Rubella vaccination

1988 ◽  
Vol 147 (6) ◽  
pp. 570-573 ◽  
Author(s):  
J. Forster
Keyword(s):  
Rubella Vaccination

scholarly journals Rubella Outbreak in Heballi Agasi Ward, Dharwad District, Karnataka, India, 2014–2015

2020 ◽  
Vol 41 (S1) ◽  
pp. s380-s380
Author(s):  
Sree Kalpana Mohankumar ◽  
Vishweshwarayya Hiremath ◽  
Rajashree Koppad
Keyword(s):  
Attack Rate ◽  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
Routine Immunization ◽  
Serum Samples ◽  
Cross Sectional ◽  
Epidemic Curve ◽  
Surveillance Report ◽  
And Gender ◽  
Rubella Vaccination

Background: Countries that have good rubella surveillance, report ∼10,000–20,000 rubella cases annually. In India, not many cases of rubella are reported. The Hebballi Agasi ward of Dharwad district in Karnataka state, India, reported rubella cases on the last week of January 2015. Objective: We investigated the outbreak by time, place, person, and clinical symptoms. Methods: We performed a cross-sectional study. We defined a case as any resident of Heballi Agasi who had fever and rash, with or without lymphadenopathy, arthralgia, conjunctivitis, coryza, and cough, after December 15, 2014. We collected sociodemographic details and clinical symptoms of patients. We collected 5 serum samples and sent them to the National Measles Laboratory, Bangalore. We tested for measles and rubella antibodies. We drew an epidemic curve and a spot map. We computed mean age of cases, and we calculated attack rates by mean age and gender. We calculated proportions to describe clinical symptoms, and we interviewed stakeholders regarding rubella vaccination. We continued surveillance until March 2015. Results: The population of Heballi Agasi was 1,458. We identified 15 rubella cases (9 girls and 6 boys). The outbreak lasted between December 10, 2014, and February 21, 2015, with a peak on January 16, 2015. The overall attack rate was 1% (15 of 1,458). The mean age of the cases was 6 years (range, 1–23). The attack rate was high (7.7%) among those aged 1–6 years (11 of 143). The attack rate among those aged >6 years was 0.3% (4 of 1,315). In addition to fever and rash, 93% of cases (14 of 15) had coryza, 47% had cough (7 of 15), and 40% had conjunctivitis (6 of 15). Lymphadenopathy was present in only 1 case (1 of 15), and arthralgia was absent among all 15 cases. There was no death among the cases. All 5 sera were positive for rubella and negative for measles. Rubella vaccination was not given for any of the cases because no rubella vaccination is provided in the routine immunization program. Conclusions: There was a rubella outbreak in Heballi Agasi ward. Children aged 1–6 years were most affected. We recommend rubella vaccination in the routine immunization.Funding: NoneDisclosures: None

Rubella vaccination

1993 ◽  
Vol 158 (6) ◽  
pp. 434-434
Author(s):  
Adrian K Thomas
Keyword(s):  
Rubella Vaccination

Evaluation of immunity against rubella in Iranian after mass campaign for measles-rubella vaccination on December 2003

2006 ◽  
Vol 34 (9) ◽  
pp. 588-592 ◽  
Author(s):  
Rasool Hamkar ◽  
Somayeh Jalilvand ◽  
Talat Mokhtari-Azad ◽  
Keramat Nouri Jelyani ◽  
Rakhshandeh Nategh
Keyword(s):  
Mass Campaign ◽  
Rubella Vaccination

Optic Neuritis and Myelitis Following Rubella Vaccination

1982 ◽  
Vol 39 (7) ◽  
pp. 443-444 ◽  
Author(s):  
L. B. Kline ◽  
S. L. Margulies ◽  
S. J. Oh
Keyword(s):  
Optic Neuritis ◽  
Rubella Vaccination

scholarly journals Persistence and Titer Changes of Rubella Virus Antibodies in Primiparous Women Who Had Been Vaccinated with Strain RA 27/3 in Junior High School

2011 ◽  
Vol 19 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Ching-Chiang Lin ◽  
Chun-Yuh Yang ◽  
Yung-Luen Shih ◽  
Yang-Yang Huang ◽  
Tsung-Han Yang ◽  
...  
Keyword(s):  
High School ◽  
Junior High School ◽  
Rubella Virus ◽  
Junior High ◽  
Linear Trend ◽  
Childbearing Age ◽  
Positive Antibody ◽  
Antibody Titers ◽  
Rubella Vaccination ◽  
Primiparous Women

ABSTRACTTaiwan's rubella vaccination program was launched in 1986; each schoolgirl in the third grade of junior high school received one dose of rubella (RA 27/3) vaccine. We reviewed the results of 14,090 prenatal rubella tests for primiparas from three areas of Taiwan during 2002 to 2008 to investigate seronegativity rates and titer changes. In all primiparous women, the average rubella virus seronegativity rate was 6.5% (95% confidence interval [95% CI], 6.1 to 6.9%), and the average rubella virus antibody titer was 65.9 IU/ml (95% CI, 64.7 to 67.1 IU/ml). There were 1,220 women (8.7%) with weakly positive antibody titers (10 to 20 IU/ml). The rubella virus seronegativity rates, which ranged from 5.4 to 9.7%, did not exhibit a linear trend from 9 to 22 years after vaccination (P= 0.201); in contrast, a significant trend appeared in the average rubella virus IgG titer (P= 0.003), dropping from 69.9 IU/ml in the 9th year after vaccination to 54.8 IU/ml in the 22nd year. The mean annual antibody decay rate was −0.77 IU/ml. This study reveals that the level of rubella virus antibodies declined slowly in women of childbearing age who were vaccinated with RA 27/3 at junior high school age. The number of women who were seronegative or had weakly positive antibody titers was still high (15.2%). Therefore, in countries that implement a single-dose regimen in children or teenagers, it should remain an important policy to encourage voluntary immunization in seronegative women and to immunize all postpartum women who are susceptible to rubella virus infection before they leave the hospital.

scholarly journals Associations between race, sex and immune response variations to rubella vaccination in two independent cohorts

Vaccine ◽  
2014 ◽  
Vol 32 (17) ◽  
pp. 1946-1953 ◽  
Author(s):  
Iana H. Haralambieva ◽  
Hannah M. Salk ◽  
Nathaniel D. Lambert ◽  
Inna G. Ovsyannikova ◽  
Richard B. Kennedy ◽  
...  
Keyword(s):  
Immune Response ◽  
Rubella Vaccination

scholarly journals Rubella Antibody Levels in School-Aged Children in Newfoundland: Implications for a Two-Dose Rubella Vaccination Strategy

1997 ◽  
Vol 8 (2) ◽  
pp. 85-88 ◽  
Author(s):  
Samuel Ratnam ◽  
Roy West ◽  
Veeresh Gadag ◽  
Brett Williams ◽  
Elizabeth Oates
Keyword(s):  
Single Dose ◽  
Screening Program ◽  
Serum Antibody ◽  
Vaccination Strategy ◽  
Reproductive Age ◽  
Cluster Sampling ◽  
Age Group ◽  
School Aged Children ◽  
Rubella Vaccination ◽  
The Impact

OBJECTIVE: To determine the prevailing levels of rubella immunity among school-aged children who received a single dose of measles-mumps-rubella (MMR) vaccine at one year of age.DESIGN: Cross-sectional study with a two stage cluster sampling of randomly picked schools across the province of Newfoundland.STUDY POPULATION AND METHODS: A total of 1053, five to 17-year-old children were enrolled; vaccination history was verified through official records; and a sample of blood was taken. Rubella immunity was determined by enzyme immunoassay based on a serum antibody protective cut-off titre of more than 10 IU.RESULTS: A total of 145 (13.8%) were found to be nonimmune. The rate of susceptibility ranged from 3.2% to 25.9% for different age groups. The proportion susceptible was significantly higher at 16.5% in the age group eight to 17 years old versus 3.9% for the age group five to eight years old (χ2=24.08; df=1, P<0.001). There was a significant regression of logarithm titre values on the age of children with an average decline in titre values of 8.1% per annum.CONCLUSIONS: A substantial number of those who were given a single dose of MMR II vaccine may not have protective immunity against rubella as they reach prime reproductive age. There is a definite need to consider a two-dose rubella vaccination strategy in Canada, and these data suggest the second dose given after eight years of age will be most beneficial. In the move towards a routine two-dose measles vaccination strategy in Canada, the MMR II vaccine is being used for the second dose and given either at 18 months of age or at school entry. While this approach will have an overall beneficial effect, the impact of the above timing of the second dose on long term rubella immunity cannot be predicted at this time. These data also underscore the continuing need for prenatal rubella screening program.

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