Regulation of the central metabolism in relation to citric acid production in Saccharomycopsis lipolytica

1977 ◽  
Vol 113 (1-2) ◽  
pp. 99-104 ◽  
Author(s):  
R�my Marchal ◽  
Jean-Paul Vandecasteele ◽  
Maurice Metche
Keyword(s):  
Citric Acid ◽  
Acid Production ◽  
Citric Acid Production ◽  
Central Metabolism ◽  
Saccharomycopsis Lipolytica

Isolation and characterization of a Saccharomycopsis lipolytica mutant showing increased production of citric acid from canola oil

1985 ◽  
Vol 31 (5) ◽  
pp. 436-440 ◽  
Author(s):  
David W. Good ◽  
Randal Droniuk ◽  
G. Ross Lawford ◽  
Jared E. Fein
Keyword(s):  
Citric Acid ◽  
Canola Oil ◽  
Acid Production ◽  
Phosphoenolpyruvate Carboxykinase ◽  
Citric Acid Production ◽  
Isocitric Acid ◽  
Isolation And Characterization ◽  
Saccharomycopsis Lipolytica ◽  
Acid Ratio

A process for the production of citric acid from canola (rapeseed) oil using the yeast Saccharomycopsis lipolytica was examined. A citrate nonutilizing strain, designated NTG9, which had an improved citric to isocitric acid ratio, was isolated after mutagenesis of S. lipolytica ATCC 20228 with nitrosoguanidine. Although the mutant grew well on canola oil, unlike the parent strain or a spontaneous revertant (JF2), it did not grow on glycolytic intermediates below glycerate-3-phosphate, amino acids, hexadecane, or yellow kerosene. The mutant was shown to be impaired in the gluconeogenic pathway because of a loss of phosphoenolpyruvate carboxykinase activity. A preliminary study of the effect of micronutrients on citric acid production by S. lipolytica NTG9 showed that manganese had a stimulatory effect on the process whereas zinc and iron were inhibitory. A revised growth medium was tested and found to increase citric acid production while decreasing that of isocitric acid.

scholarly journals The Effect of Lipids on Citric Acid Production by an Aspergillus niger Mutant

1963 ◽  
Vol 30 (3) ◽  
pp. 365-379 ◽  
Author(s):  
N. F. MILLIS ◽  
B. H. TRUMPY ◽  
B. M. PALMER
Keyword(s):  
Citric Acid ◽  
Aspergillus Niger ◽  
Acid Production ◽  
Citric Acid Production

scholarly journals Experimental Design as a Tool for the Development of Citric Acid Production by Yarrowia lipolytica Using Glycerol as a Feedstock

2013 ◽  
Vol 3 (8) ◽  
Author(s):  
Luana V. da Silva ◽  
Camila B. Tavares ◽  
Roberta dos R. Ribeiro ◽  
Fernando L. P. Pessoa ◽  
Maria Alice Z. Coelho ◽  
...  
Keyword(s):  
Citric Acid ◽  
Experimental Design ◽  
Yarrowia Lipolytica ◽  
Acid Production ◽  
Citric Acid Production

scholarly journals Determination of Optimum Composition of Fermentation Medium for Citric Acid Production from Watermelon Rinds using Response Surface Methodology

2017 ◽  
Vol 1 (1) ◽  
pp. 12-16
Author(s):  
Andrew Amenaghawon ◽  
◽  
Oluwatoba Salokun ◽  
Justina Okhonmina ◽  
Imuetinyan Egharevba ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Citric Acid ◽  
Response Surface ◽  
Acid Production ◽  
Fermentation Medium ◽  
Optimum Composition ◽  
Citric Acid Production
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