Ascorbic acid as a reducing agent in quantitative analysis

1955 ◽  
Vol 147 (5) ◽  
pp. 338-347 ◽  
Author(s):  
G. Gopala Rao ◽  
V. Narayana Rao
Keyword(s):  
Ascorbic Acid ◽  
Quantitative Analysis ◽  
Reducing Agent

Ascorbic acid as a reducing agent in quantitative analysis

1956 ◽  
Vol 150 (1) ◽  
pp. 29-39 ◽  
Author(s):  
G. Gopala Rao ◽  
U. Veereswara Rao
Keyword(s):  
Ascorbic Acid ◽  
Quantitative Analysis ◽  
Reducing Agent

A profluorescent nitroxide probe for ascorbic acid detection and its application to quantitative analysis of diabetic rat plasma

RSC Advances ◽  
2016 ◽  
Vol 6 (65) ◽  
pp. 60907-60915 ◽  
Author(s):  
Yuta Matsuoka ◽  
Kei Ohkubo ◽  
Toshihide Yamasaki ◽  
Mayumi Yamato ◽  
Hiroshi Ohtabu ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Quantitative Analysis ◽  
Rat Plasma ◽  
Diabetic Rat ◽  
Nitroxide Probe ◽  
Ascorbic Acid Detection

15-((9-(Ethylimino)-10-methyl-9Hbenzo[a]phenoxazin-5-yl)amino)-3,11-dioxa-7-azadispiro[5.1.58.36]hexadecan-7-yloxyl, (Nile-DiPy) has been synthesized and examined as an off–on profluorescent nitroxide probe for measuring ascorbic acid in plasma.

scholarly journals Iodometric Quantitative Analysis Method of Ascorbic Acid in Tablets

2019 ◽  
Vol 70 (10) ◽  
pp. 3555-3560
Author(s):  
Costinela Valerica Georgescu ◽  
Cristian Catalin Gavat ◽  
Doina Carina Voinescu
Keyword(s):  
Ascorbic Acid ◽  
Quantitative Analysis ◽  
Standard Deviation ◽  
Statistical Significance ◽  
The Body ◽  
Water Soluble ◽  
International Standards ◽  
Titration Method ◽  
Normal Limits ◽  
Relative Standard

Ascorbic acid is a water-soluble vitamin provided with strong antioxidant action, that fulfills an important immune protective role of the body against infections and prevents various cancers appearance. The main goal of this study was to exactly quantify pure ascorbic acid in tablets of two pharmaceuticals. Proposed objective consisted in improvement and application of a iodometric titration method in ascorbic acid quantitative analysis. Ascorbic acid content per tablet in both studied pharmaceuticals was 173.84 mg, very close to official stated amount of active substance (180 mg). Allowed percentage deviation from declared content of pure ascorbic acid was only 3.42 %, below maximum value of � 5 % imposed by Romanian Pharmacopoeia 10-th Edition, according to European and International standards. Statistical analysis confirmed experimental obtained results and revealed low Standard Error value SE = 0.214476, which has fallen within normal limits. Confidence Level value (95.0 %) = 0.551328 and Standard Deviation SD = 0.525357. were within normal range of values. Relative Standard Deviation (Coefficient of variation or homogeneity) RSD = 26.268% was found below maximum range of accepted values (30-35%). P value = 7.44. 10-6 was located within normal limits, P [ 0.001, so the experimental obtained results has shown highest statistical significance. Thus, studied titration method can be successfully used in quantitative analysis of ascorbic acid from different samples.

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