Extensive labelling of injured insect neurons with seven different heme peptides

1983 ◽  
Vol 79 (1) ◽  
pp. 95-104 ◽  
Author(s):  
D. R. N�ssel
Keyword(s):  
Heme Peptides

scholarly journals Permeability of muscle capillaries to small heme-peptides. Evidence for the existence of patent transendothelial channels.

1975 ◽  
Vol 64 (3) ◽  
pp. 586-607 ◽  
Author(s):  
N Simionescu ◽  
M Siminoescu ◽  
G E Palade
Keyword(s):  
Plasma Proteins ◽  
Intercellular Junctions ◽  
Rat Diaphragm ◽  
Enzymic Hydrolysis ◽  
Graphic Analysis ◽  
Heme Peptides ◽  
Future Work ◽  
Hydrolysis Of ◽  
Muscle Capillaries

Two heme-peptides (HP) of about 20-A diameter (heme-undecapeptide [H11P], mol wt approximately 1900 and heme-octapeptide [H8P], mol wt approximately 1550), obtained by enzymic hydrolysis of cytochrome c, were sued as probe molecules in muscle capillaries (rat diaphragm). They were localized in situ by a perixidase reaction, enhanced by the addition of imidazole to the incubation medium. Chromatography of plasma samples showed that HPs circulate predominantly as monomers for the duration of the experiments and are bound by aldehyde fixatives to plasma proteins to the extent of approximately 50% (H8P) to approximately 95% (H11P). Both tracers cross the endothelium primarily via plasmalemmal vesicles which become progressively labeled (by reaction product) from the blood front to the tissue front of the endothelium, in three successive resolvable phases. By the end of each phase the extent of labeling reaches greater than 90% of the corresponding vesicle population. Labeled vesicles appear as either isolated units or chains which form patent channels across the endothelium. The patency of these channels was checked by specimen tilting and graphic analysis of their images. No evidence was found for early or preferential marking of the intercellular junctions and spaces by reaction product. It is concluded that the channels are the most likely candidate for structural equivalents of the small pores of the capillary wall since they are continuous, water-filled passages, and are provided with one or more strictures of less than 100 A. Their frequency remains to be established by future work.

scholarly journals Catalytic Properties of Cytochrome c Heme Peptides

1969 ◽  
Vol 17 (1) ◽  
pp. 82-88 ◽  
Author(s):  
YOSHIHIKO BABA ◽  
HIROSHI MIZUSHIMA ◽  
HIROSHI WATANABE
Keyword(s):  
Cytochrome C ◽  
Catalytic Properties ◽  
Heme Peptides

Molecular Modeling of Heme Peptides: Molecular Dynamics Simulation of Microperoxidase

1994 ◽  
Vol 34 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Graziella Ranghino ◽  
Giovanni Antonini ◽  
Piercarlo Fantucci
Keyword(s):  
Molecular Dynamics ◽  
Molecular Modeling ◽  
Molecular Dynamics Simulation ◽  
Dynamics Simulation ◽  
Heme Peptides

ChemInform Abstract: NEW METHOD FOR THE PREPARATION OF CYTOCHROME C HEME PEPTIDES

1978 ◽  
Vol 9 (45) ◽  
Author(s):  
G. A. VASIL'EVA ◽  
S. K. VOKOV ◽  
A. F. MIRONOV ◽  
R. P. EVSTIGNEEVA
Keyword(s):  
Cytochrome C ◽  
New Method ◽  
Heme Peptides

Antihypoxic activity of heme-peptides of cytochrome c

1987 ◽  
Vol 103 (6) ◽  
pp. 776-779
Author(s):  
A. S. Losev ◽  
Yu. G. Bobkov ◽  
A. I. Lysko ◽  
A. M. Arutyunyan ◽  
A. F. Mironov ◽  
...  
Keyword(s):  
Cytochrome C ◽  
Antihypoxic Activity ◽  
Heme Peptides

On the preparation and mössbauer properties of some heme peptides of cytochrome c

1983 ◽  
Vol 19 (2) ◽  
pp. 165-178 ◽  
Author(s):  
Jim Peterson ◽  
Mohammed M.M. Saleem ◽  
Jack Silver ◽  
Michael T. Wilson ◽  
Ian E.G. Morrison
Keyword(s):  
Cytochrome C ◽  
Heme Peptides
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