michael O. Balogun ◽  
Rasaaq A. Adebayo ◽  
Anthony O. Akintomide
Keyword(s):  
Blood Pressure ◽  
Logistic Regression ◽  
Essential Hypertension ◽  
Exercise Testing ◽  
Blood Pressure Response ◽  
Pressure Control ◽  
General Linear Model ◽  
Pressure Response ◽  
Chi Square ◽  
Key Factor

Background Blood pressure (BP) control in hypertensives is important in preventing cardiovascular (CV) morbidity and mortality. This work was done to assess control of BP among Nigerian hypertensives at rest and during exercise. Materials and Methods A total of 85 male hypertensives were recruited consecutively and had clinical evaluation and treadmill (TM) exercise testing using the Bruce protocol. Independent t-test, chi-square, and Fisher's exact tests were used to compare patients with controlled and uncontrolled BP using SPSS version 16 software. Adjustment for confounders was by logistic regression and general linear model. Results Resting systolic BP (rSBP) (mmHg) and resting diastolic BP (rDBP) (mmHg) were significantly lower in the controlled group (115.0 ± 12.29, 133.1 ± 12.27, P = < 0.001 and 76.00 ± 6.55, 91.4 ± 8.00, P = < 0.001). The proportion of subjects with controlled BP was 37.7%. Adjusted peak SBP (PSBP) during exercise (mmHg) was significantly higher in the uncontrolled than in the controlled group (210.5 ± 27.31, 191.8 ± 20.77, P = 0.001). Adjusted exaggerated blood pressure response (EBPR) was found in 37 subjects (44%) in the uncontrolled group while seven subjects (0.1%) had EBPR in the controlled group ( P = 0.003). Conclusion This study shows that EBPR is significantly higher in subjects with uncontrolled BP compared with those with controlled BP. Therefore, good BP control may be the key factor in preventing EBPR in hypertensives.

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