Liquid-holding recovery of sister chromatid exchanges in UV-irradiated normal and xeroderma pigmentosum complementation groups A and F fibroblasts

1990 ◽  
Vol 282 (1) ◽  
pp. 68-70 ◽  
Author(s):  
S. Arase ◽  
H. Nakanishi ◽  
S. Kodama ◽  
K. Ishizaki
Genetics ◽  
1975 ◽  
Vol 81 (2) ◽  
pp. 349-355
Author(s):  
Sheldon Wolff ◽  
Judy Bodycote ◽  
G H Thomas ◽  
James E Cleaver

ABSTRACT The formation of sister chromatid exchanges has been postulated to depend upon the action of DNA repair enzymes. Our experiments with various human cell lines show that the yield of sister chromatid exchanges is within normal limits in both excision-repair-defective and post-replication-repair-defective cells from the autosomal recessive disease, xeroderma pigmentosum. These results indicate that hypotheses invoking known DNA repair processes to account for the recombination of sister chromatids are inadequate and that the exact enzymatic processes are as yet unknown.


1989 ◽  
Vol 81 (3) ◽  
Author(s):  
Rosa Aledo ◽  
Georges Renault ◽  
Marguerite Prieur ◽  
MarieFran�oise Avril ◽  
Bertrand Chr�tien ◽  
...  

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