Concanavalin A-induced suppressor cell activity and in vitro immunoglobulin secretion in rheumatoid arthritis: Correlation with clinical and immunological parameters

1981 ◽  
Vol 1 (3) ◽  
pp. 115-120 ◽  
Author(s):  
J. S. Smolen ◽  
G. Lanzer ◽  
O. Scherak ◽  
E. J. Menzel ◽  
W. R. Mayr ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Concanavalin A ◽  
Cell Activity ◽  
Suppressor Cell ◽  
Immunological Parameters ◽  
Immunoglobulin Secretion

Concanavalin A-induced suppressor cell activity for T-cell proliferative responses: Autologous and allogeneic suppression in aging humans

1980 ◽  
Vol 56 (1) ◽  
pp. 80-88 ◽  
Author(s):  
Richard S. Schulof ◽  
John A. Garofalo ◽  
Robert A. Good ◽  
Sudhir Gupta
Keyword(s):  
T Cell ◽  
Concanavalin A ◽  
Cell Activity ◽  
Suppressor Cell

Prednisolone inhibits LPS-induced bone marrow suppressor cell activity in vitro but not in vivo

2003 ◽  
Vol 3 (2) ◽  
pp. 169-178 ◽  
Author(s):  
Kristi A Haskins ◽  
Scott M Schlauder ◽  
James H Holda
Keyword(s):  
Bone Marrow ◽  
Cell Activity ◽  
Suppressor Cell

Induction of suppressor cell activity in vivo and suppression of lymphoproliferative responses in vitro by SK&F 105685 in the dog

1992 ◽  
Vol 23 (2) ◽  
pp. 67-74 ◽  
Author(s):  
Patricia A. Thiem ◽  
Johanne M. Kaplan ◽  
Peter J. Bugelski ◽  
Elizabeth V. Ruggieri ◽  
Alison M. Badger
Keyword(s):  
Cell Activity ◽  
Suppressor Cell

Concanavalin A-Induced Suppressor Cell Activity in Focal Glomerular Sclerosis

Nephron ◽  
1982 ◽  
Vol 31 (1) ◽  
pp. 27-30 ◽  
Author(s):  
Koichi Matsumoto ◽  
Kotaro Osakabe ◽  
Hisashi Katayama ◽  
Michinobu Hatano
Keyword(s):  
Concanavalin A ◽  
Cell Activity ◽  
Suppressor Cell ◽  
Glomerular Sclerosis ◽  
Focal Glomerular Sclerosis

scholarly journals A morphologic and immunologic study of the large granular lymphocyte in neutropenia with T lymphocytosis

Blood ◽  
1984 ◽  
Vol 63 (5) ◽  
pp. 1133-1140 ◽  
Author(s):  
WC Chan ◽  
I Check ◽  
C Schick ◽  
RK Brynes ◽  
J Kateley ◽  
...  
Keyword(s):  
Cell Activity ◽  
Suppressor Cell ◽  
Strong Acid ◽  
Pokeweed Mitogen ◽  
Cell Phenotype ◽  
Mixed Lymphocyte Cultures ◽  
Dependent Cell ◽  
Granular Lymphocytes

Abstract We report four patients with expansion of a unique population of lymphocytes that is consistently associated with neutropenia. Two patients also had rheumatoid arthritis and autoantibodies. The lymphocytes contained many cytoplasmic azurophilic granules, which possessed strong acid phosphatase activity. Multiple cytoplasmic parallel tubular arrays were observed ultrastructurally. These granular lymphocytes showed the T suppressor/cytotoxic cell phenotype (E+, OKT3+, OKT8+, OKT4-, OKM1-, OKI1-) and exhibited antibody-dependent cell-mediated cytotoxic activity but little or no natural killer cytotoxicity. They did not respond to recall antigens, concanavalin A, or pokeweed mitogen, but the cells from one patient did respond to phytohemagglutinin. No in vitro suppressor cell activity on mitogenic responses of allogeneic cells and on mixed lymphocyte cultures could be demonstrated. There was no evidence of suppression of immunoglobulin synthesis in vivo. It is uncertain that the expansion of this subset of lymphocytes represents a leukemic process. Their constant association with neutropenia, however, raises the possibility that the increase in large granular lymphocytes and neutropenia might be pathogenetically related.

Concanavalin A-induced suppressor cell activity in Hodgkin's disease

1980 ◽  
Vol 16 (4) ◽  
pp. 454-462 ◽  
Author(s):  
Richard S. Schulof ◽  
Burton J. Lee ◽  
Mortimer J. Lacher ◽  
David J. Straus ◽  
Bayard D. Clarkson ◽  
...  
Keyword(s):  
Concanavalin A ◽  
Hodgkin's Disease ◽  
Hodgkin’S Disease ◽  
Cell Activity ◽  
Suppressor Cell
Sign in / Sign up

Export Citation Format

Share Document