Quantitative estimates for isotopic dilution analysis in mass spectrometry

1979 ◽  
Vol 294 (2-3) ◽  
pp. 107-111 ◽  
Author(s):  
W. Schramm ◽  
Tom Louton ◽  
W. Schill
Keyword(s):  
Mass Spectrometry ◽  
Isotopic Dilution ◽  
Quantitative Estimates ◽  
Isotopic Dilution Analysis

Isotopic dilution analysis by solvent extraction—V☆Determination of traces of iron

Talanta ◽  
1963 ◽  
Vol 10 (4) ◽  
pp. 375-381 ◽  
Author(s):  
Jiří Starý ◽  
Jaromír Ru̇žička ◽  
Milan Salamon
Keyword(s):  
Solvent Extraction ◽  
Isotopic Dilution ◽  
Isotopic Dilution Analysis

Isotopic exchanges in the treatment of cyclobutane with tritiated or deuterated trifluoromethanesulfonic acid or with tritiated sulfuric acid

1980 ◽  
Vol 58 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Choi Chuck Lee ◽  
Eric C. F. Ko
Keyword(s):  
Mass Spectrometry ◽  
Sulfuric Acid ◽  
Trifluoromethanesulfonic Acid ◽  
Isotopic Dilution ◽  
Chain Mechanism

When cyclobutane (1) is shaken at 0 °C with [3H]CF3SO3H (2-t) or with (2H)CF3SO3H (2-d), incorporation of T or D into the hydrocarbon layer readily occurred. All eight H atoms of 1 can be involved in the exchange since polydeuterated species including octadeuterated hydrocarbons were observed by mass spectrometry. In an experiment with 1 and 2-t, quenching of the acid layer with H2O gave a mixture of cyclobutanol, cyclopropylcarbinol, and allylcarbinol in the ratio of 61:37:2, respectively, as estimated by isotopic dilution, while vpc analysis of the hydrocarbon layer showed the presence of 1, methylcyclopropane, and 1-butene in the ratio of 66:30:4. The results are explained by a carbocationic chain mechanism, involving the formation of equilibrating bicyclobutonium ions. Similar but slower incorporation of T into the hydrocarbon layer was observed when 1 was treated with [3H]H2SO4.

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