Human skeletal muscle debranching enzyme activities with exercise and training

1974 ◽  
Vol 33 (4) ◽  
pp. 327-330 ◽  
Author(s):  
A. W. Taylor ◽  
J. Stothart ◽  
R. Thayer ◽  
M. Booth ◽  
S. Rao
1972 ◽  
Vol 50 (5) ◽  
pp. 411-415 ◽  
Author(s):  
A. W. Taylor ◽  
R. Thayer ◽  
S. Rao

A 5 month training program increased skeletal muscle glycogen synthetase activities of both the 'I' and 'D' forms in human subjects. The level of activity of the enzyme appears to be directly related to the physical fitness level of the subjects tested.


2003 ◽  
Vol 89 (1) ◽  
pp. 119-127 ◽  
Author(s):  
Jørn Wulff Helge ◽  
Agnieszka Dobrzyn ◽  
Bengt Saltin ◽  
Jan Gorski

2012 ◽  
Vol 590 (3) ◽  
pp. 595-606 ◽  
Author(s):  
B. Hoier ◽  
N. Nordsborg ◽  
S. Andersen ◽  
L. Jensen ◽  
L. Nybo ◽  
...  

2005 ◽  
Vol 57 (3) ◽  
pp. 331-335 ◽  
Author(s):  
Jan J Kaczor ◽  
Wieslaw Ziolkowski ◽  
Jerzy Popinigis ◽  
Mark A Tarnopolsky

2004 ◽  
Vol 32 ◽  
pp. 11-25
Author(s):  
J L L Rivero

The skeletal musculature of the horse is highly developed and adapted to match the animal's athletic potential. More than half of a mature horse's body weight comprises skeletal muscle and the total muscle blood flow during maximal exercise represents 78% of total cardiac output. Exercise requires the co–ordinated application of many different body systems under the control of the nervous systems. Metabolites and oxygen reach skeletal muscle fibres via the respiratory, cardiovascular and haematological systems. The muscle fibres produce energy in the form of ATP that, via the contractile machinery, is converted into mechanical work. The structural arrangements of the musculoskeletal system provides the means with which to harness this energy to move the horse's limbs in a characteristic rhythmical pattern that is well established for each gait.Equine skeletal muscle is considerably heterogeneous and this diversity reflects functional specialisation and is the basis of its adaptive plasticity. Cellular and molecular diversity of equine muscle and the response of this tissue to exercise and training have been studied extensively over the past 30 years.


1989 ◽  
Vol 258 (3) ◽  
pp. 911-913 ◽  
Author(s):  
K Sahlin ◽  
S Broberg ◽  
A Katz

Eight men exercised at 66% of their maximal isometric force to fatigue after prior decrease in the glycogen store in one leg (low-glycogen, LG). The exercise was repeated with the contralateral leg (control) at the same relative intensity and for the same duration. Muscle (quadriceps femoris) glycogen content decreased in the LG leg from 199 +/- 17 (mean +/- S.E.M.) to 163 +/- 16 mmol of glucosyl units/kg dry wt. (P less than 0.05), and in the control leg from 311 +/- 23 to 270 +/- 18 mmol/kg (P less than 0.05). The decrease in glycogen corresponded to a similar accumulation of glycolytic intermediates. Muscle glucose increased in the LG leg during the contraction, from 1.8 +/- 0.1 to 4.3 +/- 0.6 mmol/kg dry wt. (P less than 0.01), whereas no significant increase occurred in the control leg (P greater than 0.05). It is concluded that during exercise glucose is formed from glycogen through the debranching enzyme when muscle glycogen is decreased to values below about 200 mmol/kg dry wt.


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