Alteration of Fc-receptor phenotype and proliferative capacity of Fc-IgG-receptor positive lymphocytes through interaction with soluble immune complexes of patients with SLE or RA

1985 ◽  
Vol 5 (3) ◽  
pp. 127-132 ◽  
Author(s):  
M. Thien ◽  
D. Renger ◽  
H. Deicher ◽  
W. J. Pichler
Keyword(s):  
Immune Complexes ◽  
Fc Receptor ◽  
Proliferative Capacity ◽  
Soluble Immune Complexes ◽  
Receptor Phenotype

scholarly journals Immunohistochemical detection of Fc receptor. I. Light microscopic demonstration of Fc receptor by using soluble immune complexes of peroxidase-antiperoxidase immunoglobulin G.

1977 ◽  
Vol 25 (4) ◽  
pp. 252-258 ◽  
Author(s):  
G Itoh ◽  
S Miura ◽  
I Suzuki
Keyword(s):  
Cell Surface ◽  
Immunoglobulin G ◽  
Immune Complexes ◽  
Surface Characterization ◽  
Fc Receptor ◽  
Frozen Sections ◽  
Microscopic Demonstration ◽  
Lymph Node Cells ◽  
Soluble Immune Complexes ◽  
And Control

The mouse mesenteric lymph node cells (in the cell suspension and frozen sections) were incubated in the soluble immune complexes of peroxidase-antiperoxidase immunoglobulin G. After being washed, they were reacted with diaminobenzidine tetrahydrochloride. Light microscopically brown-colored granules were observed on the cell surface of a proportion of small lymphocytes. In frozen sections, a proportion of small lymphocytes were stained dark brown on the cell surface. Characterization and control experiments suggest that the binding of peroxidase-antiperoxidase immunoglobulin G to the cell surface is mediated by Fc receptor. Peroxidase-antiperoxidase immunoglobulin G, therefore, can be used as in indicator of Fc receptor.

scholarly journals Effects of soluble immune complexes on Fc receptor- and C3b receptor-mediated phagocytosis by macrophages.

1980 ◽  
Vol 152 (4) ◽  
pp. 905-919 ◽  
Author(s):  
F M Griffin
Keyword(s):  
Immune Complexes ◽  
Fc Receptors ◽  
Fc Receptor ◽  
Complement Receptor ◽  
Complement Receptors ◽  
Phagocytic Function ◽  
Receptor Function ◽  
Coated Particles ◽  
C3b Receptor ◽  
Soluble Immune Complexes

The effects of ingestion of soluble immune complexes upon macrophage phagocytic function was studied. Ingestion of immune complexes severely impaired the macrophage's ability to ingest IgG-coated particles but did not alter its ability to interact with particles by means other than its Fc receptors. Treatment of macrophages that had ingested immune complexes with supernates containing the previously described lymphokine that augments macrophage complement receptor function failed to enhance the cells' interaction with either IgG-coated erythrocytes or zymosan particles but markedly enhanced their ability to phagocytize via their complement receptors. The possible significance of these findings in immunologically mediated inflammation is discussed.

scholarly journals Immunohistochemical detection of Fc receptor. II. Electron microscopic demonstration of Fc receptor by using soluble immune complexes of ferritin-antiferritin immunoglobulin G.

1977 ◽  
Vol 25 (4) ◽  
pp. 259-265 ◽  
Author(s):  
G Itoh ◽  
I Suzuki
Keyword(s):  
Lymph Node ◽  
Cell Surface ◽  
Immunoglobulin G ◽  
Immune Complexes ◽  
Fc Receptor ◽  
Electron Microscopic ◽  
Microscopic Features ◽  
Lymph Node Cells ◽  
Soluble Immune Complexes ◽  
Ethanol Series

The mouse mesenteric lymph node cells were incubated in the soluble immune complexes of ferritin-antiferritin immunoglobulin G at 37 degrees C for 20 min. After being washed, postfixed with OsO4 and dehydrated by degraded ethanol series, the lymph node cells were observed by electron microscope. Apprroximately 15% of the cells (mainly composed of small lymphocytes) bound ferritin particles to the cell surface. The distribution pattern of the binding of ferritin particles (ferritin-antiferritin immunoglobulin G) took the form of discrete patches of irregular distribution interspaced with unlabeled portions. The electron microscopic features of ferritin particles (ferritin-antiferritin immunoglobulin G) attached to the cell surface suggest that a structure of constant conformation (Fc receptor) situated in the cell membrane takes part in the binding of ferritin-antiferritin immunoglobulin G.

Isoelectric focusing analysis of soluble immune complexes bound to Protein A-sepharose

1981 ◽  
Vol 111 (2) ◽  
pp. 336-342 ◽  
Author(s):  
Bert W. Maidment ◽  
Lawrence D. Papsidero ◽  
Marie Gamarra ◽  
Takuma Nemoto ◽  
T.Ming Chu
Keyword(s):  
Isoelectric Focusing ◽  
Immune Complexes ◽  
Protein A ◽  
Soluble Immune Complexes

Uptake of Intravenously Administered Soluble Immune Complexes by Type I Alveolar Cells and Macrophages in Mice

1985 ◽  
Vol 78 (1) ◽  
pp. 108-111
Author(s):  
Y. Kanayama ◽  
K. Amatsu ◽  
N. Negoro ◽  
T. Takeda ◽  
T. Inoue
Keyword(s):  
Immune Complexes ◽  
Type I ◽  
Alveolar Cells ◽  
Soluble Immune Complexes
Sign in / Sign up

Export Citation Format

Share Document