Effect of Prostaglandin E2 on aqueous humor flow in the rabbit eye

1974 ◽  
Vol 190 (3) ◽  
pp. 221-227 ◽  
Author(s):  
Stephen Tak�ts ◽  
Casimir Jobst ◽  
Hilda Szilv�ssy
Keyword(s):  
Prostaglandin E2 ◽  
Aqueous Humor ◽  
Rabbit Eye ◽  
Aqueous Humor Flow

Numerical Simulation of Multi-Field Coupling in Aqueous Humor Under the Condition of Dynamic Pressure

2019 ◽  
Vol 16 (03) ◽  
pp. 1842001 ◽  
Author(s):  
Hongfang Song ◽  
Lin Li ◽  
Wenjia Wang ◽  
Qi Li ◽  
Zhicheng Liu
Keyword(s):  
Numerical Simulation ◽  
Aqueous Humor ◽  
Dynamic Pressure ◽  
Field Coupling ◽  
Rabbit Eye ◽  
Aqueous Humor Flow ◽  
Simulation Based ◽  
Dynamic Pressure Measurement ◽  
Ocular Pressure ◽  
Fluid Solid Interaction

In order to investigate the aqueous humor flow based on the coupling effects of fluid–solid–heat under different ocular pressure, four models of rabbit eye were constructed and multi-field coupling vs. fluid–solid interaction was compared in these models. ADINA software was applied to mimic the aqueous humor flow. The contour of temperature demonstrates multiple peaks with larger value near the pupil. The flow pattern is influenced mainly by the variation of ocular pressure. It is necessary to perform multi-field coupling simulation based on dynamic pressure measurement when studying the aqueous humor flow in eyes.

The Arterially Perfused Enucleated Rabbit Eye as a Model for Studying Aqueous Humor Formation

1983 ◽  
Vol 15 (5) ◽  
pp. 225-233 ◽  
Author(s):  
T. Kodama ◽  
V.N. Reddy ◽  
F.J. Macri
Keyword(s):  
Aqueous Humor ◽  
Rabbit Eye

5-Methylurapidil, 8-Iso Prostaglandin E2: New Drugs to Increase Aqueous-Humor Outflow Facility

2000 ◽  
pp. 253-259
Author(s):  
J. B. Serle ◽  
S. M. Podos ◽  
R.-F. Wang ◽  
T. Mittag ◽  
P.-Y. Lee ◽  
...  
Keyword(s):  
Prostaglandin E2 ◽  
Aqueous Humor ◽  
New Drugs ◽  
Outflow Facility ◽  
Aqueous Humor Outflow

Numerical simulation of the aqueous humor flow in the eye drainage system; a healthy and pathological condition comparison.

2020 ◽  
Vol 83 ◽  
pp. 82-92 ◽  
Author(s):  
G.J. Martínez Sánchez ◽  
C. Escobar del Pozo ◽  
J.A. Rocha Medina ◽  
J. Naude ◽  
A. Brambila Solorzano
Keyword(s):  
Numerical Simulation ◽  
Aqueous Humor ◽  
Pathological Condition ◽  
Drainage System ◽  
Aqueous Humor Flow ◽  
System A

Growth factor-like phospholipids generated after corneal injury

1998 ◽  
Vol 274 (4) ◽  
pp. C1065-C1074 ◽  
Author(s):  
Károly Liliom ◽  
Zhiwei Guan ◽  
Jih-Lie Tseng ◽  
Dominic M. Desiderio ◽  
Gábor Tigyi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Growth Factor ◽  
Phosphatidic Acid ◽  
Aqueous Humor ◽  
Lysophosphatidic Acid ◽  
Xenopus Oocyte ◽  
Two Dimensional ◽  
Corneal Injury ◽  
Rabbit Eye ◽  
Cellular Regeneration

The present study provides evidence that growth factor-like glycerophosphate mediators of the lysophosphatidic acid (LPA) family are present in the aqueous humor and the lacrimal gland fluid of the rabbit eye. By use of a combination of HPLC, two-dimensional TLC, mass spectrometry, and the Xenopus oocyte bioassay, the LPA-like phospholipids LPA, cyclic PA, alkenyl-glycerophosphate (GP), lysophosphatidylserine, and phosphatidic acid were detected as physiological constituents of the fluids bathing the cornea. Corneal injury resulted in an increased production of some of these mediators. Alkenyl-GP, a novel member of the LPA family, has been identified in postinjury aqueous humor, establishing that it is generated endogenously. LPA and its homologues were found to be mitogenic in freshly dissociated keratocytes from uninjured corneas. There appears to be a link between the occurrence of LPA responsiveness in keratocytes activated by injury and the increase in LPA-like activity in aqueous humor. These data suggest that LPA and its homologues are involved in maintaining the integrity of the normal cornea and in promoting cellular regeneration of the injured cornea.

Potential errors in measuring aqueous humor flow

1992 ◽  
Vol 55 ◽  
pp. 213 ◽  
Author(s):  
J.W. McLaren ◽  
R.F. Brubaker
Keyword(s):  
Aqueous Humor ◽  
Aqueous Humor Flow
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