Comparative study of tumorigenicity in mice administered transplacentally or neonatally with metabolites of tryptophan and its related compounds

1980 ◽  
Vol 96 (2) ◽  
pp. 163-168 ◽  
Author(s):  
K. Fujii ◽  
M. Watanabe
2017 ◽  
Vol 12 (2) ◽  
pp. 1934578X1701200
Author(s):  
Teisa Tufa ◽  
Harilaos Damianakos ◽  
Konstantia Graikou ◽  
Ioanna Chinou

The cyclohexane (Ch) extracts of the roots of five Greek endemic Boraginaceae plants, Onosma kaheirei Teppner, O. graeca Boiss., O. erecta Sibth. & Sm., Alkanna sfikasiana Kit Tan, Vold and Strid and Cynoglossum columnae Ten, were investigated for the presence of alkannin/shikonin-related compounds. All species, s except C. columnae and O. erecta, were found to contain this type of compounds. Seven compounds were obtained after several chromatographic separations from the Ch extracts of the investigated plants: deoxyalkannin (1), 2″-( S)- α-methylbutyrylalkannin (2), isobutyrylalkannin (3), propionylalkannin (4), acetylalkannin (5), β-hydroxyisovalerylalkannin (6), and β,β-dimethylacrylalkannin (7). All structures were identified by 1D 1H-/13C- and 2D NMR spectroscopy, assisted also by ESI-MS. The extracts and the isolated compounds exhibiting an interesting antimicrobial profile when evaluated for their antimicrobial activity against six Gram-positive and -negative bacteria and three human pathogenic fungi.


1969 ◽  
Vol 47 (5) ◽  
pp. 723-727 ◽  
Author(s):  
J. M. Pepper ◽  
Y. W. Lee

A detailed comparative study has been made of the effectiveness of various catalysts for the hydrogenolysis of spruce wood lignin. The catalysts studied were Raney nickel, 10% palladium–charcoal, 5% rhodium–charcoal, 5% rhodium–alumina, 5% ruthenium–charcoal, and 5% ruthenium–alumina. Lignin degradation products were obtained initially as a chloroform-soluble fraction which was then divided and studied as diethyl ether-soluble and -insoluble fractions. Gas–liquid chromatographic separation of the ether-soluble fraction made possible the characterization and quantitative estimation of many of the lower molecular weight lignin degradation products.The data indicate that rhodium, palladium, and a limited amount of Raney nickel produce similar results as do ruthenium and an excess of Raney nickel; however, with the latter catalysts the degradation is more severe. In particular, rhodium–charcoal and palladium–charcoal appear to offer interesting advantages as catalysts for lignin hydrogenolysis.


2007 ◽  
Vol 45 (9) ◽  
pp. 1770-1776 ◽  
Author(s):  
Yerra Koteswara Rao ◽  
Madamanchi Geethangili ◽  
Shih-Hua Fang ◽  
Yew-Min Tzeng

Sign in / Sign up

Export Citation Format

Share Document