Effect of nystatin, amphotericin B and amphotericin B methyl ester on Saccharomyces cerevisiae with different lipid composition

1990 ◽  
Vol 112 (3) ◽  
pp. 165-172 ◽  
Author(s):  
Maria Aperecida de Resende ◽  
Flávio Alterhum
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Methyl Ester ◽  
Amphotericin B ◽  
Lipid Composition ◽  
Amphotericin B Methyl Ester

scholarly journals Comparative studies on cell stimulatory, permeabilizing and toxic effects induced in sensitive and multidrug resistant fungal strains by amphotericin B (AMB) and N-methyl-N-D-fructosyl amphotericin B methyl ester (MFAME).

2000 ◽  
Vol 47 (1) ◽  
pp. 133-140 ◽  
Author(s):  
J Szlinder-Richert ◽  
B Cybulska ◽  
J Grzybowska ◽  
E Borowski ◽  
R Prasad
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Methyl Ester ◽  
Amphotericin B ◽  
Mammalian Cells ◽  
Parent Compound ◽  
Multidrug Resistant ◽  
Solubility In Water ◽  
Good Solubility ◽  
Low Toxicity ◽  
Amphotericin B Methyl Ester

N-Methyl-N-D-fructosyl-amphotericin B methyl ester (MFAME) is a new derivative of amphotericin B, which is characterised by low toxicity to mammalian cells and good solubility in water of its salts. The antifungal activity and effects of MFAME towards Candida albicans and Saccharomyces cerevisiae multidrug resistant MDR(+) and sensitive MDR(-) strains was compared with those of parent compound. The results obtained indicate that MDR(+) S. cerevisiae was sensitive to MFAME as well as to AMB. MFAME exhibited the same effects on fungal cells studied as parent antibiotic. The two antibiotics, depending on the dose applied induced cell stimulation, K+ efflux, and/or had a toxic effect.

Subchronic Toxicity Studies of N-D-Ornithyl Amphotericin B Methyl Ester in Dogs and Rats

1985 ◽  
Vol 5 (4) ◽  
pp. 737-753
Author(s):  
TOBIAS MASSA ◽  
DINESH P. SINHA ◽  
JERRY D. FRANTZ ◽  
MARY E. FILIPEK ◽  
RAYMOND C. WEGLEIN ◽  
...  
Keyword(s):  
Methyl Ester ◽  
Amphotericin B ◽  
Subchronic Toxicity ◽  
Toxicity Studies ◽  
Amphotericin B Methyl Ester

The Perpendicular Orientation of Amphotericin B Methyl Ester in Hydrated Lipid Bilayers Supports the Barrel-Stave Model

Biochemistry ◽  
2019 ◽  
Vol 58 (17) ◽  
pp. 2282-2291 ◽  
Author(s):  
Tomoya Yamamoto ◽  
Yuichi Umegawa ◽  
Masaki Yamagami ◽  
Taiga Suzuki ◽  
Hiroshi Tsuchikawa ◽  
...  
Keyword(s):  
Methyl Ester ◽  
Amphotericin B ◽  
Lipid Bilayers ◽  
Perpendicular Orientation ◽  
Amphotericin B Methyl Ester

Stereoselective syntheses of the 14-hydroxy epimers of amphotericin B methyl ester

1993 ◽  
pp. 1829 ◽  
Author(s):  
Benjamin J. Costello ◽  
Michael J. Driver ◽  
William S. MacLachlan ◽  
Andrew W. Taylor
Keyword(s):  
Methyl Ester ◽  
Amphotericin B ◽  
Amphotericin B Methyl Ester ◽  
Stereoselective Syntheses

Relationship between the antibiotic and immunoadjuvant effects of amphotericin B methyl ester

1978 ◽  
Vol 15 (4) ◽  
pp. 219-224 ◽  
Author(s):  
J. Russell Little ◽  
Edeltraut J. Plut ◽  
Janina Kotler-Brajtburg ◽  
Gerald Medoff ◽  
George S. Kobayashi
Keyword(s):  
Methyl Ester ◽  
Amphotericin B ◽  
Amphotericin B Methyl Ester

Enhancement of Viral RNA-Induced Interferon Production in L Cells Treated with Insulin and Amphotericin B Methyl Ester

1981 ◽  
Vol 1 (4) ◽  
pp. 581-586 ◽  
Author(s):  
DAVID J. GIRON ◽  
KATHERINE C. SMITH ◽  
JANIS A. HOFFMAN ◽  
ARNOLD K. FOWLER
Keyword(s):  
Methyl Ester ◽  
Amphotericin B ◽  
Viral Rna ◽  
Interferon Production ◽  
L Cells ◽  
Amphotericin B Methyl Ester
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