Interaction among scopolamine, conditioned stimulus modality, genotype, and either-way avoidance behavior of rats

1980 ◽  
Vol 67 (1) ◽  
pp. 97-99 ◽  
Author(s):  
K. Paul Satinder
1967 ◽  
Vol 20 (1) ◽  
pp. 199-205 ◽  
Author(s):  
Donald F. Caldwell ◽  
Edward F. Domino

Albino rats ( N = 200) required progressively more time per trial to perform a previously learned response to obtain food reward than saline and untreated controls following administration of increasing doses of LSD-25 (100, 200, 400 μg/kg). Ss conditioned to respond to a light stimulus showed more response decrement than animals cued by an auditory stimulus for increasing LSD-25 levels. Within each stimulus modality, a greater response decrement was observed following administration of LSD-25 for the higher intensity stimulus value for all but one treatment group. Results were discussed in relation to reports of sensitization and sensory blockage actions for LSD-25.


2018 ◽  
Vol 123 (2) ◽  
pp. 224-238 ◽  
Author(s):  
Yusuke Nitta ◽  
Toru Takahashi ◽  
Tomosumi Haitani ◽  
Eriko Sugimori ◽  
Hiroaki Kumano

Several studies have revealed that fear recovery is prevented when extinction training is conducted after retrieval of a fear memory. Postretrieval extinction training is related to modification of memory during reconsolidation. Providing new information during reconsolidation can modify the original memory. We propose that avoidance behavior is a relevant factor that prevents subjects from obtaining new safety information during reconsolidation. Postretrieval extinction training without avoidance behavior reduced the fear response to conditioned stimulus and prevented spontaneous recovery in the current study, which corresponded with previous studies. Under the condition of postretrieval extinction training with avoidance behavior, the fear response was not reduced as much as it was in the condition without avoidance. It is possible that avoidance behavior prevents receiving new safety information during postretrieval extinction training.


1975 ◽  
Vol 14 (2) ◽  
pp. 211-216 ◽  
Author(s):  
Robert S. Dyer ◽  
Milton A. Hammond ◽  
Douglas A. Weldon ◽  
Thomas C. Booker

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