All-union school for instruction in physical methods for the study of heterocyclic compounds

1973 ◽  
Vol 9 (4) ◽  
pp. 535-536
Author(s):  
Ya. Stradyn'
Keyword(s):  
Heterocyclic Compounds ◽  
Physical Methods

THE PYROLYSIS OF OXIMES OF SOME GAMMA CYANO-AND GAMMA NITRO-KETONES

1965 ◽  
Vol 43 (9) ◽  
pp. 2486-2492 ◽  
Author(s):  
C. F. H. Allen
Keyword(s):  
Heterocyclic Compounds ◽  
Beckmann Rearrangement ◽  
Complex Mixtures ◽  
Physical Methods ◽  
New Synthesis ◽  
Independent Synthesis

Oximes of gamma cyano- and gamma nitro-ketones are decomposed by heat as well as by acids. From the very complex mixtures resulting there have been isolated arylated pyrroles, arylated 2-aminopyridines, and the corresponding pyridones, as well as several minor products. This behavior constitutes a new synthesis of these heterocyclic compounds. In a Beckmann rearrangement γ-benzoyl-α,β-diphenylbutyronitrile gave an anilide, the structure of which was confirmed by an independent synthesis. By physical methods both structures of gamma ketonic amides are confirmed.

Probing the Carbon-Nitrogen Bonding in Heterocyclic Compounds with the N K-Shell Excitation Spectroscopy

1997 ◽  
Vol 7 (C2) ◽  
pp. C2-527-C2-528
Author(s):  
St Bender ◽  
R. Franke ◽  
J. Hormes ◽  
A. A. Pavlychev ◽  
N. G. Fominykh ◽  
...  
Keyword(s):  
Heterocyclic Compounds

Antiviral Activity of Fluorinated Heterocyclic Compounds

2016 ◽  
Author(s):  
Liubov Biliavska ◽  
Yulia Pankivska ◽  
Olga Povnitsa ◽  
Svitlana Zagorodnya ◽  
Ganna Gudz ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Heterocyclic Compounds ◽  
Strong Antiviral Activity

SYNTHESIS AND CYTOTOXICITY OF POLYHYDROXYLATED CHOLESTEROL DERIVATIVES

2018 ◽  
Vol 56 (4) ◽  
pp. 467
Author(s):  
Thu Thuy Thi Tran ◽  
Ha Thi Dinh ◽  
Phương Lan Doan ◽  
Long Quoc Pham ◽  
Quang Dai Ngo
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Line ◽  
Cell Lines ◽  
Carcinoma Cell ◽  
Addition Compound ◽  
Hep G2 ◽  
Physical Methods ◽  
Hepatocellular Carcinoma Cell Line ◽  
Human Hepatocellular Carcinoma Cell ◽  
Hepatocellular Carcinoma Cell

Eight polyhydroxylated cholesterol derivatives (1-8) were prepared from cholesterol, using oxidative reagents as SeO2, OsO4/NMO, HCOOH/H2O2 and BH3/ H2O2. Their structures were elucidated by using physical methods including NMR 1D and 2D. These compounds were evaluated against two cancer cell lines (Hep-G2, T98). Compounds 2, 4 and 8 inhibits human hepatocellular carcinoma cell line (Hep-G2) with IC50 4.69, 4.98 and 2.89 µg/mL, respectively. In addition, compound 8 exhibited strong cytotoxicity against T98 cell line (glioblastoma) with IC50 = 2.28 μM.

Synthesis and Characterization of Some New Esters Containing Heterocyclic and Derived From Azo Dyes

2019 ◽  
Vol 9 (02) ◽  
Author(s):  
Zena G. Alrecabi ◽  
Zainab Amer ◽  
Naeemah Al-Lami
Keyword(s):  
Schiff Base ◽  
13C Nmr ◽  
Azo Dyes ◽  
Spectral Methods ◽  
Anthranilic Acid ◽  
Heterocyclic Compounds ◽  
Synthesis And Characterization ◽  
Cooh Group ◽  
Molecular Weights

This study including prepared new colored esters containing heterocyclic with high molecular weights. In the first part of work we synthesized azo dyes [1,2] from the reaction p-toluidine with β-naphthol and o-nitro phenol, thin we synthesized Schiff bases [3,4] by the reaction anthranilic acid with benzaldehyde and dimethyl benzaldehyde. The reaction azo dyes (contain OH group) with Schiff base (contain COOH group) these led to produce the new colored esters [A1-A4]. The second part of work was modification the (C=N-) group in esters to heterocyclic compounds by reacting with phenyl iso cyanide to produce new β-lactam [B1-B4] and with anthranilic acid to get new hydroquinazoline [C1-C4]. All these compounds were characterized by physical properties and spectral methods FTIR, 1H-NMR and 13C-NMR.

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