Isozyme variability in species of the genus Drosophila. VI. Frequency-property-environment relationships of allelic alcohol dehydrogenases in D. melanogaster

1973 ◽  
Vol 9 (3) ◽  
pp. 213-227 ◽  
Author(s):  
C. L. Vigue ◽  
F. M. Johnson
1987 ◽  
Vol 262 (8) ◽  
pp. 3754-3761
Author(s):  
A.J. Ganzhorn ◽  
D.W. Green ◽  
A.D. Hershey ◽  
R.M. Gould ◽  
B.V. Plapp

1958 ◽  
Vol 232 (1) ◽  
pp. 453-464 ◽  
Author(s):  
Frederic L. Hoch ◽  
Robert J.P. Williams ◽  
Bert L. Vallee

Author(s):  
Aileen Becker ◽  
Dominique Böttcher ◽  
Werner Katzer ◽  
Karsten Siems ◽  
Lutz Müller-Kuhrt ◽  
...  

Abstract Raspberry ketone is a widely used flavor compound in food and cosmetic industry. Several processes for its biocatalytic production have already been described, but either with the use of genetically modified organisms (GMOs) or incomplete conversion of the variety of precursors that are available in nature. Such natural precursors are rhododendrol glycosides with different proportions of (R)- and (S)-rhododendrol depending on the origin. After hydrolysis of these rhododendrol glycosides, the formed rhododendrol enantiomers have to be oxidized to obtain the final product raspberry ketone. To be able to achieve a high conversion with different starting material, we assembled an alcohol dehydrogenase toolbox that can be accessed depending on the optical purity of the intermediate rhododendrol. This is demonstrated by converting racemic rhododendrol using a combination of (R)- and (S)-selective alcohol dehydrogenases together with a universal cofactor recycling system. Furthermore, we conducted a biocatalytic cascade reaction starting from naturally derived rhododendrol glycosides by the use of a glucosidase and an alcohol dehydrogenase to produce raspberry ketone in high yield. Key points • LB-ADH, LK-ADH and LS-ADH oxidize (R)-rhododendrol • RR-ADH and ADH1E oxidize (S)-rhododendrol • Raspberry ketone production via glucosidase and alcohol dehydrogenases from a toolbox Graphical abstract


Author(s):  
Kang-Jia Wang ◽  
Guo-Dong Wang

This article mainly studies the vibration of the carbon nanotubes embedded in elastic medium. A new novel method called the Hamiltonian-based method is applied to determine the frequency property of the nonlinear vibration. Finally, the effectiveness and reliability of the proposed method is verified through the numerical results. The obtained results in this work are expected to be helpful for the study of the nonlinear vibration.


2015 ◽  
Vol 207 ◽  
pp. 1019-1025 ◽  
Author(s):  
J. Razumiene ◽  
E. Cirbaite ◽  
V. Razumas ◽  
V. Laurinavicius

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