Effects of dopaminergic and cholinergic drugs, naloxone and l-prolyl-leucyl-glycinamide on LSD-induced catalepsy

1980 ◽  
Vol 313 (1) ◽  
pp. 45-50 ◽  
Author(s):  
Simon Chiu ◽  
Ram K. Mishra
Keyword(s):  
Cholinergic Drugs ◽  
Prolyl Leucyl Glycinamide

Effect of muscarinic cholinergic drugs on ischemia-induced decreases in glucose uptake and CA1 field potentials in rat hippocampus slices

1992 ◽  
Vol 221 (1) ◽  
pp. 113-119 ◽  
Author(s):  
Shibata Shigenobu ◽  
Kodama Koutaroh ◽  
Tominaga Keiko ◽  
Tanaka Takeshi ◽  
Watanabe Shigenori
Keyword(s):  
Glucose Uptake ◽  
Rat Hippocampus ◽  
Field Potentials ◽  
Cholinergic Drugs ◽  
Muscarinic Cholinergic

scholarly journals Anti-Cholinergic Drugs and Memory

1983 ◽  
Vol 143 (4) ◽  
pp. 422-423 ◽  
Author(s):  
Avraham Calev
Keyword(s):  
Cholinergic Drugs

Effect of Cholinergic Drugs on the Perilymphatic Oxygen Tension

1979 ◽  
Vol 88 (5) ◽  
pp. 626-629
Author(s):  
N. Yagi ◽  
U. Fisch
Keyword(s):  
Oxygen Tension ◽  
Intravenous Injection ◽  
Cholinergic Receptors ◽  
Polarographic Method ◽  
Cholinergic Drugs ◽  
Perilymphatic Space

The effect of the intravenous injection of cholinergic drugs on perilymphatic oxygen tension (Po2) was measured using the polarographic method in 20 cats. Acetylcholine, pilocarpine and neostigmine produced minimal but statistically significant changes in perilymphatic Po2. Atropine and scopolamine did not influence the Po2 of the perilymphatic space. The reported results show that under normal conditions the cholinergic receptors of the vestibular vessels have little effect on the permeability of arterial Po2.

Comparison of amantadine, orphenadrine, and placebo in the control of phenothiazine-induced Parkinsonism

1972 ◽  
Vol 2 (4) ◽  
pp. 406-413 ◽  
Author(s):  
R. H. S. Mindham ◽  
R. Gaind ◽  
B. H. Anstee ◽  
Lorna Rimmer
Keyword(s):  
Nervous System ◽  
Practical Importance ◽  
Clinical Signs ◽  
Drug Induced ◽  
Double Blind ◽  
Fluphenazine Decanoate ◽  
Cholinergic Drugs ◽  
Blind Comparison ◽  
Pharmacologically Active ◽  
Active Substances

SynopsisA double-blind comparison was made of the effects of amantadine hydrochloride, orphenadrine hydrochloride, and placebo in the control of the effects on the extrapyramidal nervous system of fluphenazine decanoate. Patients were assessed with regard to the main symptoms of Parkinsonism, the leading clinical signs, performance in walking, writing and squeezing, changes in mood, and unwanted effects of medication. Neither of the pharmacologically active substances was superior to placebo. Attention is drawn to the paucity of evidence for the effectiveness of anti-cholinergic drugs in both Parkinson's disease and in drug-induced Parkinsonism. The special difficulties in performing trials of substances used in relieving the unwanted effects of other drugs are discussed in relationship to defects in methodology in both this and earlier trials. The findings of the present study are not conclusive but show a clear need for further research in this field. The possible theoretical and practical importance of such research is discussed.

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