Plasma and suction blister fluid levels of etretinate and its main metabolite during treatment of psoriasis

1981 ◽  
Vol 272 (1-2) ◽  
pp. 147-149 ◽  
Author(s):  
J. Lauharanta ◽  
U. Paravicini
Keyword(s):  
Blister Fluid ◽  
Main Metabolite ◽  
Suction Blister ◽  
Suction Blister Fluid ◽  
Fluid Levels

Blood and Tissue Fluid Levels of a New Non-Steroidal Anti-Inflammatory Preparation of Nabumetone

1987 ◽  
Vol 15 (6) ◽  
pp. 368-373 ◽  
Author(s):  
D. Torre ◽  
C. Sampietro ◽  
F. Maggiolo
Keyword(s):  
Oral Dose ◽  
The Body ◽  
Concentration Curve ◽  
Tissue Fluid ◽  
Blister Fluid ◽  
Suction Blister ◽  
Suction Blister Fluid ◽  
Pharmacokinetic Properties ◽  
Anti Inflammatory ◽  
Fluid Levels

The pharmacokinetic properties of a new non-steroidal anti-inflammatory preparation of nabumetone have been studied in both plasma and extravascular fluids. The skin suction blister technique was used on six healthy volunteers on two separate occasions and gave good, reproducible results. A single oral dose of 1 g nabumetone achieved significant blood and skin suction blister fluid concentrations. The partition index (area under the concentration curve for the skin suction blister/area under the concentration curve for blood) showed that the orally administered drug was well diffused within the body.

Interferon in suction blister fluid from psoriatic lesions

1983 ◽  
Vol 108 (3) ◽  
pp. 295-299 ◽  
Author(s):  
J.R. BJERKE ◽  
J.K. LIVDEN ◽  
M. DEGRE ◽  
R. MATRE
Keyword(s):  
Blister Fluid ◽  
Suction Blister ◽  
Suction Blister Fluid ◽  
Psoriatic Lesions

Soluble CD14 Monocyte Antigen in Suction Blister Fluid and Serum of Patients with Psoriasis

Dermatology ◽  
1993 ◽  
Vol 186 (1) ◽  
pp. 45-49 ◽  
Author(s):  
R.E. Schopf ◽  
J. Dobmeyer ◽  
T. Dobmeyer ◽  
B. Morsches
Keyword(s):  
Blister Fluid ◽  
Soluble Cd14 ◽  
Suction Blister ◽  
Suction Blister Fluid

Prostacyclin, thromboxane and prostaglandin F2αin suction blister fluid of human skin: Effect of systemic aspirin and local glucocorticosteroid treatment

Life Sciences ◽  
1981 ◽  
Vol 29 (4) ◽  
pp. 391-396 ◽  
Author(s):  
Aarne Oikarinen ◽  
Lasse Viinikka ◽  
Heikki Rytsälä ◽  
Urpo Kiistala ◽  
Olavi Ylikorkala
Keyword(s):  
Human Skin ◽  
Skin Effect ◽  
Blister Fluid ◽  
Suction Blister ◽  
Suction Blister Fluid

Determination of 8-methoxypsoralen in suction-blister fluid and serum by liquid chromatography.

1980 ◽  
Vol 26 (13) ◽  
pp. 1825-1828 ◽  
Author(s):  
M J Herfst ◽  
P M Edelbroek ◽  
F A de Wolff
Keyword(s):  
High Performance ◽  
Internal Standard ◽  
Reversed Phase ◽  
Pharmacokinetic Studies ◽  
Blister Fluid ◽  
Liquid Chromatograph ◽  
Suction Blister ◽  
Drug Concentrations ◽  
Suction Blister Fluid

Abstract A method is described for determination of 8-methoxypsoralen to 0.2 mL of suction-blister fluid or 1 mL of serum from psoriatic patients being treated with this drug. The drug is extracted from the biological matrix at pH 9.0 with a mixture of dichloromethane and light petroleum ether. 5-Methoxypsoralen is used as internal standard. Separation and quantitation are performed on a “high-performance” liquid chromatograph with use of an RP 18 reversed-phase column and detection at 245 nm. Accuracy and precision are good. Some benzodiazepines and their metabolites interfere. The lowest detectable concentration is 10 microgram/L, which means that the method is sufficiently sensitive to measure the drug concentrations in serum and suction-blister fluid for pharmacokinetic studies in patients being treated with a therapeutic dosage.

Comparison of the Concentrations of 8-MOP in both Plasma and Suction Blister Fluid after Oral Ingestion

1999 ◽  
Vol 11 (4) ◽  
pp. 218
Author(s):  
Un Cheol Yeo ◽  
Sung Hwan Kim ◽  
Myoung Min Kim ◽  
Won Hee Jung ◽  
Kyung Eob Choi ◽  
...  
Keyword(s):  
Blister Fluid ◽  
Oral Ingestion ◽  
Suction Blister ◽  
Suction Blister Fluid

Pharmacokinetics of Lymecycline and Doxycycline in Serum and Suction Blister Fluid

Chemotherapy ◽  
1985 ◽  
Vol 31 (4) ◽  
pp. 261-265 ◽  
Author(s):  
Aksel Schreiner ◽  
Asbjorn Digrams
Keyword(s):  
Blister Fluid ◽  
Suction Blister ◽  
Suction Blister Fluid
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