New amino acids, and heterocyclic compounds participating in the stickland reaction of Clostridium sticklandii

1973 ◽  
Vol 93 (3) ◽  
pp. 267-276 ◽  
Author(s):  
Arnold C. Schwartz ◽  
Reinhold Sch�fer
Keyword(s):  
Amino Acids ◽  
Heterocyclic Compounds ◽  
Stickland Reaction ◽  
Clostridium Sticklandii

scholarly journals Recent Applications of Carbon‐Nitrogen Lyases in Asymmetric Synthesis of Noncanonical Amino Acids and Heterocyclic Compounds

ChemBioChem ◽  
2020 ◽  
Vol 21 (19) ◽  
pp. 2733-2742 ◽  
Author(s):  
Jielin Zhang ◽  
Mohammad Z. Abidin ◽  
Thangavelu Saravanan ◽  
Gerrit J. Poelarends
Keyword(s):  
Amino Acids ◽  
Asymmetric Synthesis ◽  
Heterocyclic Compounds ◽  
Noncanonical Amino Acids

scholarly journals PROSPECTS FOR CREATING RADON CONTAINING AGENTS IN RADIONUCLIDE THERAPY

2021 ◽  
Vol 93 (3) ◽  
pp. 64-72
Author(s):  
E. A. Dikusar ◽  
A.L. Pushkarchuk ◽  
T.V. Bezyazychnaya ◽  
E.A. Akishina ◽  
A.G. Soldatov ◽  
...  
Keyword(s):  
Amino Acids ◽  
Electronic Structure ◽  
Quantum Chemical ◽  
Radionuclide Therapy ◽  
Heterocyclic Compounds ◽  
The Body ◽  
Quantum Chemical Simulation ◽  
Nucleic Bases ◽  
Oncological Diseases ◽  
Chemical Simulation

One of the methods for treating oncological diseases is application of short-lived radionuclides. Existing risks of intoxication and radioactive contamination can be eliminated by introduction of a short-lived radon isotope into a hard strong fullerene coat. To increase the effectiveness of these drugs it is promising to introduce structural fragments of amino acids, peptides, steroid hormones, nucleic bases or heterocyclic compounds being able to accumulate exactly in tumoral but not in healthy tissues of the body. The article presents data on quantum-chemical simulation of electronic structure and thermodynamic stability of fullerenol radon-containing agents of radionuclide therapy on the example of a model cortisonefullerenol bioconjugate.

Effect of phospholipid on the formation of volatile heterocyclic compounds in heated aqueous solutions of amino acids and ribose

1988 ◽  
Vol 42 (3) ◽  
pp. 261-272 ◽  
Author(s):  
Frank B. Whitfield ◽  
Donald S. Mottram ◽  
Susan Brock ◽  
David J. Puckey ◽  
Linda J. Salter
Keyword(s):  
Amino Acids ◽  
Aqueous Solutions ◽  
Heterocyclic Compounds

scholarly journals Influence of 1-[(E)-2-(2-Methyl-4-Nitrophenyl)Diaz-1-enyl]Pyrrolidine-2-Carboxylic Acid and Diphenyliodonium Chloride on Ruminal Protein Metabolism and Ruminal Microorganisms

1999 ◽  
Vol 65 (7) ◽  
pp. 3258-3260 ◽  
Author(s):  
Fabienne Floret ◽  
Lal C. Chaudhary ◽  
William C. Ellis ◽  
Suliman El Hassan ◽  
Nest McKain ◽  
...  
Keyword(s):  
Amino Acids ◽  
Carboxylic Acid ◽  
High Activity ◽  
Protein Metabolism ◽  
Microbial Population ◽  
Ruminal Microorganisms ◽  
Clostridium Sticklandii ◽  
Grass Hay

ABSTRACT The effects of 1-[(E)-2-(2-methyl-4-nitrophenyl)diaz-1-enyl]pyrrolidine-2-carboxylic acid (LY29) and diphenyliodonium chloride (DIC) on the degradation of protein to ammonia were determined in a mixed rumen microbial population taken from sheep on a grass hay-concentrate diet. Both compounds decreased NH3 production by inhibiting deamination of amino acids. LY29, but not DIC, inhibited growth of the high-activity ammonia-producing species, Clostridium aminophilum and Clostridium sticklandii.

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