Impaired histamine metabolism in the arthus reaction induced in guinea-pig skin

1985 ◽  
Vol 277 (4) ◽  
pp. 313-317 ◽  
Author(s):  
S. Imamura ◽  
T. Tachibana ◽  
S. Taniguchi
Keyword(s):  
Guinea Pig ◽  
Arthus Reaction ◽  
Histamine Metabolism ◽  
Pig Skin

scholarly journals Time dependent changes of histamine metabolism and infiltrating cell populations in the Arthus reaction sites prepared in guinea pig skin.

Ensho ◽  
1987 ◽  
Vol 7 (1) ◽  
pp. 47-51
Author(s):  
Takao Tachibana ◽  
Ken-ichi Toda ◽  
Fukumi Furukawa ◽  
Shinkichi Taniguchi ◽  
Sadao Imamura
Keyword(s):  
Guinea Pig ◽  
Time Dependent ◽  
Cell Populations ◽  
Arthus Reaction ◽  
Histamine Metabolism ◽  
Pig Skin

Phospholipids (PL) in the Arthus reaction sites induced in guinea-pig skin

1994 ◽  
Vol 8 (1) ◽  
pp. 84
Author(s):  
T. Tachibana ◽  
S. Taniguchi ◽  
S. Imamura
Keyword(s):  
Guinea Pig ◽  
Arthus Reaction ◽  
Pig Skin

scholarly journals Possible Interaction of Histamine and Serotonin in the Arthus Reaction Induced in Guinea Pig Skin

Dermatology ◽  
1989 ◽  
Vol 179 (1) ◽  
pp. 127-127
Author(s):  
T. Tachibana ◽  
S. Taniguchi ◽  
F. Furukawa ◽  
S. Imamura
Keyword(s):  
Guinea Pig ◽  
Arthus Reaction ◽  
Pig Skin

scholarly journals Cutaneous lipogenesis: precursors utilized by guinea pig skin for lipid synthesis

1971 ◽  
Vol 12 (3) ◽  
pp. 347-360
Author(s):  
VICTOR R. WHEATLEY ◽  
LEONARD T. HODGINS ◽  
WILLIAM M. COON ◽  
MUTUKUMARA KUMARASIRI ◽  
HAROLD BERENZWEIG ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Lipid Synthesis ◽  
Pig Skin

Final Report of the Safety Assessment of Kojic Acid as Used in Cosmetics

2010 ◽  
Vol 29 (6_suppl) ◽  
pp. 244S-273S ◽  
Author(s):  
Christina L. Burnett ◽  
Wilma F. Bergfeld ◽  
Donald V. Belsito ◽  
Ronald A. Hill ◽  
Curtis D. Klaassen ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Safety Assessment ◽  
Expert Panel ◽  
Kojic Acid ◽  
Tumor Promotion ◽  
Final Report ◽  
Cosmetic Products ◽  
Pig Skin ◽  
Animal Data ◽  
Skin Lightening

Kojic acid functions as an antioxidant in cosmetic products. Kojic acid was not a toxicant in acute, chronic, reproductive, and genotoxicity studies. While some animal data suggested tumor promotion and weak carcinogenicity, kojic acid is slowly absorbed into the circulation from human skin and likely would not reach the threshold at which these effects were seen. The available human sensitization data supported the safety of kojic acid at a use concentration of 2% in leave-on cosmetics. Kojic acid depigmented black guinea pig skin at a concentration of 4%, but this effect was not seen at 1%. The Cosmetic Ingredient Review (CIR) Expert Panel concluded that the 2 end points of concern, dermal sensitization and skin lightening, would not be seen at use concentrations below 1%; therefore, this ingredient is safe for use in cosmetic products up to that level.

scholarly journals Transfer of diclofenac sodium across excised guinea pig skin on high-frequency pulse iontophoresis. I. Equivalent circuit model.

1990 ◽  
Vol 38 (4) ◽  
pp. 1019-1021 ◽  
Author(s):  
Tamotsu KOIZUMI ◽  
Masawa KAKEMI ◽  
Kazunori KATAYAMA ◽  
Hirohiko INADA ◽  
Kazuyoshi SUDEJI ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Equivalent Circuit ◽  
High Frequency ◽  
Diclofenac Sodium ◽  
Equivalent Circuit Model ◽  
Circuit Model ◽  
Pig Skin ◽  
Frequency Pulse
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