CYP3–15: An up-promoter mutation at the ISO-2 cytochrome c structural gene locus and its interaction with other independent regulatory mutations of cytochrome c synthesis in Saccharomyces cerevisiae

1979 ◽  
Vol 175 (2) ◽  
pp. 209-216 ◽  
Author(s):  
Jacqueline Verdière ◽  
Eric Petrochilo
Genetics ◽  
1978 ◽  
Vol 89 (4) ◽  
pp. 653-665
Author(s):  
Arjun Singh ◽  
Fred Sherman

ABSTRACT Some of the deletions in the yeast Saccharomyces cerevisiae that encompass the CYC1 gene, which determines iso-1-cytochrome c, extend into the OSM1 gene, causing inhibition of growth on hypertonic media, and into the RAD7 gene, causing sensitivity to UV light. Two deletions (cyc1-363 and cyc1-367) encompass only the CYC1 gene, two deletions (cyc1-366 and cyc1-368) encompass the CYC1 and OSM1 genes, three deletions (cyc1-1, cyc1-364 and cyc1-365) encompass the CYC1, OSM1 and RAD7 genes, while none of the deletions extend into the closely linked SUP4 gene.


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