Histamine receptors in the guinea pig ileum

1979 ◽  
Vol 309 (1) ◽  
pp. 65-68 ◽  
Author(s):  
G. Bertaccini ◽  
E. Molina ◽  
L. Zappia ◽  
J. Zseli
Keyword(s):  
Guinea Pig ◽  
Histamine Receptors ◽  
Guinea Pig Ileum

scholarly journals Antihistamine activity of the new peptidepreparation from the cod liver

2012 ◽  
Vol 10 (4) ◽  
pp. 49-53
Author(s):  
Kirill Leonidovich Kryshen ◽  
Dmitriy Valentinovich Demchenko ◽  
Olga Nikolayevna Pozharitskaya ◽  
Marina Nikolayevna Makarova ◽  
Yaroslav Aleksandrovich Gushchin ◽  
...  
Keyword(s):  
Cell Culture ◽  
Animal Models ◽  
Guinea Pig ◽  
Sedative Effect ◽  
Histamine Receptors ◽  
Guinea Pig Ileum ◽  
Antihistamine Activity ◽  
Antihistamine Drug ◽  
Release Study ◽  
Peptide Preparation

The effect of the peptide substance on the induced production of histamine by culture of basophile, interaction of the preparation with the H1-histamine receptors and possible sedative effect on animal models were studied. The introduction of the peptide substance in cell culture of basophile didn’t have a significant effect on the histamine release. Study of the interaction of the polypeptide substance with H1-histamine receptors of guinea pig ileum showed that the preparation inhibits the response of unstriated muscles to histamine. The effect was similar to antihistamine drug - ketotifen. In the models of “open field” and “elevated criss-cross labyrinth” it was found that the peptide preparation hasn’t a sedative effect.

scholarly journals H1-histamine receptors may mediate the contractile response of guinea-pig ileum to ‘histamine-free’ splenic extracts

1983 ◽  
Vol 79 (2) ◽  
pp. 373-378 ◽  
Author(s):  
L.F. Ainz ◽  
E. Casis ◽  
J.M. Gandarias ◽  
C.E. Gil-Rodrigo ◽  
J.J. Goiriena Gandarias
Keyword(s):  
Guinea Pig ◽  
Contractile Response ◽  
Histamine Receptors ◽  
Guinea Pig Ileum

Anti-inflammatory effect of Mitragyna speciosa crude methanol extract on the guinea pig ileum

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
WM Shaik Mossadeq ◽  
K Syamimi ◽  
MP Azyyati ◽  
ZA Zakaria ◽  
AK Arifah ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Methanol Extract ◽  
Guinea Pig Ileum ◽  
Mitragyna Speciosa ◽  
Anti Inflammatory ◽  
Crude Methanol Extract ◽  
Inflammatory Effect

Preparation and properties of three analogues of [5-leucine]enkephalin, substrates for enzyme conversion studies

1985 ◽  
Vol 50 (6) ◽  
pp. 1329-1334
Author(s):  
Jaroslav Vičar ◽  
Linda Servítová ◽  
Martin Flegel ◽  
Karel Hauzer ◽  
Tomislav Barth
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
Guinea Pig ◽  
Ion Exchange Chromatography ◽  
Exchange Chromatography ◽  
Guinea Pig Ileum ◽  
Opioid Activity ◽  
C Terminus ◽  
N Terminus ◽  
Fragment Condensation

Analogues of [5-Leu]enkephalin, prolonged by methionine on the N-terminus or, by lysine or methionine on the C-terminus were prepared by fragment condensation, purified by ion exchange chromatography or high-pressure liquid chromatography. The substances were characterised by their opioid activity in a test on guinea-pig ileum in comparison with the activity of [5-Leu]enkephalin.

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