New method for the prediction of antibacterial properties of semisynthetic penicillins. 2. Evaluation of activity levels

1989 ◽  
Vol 25 (5) ◽  
pp. 571-575
Author(s):  
G. A. Veinberg ◽  
A. M. Kats ◽  
L. N. Petrulyanis ◽  
L. I. Kononov ◽  
L. S. Gitlina ◽  
...  
Keyword(s):  
Antibacterial Properties ◽  
New Method ◽  
Activity Levels

New method for predicting the antibacterial properties of semisynthetic penicillins.

1989 ◽  
Vol 25 (3) ◽  
pp. 332-338
Author(s):  
G. A. Veinberg ◽  
A. M. Kats ◽  
L. S. Gitlina ◽  
V. E. Golender ◽  
A. B. Rozenblit ◽  
...  
Keyword(s):  
Antibacterial Properties ◽  
New Method

Nanocomposite coatings based on copper and the products of polyethylene destruction, features of their formation, structure and antibacterial properties

RSC Advances ◽  
2016 ◽  
Vol 6 (35) ◽  
pp. 29220-29228 ◽  
Author(s):  
Jinguo Sun ◽  
A. V. Rogachev ◽  
M. A. Yarmolenko ◽  
A. A. Rogachev ◽  
Xiaohong Jiang ◽  
...  
Keyword(s):  
Copper Nanoparticles ◽  
Thermal Destruction ◽  
Antibacterial Properties ◽  
New Method ◽  
Nanocomposite Coatings

A new method of forming coatings containing copper nanoparticles and the products of polyethylene thermal destruction is suggested.

Evaluation of a New System for the Kinetic Measurement of Serum Glutamic Oxalacetic Transaminase

1969 ◽  
Vol 15 (6) ◽  
pp. 496-504 ◽  
Author(s):  
Seymour Winsten ◽  
J Henry Wilkinson ◽  
Joseph H Boutwell
Keyword(s):  
Spectrophotometric Method ◽  
New Method ◽  
Activity Levels ◽  
Good Reproducibility ◽  
Kinetic Measurement ◽  
Glutamic Oxalacetic Transaminase ◽  
Serum Glutamic Oxalacetic Transaminase ◽  
New System

Abstract A new spectrophotometric method for the determination of serum glutamic oxalacetic transaminase§ (SGOT) is described which uses standardized technics and prepackaged reagents. A study was made of this new method in three laboratories and was compared with the routine methods, using identical serum specimens. The new procedure gave good reproducibility and precision. In all methods studied there was evidence of failure of linearity of response at the two highest activity levels examined.

Antithrombin III Activity Levels In Serum: Results Of A Large Survey Study Using A New Method Of Sample Preparation

1981 ◽  
Author(s):  
A Gray ◽  
K Uhlmeyer ◽  
R LaBonte ◽  
L Bailey
Keyword(s):  
Antithrombin Iii ◽  
Collaborative Study ◽  
New Method ◽  
Medical Laboratory ◽  
Survey Study ◽  
Activity Levels ◽  
Serum Samples ◽  
Major Interest ◽  
At Iii

The determination of Antithrombin III (AT III) levels in serum is of major interest because the serum AT III level will reflect both the level of AT III in the circulation (plasma AT III) and the level of procoagulant factors in the circulation (which consume the AT III during serum formation in vitro). Serum samples are also more readily available for testing in reference laboratories who normally receive very few citrated plasma samples. A collaborative study was performed to test AT III levels on all serum samples sent in to the Bio-Diagnostics Medical Laboratory for chemistry panel testing during a one month period.It has been recognized that the level of prothrombin consumption during serum formation will vary widely depending on the sample handling conditions. Only a small amount of thrombin generation is required for complete defibrination of a blood sample. Some serum samples collected in glass without an anticoagulant still had normal plasma levels of prothrombin and AT III. This may indicate early removal of platelets by centrifugation, low levels of contact factors or rapid anticoagulation kinetics. A new method was devised to standardize the complete activation (and thus AT III consumption) of samples received from approximately 800 offices and clinics collecting and mailing the samples under various conditions. To 100 ul sample serum was added 10 ul of commercial thromboplastin/calcium ion solution to activate the sample extrinsically. After at least five minutes, the samples were assayed for their AT III activity using the Quanticheck AT III assay on an Abbott VP. A total of 5800 samples were assayed with a mean value of 83 ± 1 (2 S.D.). There were 132 samples outside of the normal range of 74 ± 20 % AT III (determined on 99 normal adults).

ChemInform Abstract: New Method for the Prediction of Antibacterial Properties of Semisynthetic Penicillins. Part 2. Estimation of the Activity Level.

ChemInform ◽  
1989 ◽  
Vol 20 (49) ◽  
Author(s):  
G. A. VEINBERG ◽  
A. M. KATS ◽  
L. N. PETRULYANIS ◽  
L. I. KONONOV ◽  
L. S. GITLINA ◽  
...  
Keyword(s):  
Antibacterial Properties ◽  
Activity Level ◽  
New Method

scholarly journals Producing metabolic complexes of probiotic microorganisms with significant antimicrobial properties

2021 ◽  
Vol 23 (1) ◽  
pp. 120-125
Author(s):  
O. Yu. Isaienko ◽  
O. V. Kotsar ◽  
T. M. Ryzhkova ◽  
H. I. Diukareva
Keyword(s):  
Antibacterial Activity ◽  
Antibacterial Properties ◽  
Lactobacillus Rhamnosus ◽  
Antimicrobial Properties ◽  
Saccharomyces Boulardii ◽  
Biologically Active ◽  
New Method ◽  
Metabolic Products ◽  
Mueller Hinton Agar ◽  
Method Of Production

The aim of the work – to produce metabolic complexes with significant antibacterial properties using a new proprietary method and to substantiate the prospects of their use for designing of antimicrobial polyfunctional drugs. Materials and methods. Metabolic complexes of Lactobacillus rhamnosus GG, Lactobacillus plantarum, Saccharomyces boulardii, Enterococcus faecium were obtained by culturing the producers in ultrasonic disintegrates of other probiotic microorganisms. Sensitivity of antibiotic-resistant strains of Escherichia coli PR and Staphylococcus haemolyticus PR was determined by qualitative method. The suspension of test-cultures (optical density of 1.0 units on the McFarland scale) after incubation with metabolites (2, 24 and 48 hours at 37 °C) was inoculated into Mueller–Hinton agar. The absence of growth was indicative of the metabolic complexes antibacterial activity against the microorganism. Results. Cultivation of S. boulardii in the S. boulardii / L. rhamnosus / L. plantarum / E. faecium disintegrates, L. plantarum – in the L. rhamnosus / E. faecium disintegrates and L. rhamnosus – in the L. plantarum disintegrates was accompanied by an increase in the biomass of isolated microorganisms (P ≤ 0.03) and production of metabolites. Along with a similar increase in S. boulardii cells in the S. boulardii / L. rhamnosus / L. plantarum / E. faecium disintegrates, the metabolic products of lactobacterial and enterococcal disintegrates exhibited more active inhibitory effects against E. coli PR and S. haemolyticus PR. The increased antibacterial activity indicates the advantage of the new method. Another improvement is the extended spectrum of metabolic complexes owing to producer cultivation in the other probiotic disintegrates to obtain original biologically active substances with high antibacterial properties against pathogens. Among the strength of the method is that all the stages are unified into a single process avoiding multiphase procedure for the separate preparation of one probiotic microorganism disintegrate and the metabolic products of another. Conclusions. Disintegrates as a nutrient medium can be used not only for their own producers, but also for other strains/species and various probiotic microorganisms (fungi and bacteria). The increase in antibacterial activity of metabolic complexes has been found using the new method of production. The prospects of antimicrobial polyfunctional drugs designing on this basis have been proved.

scholarly journals Survey of cold ionospheric outflows in the magnetotail

2009 ◽  
Vol 27 (8) ◽  
pp. 3185-3201 ◽  
Author(s):  
E. Engwall ◽  
A. I. Eriksson ◽  
C. M. Cully ◽  
M. André ◽  
P. A. Puhl-Quinn ◽  
...  
Keyword(s):  
Statistical Study ◽  
Magnetic Activity ◽  
Low Energy ◽  
New Method ◽  
Activity Levels ◽  
Geomagnetic Tail ◽  
The Earth ◽  
Cold Ions ◽  
Low Energy Ions

Abstract. Low-energy ions escape from the ionosphere and constitute a large part of the magnetospheric content, especially in the geomagnetic tail lobes. However, they are normally invisible to spacecraft measurements, since the potential of a sunlit spacecraft in a tenuous plasma in many cases exceeds the energy-per-charge of the ions, and little is therefore known about their outflow properties far from the Earth. Here we present an extensive statistical study of cold ion outflows (0–60 eV) in the geomagnetic tail at geocentric distances from 5 to 19 RE using the Cluster spacecraft during the period from 2001 to 2005. Our results were obtained by a new method, relying on the detection of a wake behind the spacecraft. We show that the cold ions dominate in both flux and density in large regions of the magnetosphere. Most of the cold ions are found to escape from the Earth, which improves previous estimates of the global outflow. The local outflow in the magnetotail corresponds to a global outflow of the order of 1026 ions s−1. The size of the outflow depends on different solar and magnetic activity levels.

Selective Sampling and Orientation of Non-Homogeneous Tissues

1968 ◽  
Vol 26 ◽  
pp. 98-99
Author(s):  
C. C. Clawson ◽  
L. W. Anderson ◽  
R. A. Good
Keyword(s):  
Electron Microscopy ◽  
Electron Microscope ◽  
Light Microscopy ◽  
Random Sampling ◽  
New Method ◽  
Microscope Examination ◽  
Small Areas ◽  
Selective Sampling ◽  
Large Numbers ◽  
Specific Orientation

Investigations which require electron microscope examination of a few specific areas of non-homogeneous tissues make random sampling of small blocks an inefficient and unrewarding procedure. Therefore, several investigators have devised methods which allow obtaining sample blocks for electron microscopy from region of tissue previously identified by light microscopy of present here techniques which make possible: 1) sampling tissue for electron microscopy from selected areas previously identified by light microscopy of relatively large pieces of tissue; 2) dehydration and embedding large numbers of individually identified blocks while keeping each one separate; 3) a new method of maintaining specific orientation of blocks during embedding; 4) special light microscopic staining or fluorescent procedures and electron microscopy on immediately adjacent small areas of tissue.

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