scholarly journals Hearing impairment in WBN/Kob rats with spontaneous diabetes mellitus

Diabetologia ◽  
1995 ◽  
Vol 38 (6) ◽  
pp. 649-655 ◽  
Author(s):  
T. Ishikawa ◽  
Y. Naito ◽  
K. Taniguchi
Keyword(s):  
Diabetes Mellitus ◽  
Hearing Impairment ◽  
Spontaneous Diabetes

scholarly journals Hearing impairment in WBN/Kob rats with spontaneous diabetes mellitus

Diabetologia ◽  
1995 ◽  
Vol 38 (6) ◽  
pp. 649-655 ◽  
Author(s):  
T. Ishikawa ◽  
Y. Naito ◽  
K. Taniguchi
Keyword(s):  
Diabetes Mellitus ◽  
Hearing Impairment ◽  
Spontaneous Diabetes

Hearing impairment in nigerians with type 2 diabetes mellitus attending fmc Lokoja

2018 ◽  
Author(s):  
Adewole Adesanya ◽  
Stephen Ogah ◽  
Olorunfemi Adebayo ◽  
Palma Ogbeide ◽  
Majekodunmi Agbona ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Hearing Impairment

scholarly journals Correlation Analysis Study between Hearing Loss Occurence and Duration of Type 2 Diabetes Mellitus in Sultan Agung Islamic Hospital Semarang

Sains Medika ◽  
2015 ◽  
Vol 6 (1) ◽  
pp. 12
Author(s):  
Citta Arunika Risyudhanti ◽  
Agung Sulistyanto ◽  
Suparmi Suparmi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Hearing Impairment ◽  
Medical Records ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Chi Square ◽  
Cross Sectional

Introduction: Hearing impairment due to cochlear damage is one complication of Type 2 Diabetes Mellitus (DM2). Objective: This study aims to determine the relationship between duration of DM2 with hearing impairment.Method: The analytic observasional study with the cross sectional design using the medical record of DM2 outpatient in internal clinic of Islamic Sultan Agung Hospital Semarang and also pure tone audiometric examination’s record in Otorynolaryngology clinic of Islamic Sultan Agung Hospital Semarang.31 medical records of DM2 patients were meeting the inclusion and exclusion criteria. The data consist of 18 medical records of patients with less than6 years duration of DM2, and 13 medical records of patients with more than 6 years duration of DM2. The pure tone audiometry was used to classified the hearing impairment. The data analysis was conducted using SPSS 20.0. The correlation between the duration of DM2 and hearing impairment was analyzed using Chi Square test. The significance relation between the duration of DM type 2 and hearing impairment was analyzed using cooficient contigency, with significance of < 0.05. Result: hearing impairment’s distribution frequency on tested ears in Sultan agung Islamic Hospital Semarang were 27 ears having SNHL type (43,5%), 19 ears having CHL (30,6%) and 16 ears were normal (25,8%), p = 0,02 (p < 0,05). Conclusion: There is a weak correlation between the DM 2 duration and the incidence of hearing impairment in Sultan Agung Islamic Hospital Semarang.

scholarly journals Prevalência de perda auditiva, e fatores associados, em pacientes com doença renal crônica em tratamento conservador

HU Revista ◽  
2020 ◽  
Vol 46 ◽  
pp. 1-9
Author(s):  
Monik Assis Espindula Mota ◽  
Jose Otávio do Amaral Corrêa ◽  
Renato Erothildes Ferreira ◽  
Matheus Rodrigues Mendes Moraes ◽  
Bruno Parisi Marlière ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Hearing Impairment ◽  
Population Based ◽  
Hearing Disorders ◽  
Ear Diseases ◽  
Tnf Α ◽  
Ifn Γ ◽  
Survey Protocol ◽  
Population Based Survey

Introdução: A perda auditiva (PA) é uma condição cada vez mais observada na população. É encontrada com maior frequência em alguns grupos específicos como em idosos, portadores de hipertensão arterial sistêmica e diabetes mellitus. Evidências sugerem aumento da prevalência de PA em pacientes com doença renal crônica (DRC), entretanto estudos na população brasileira com DRC pré-dialítica são escassos. Objetivo: Avaliar a prevalência de perda auditiva em uma população de pacientes com doença renal crônica não dialítica e fatores associados. Material e métodos: Foi utilizada uma amostra por conveniência de pacientes com DRC não dialítica (n=159), com idade de 18 a 65 anos, em tratamento ambulatorial multidisciplinar. A acuidade auditiva foi avaliada pela audiometria tonal limiar e pelo questionário da WHO (Ear and Hearing Disorders Survey Protocol for a Population-Based Survey of Prevalence and Causes of Deafness and Hearing Impairment and other Ear Diseases) traduzido e validado para o português. Foram coletados dados sociodemográficos e clínicos, realizada ainda otoscopia, e dosagem de marcadores bioquímicos e citocinas inflamatórias TNF-α, IFN-γ, IL-1β, IL-6, IL-10, IL-17. Resultados: Nas análises, verificou-se a prevalência de 25,16% de perda auditiva neurossensorial entre os participantes. No estudo, não foi encontrada nenhuma associação entre a progressão dos estágios da DRC e o aumento de prevalência da PA, tampouco com a sua gravidade. Os marcadores sanguíneos avaliados, isoladamente ou associados à progressão do estágio da DRC, não se relacionaram à perda auditiva neurossensorial. Conclusões: Verifica-se que a prevalência de déficit auditivo na população estudada foi de 25,16%. Aconselha-se que estratégias sejam implementadas para prevenção e reversão dessa situação nesta população.  

Mechanisms of cyclosporine protection against spontaneous diabetes mellitus in the BB/Wor rat

1989 ◽  
Vol 2 (2) ◽  
pp. 133-150 ◽  
Author(s):  
Hernan Baquerizo ◽  
John Leone ◽  
Clifford Pukel ◽  
Peter Wood ◽  
Alexander Rabinovitch
Keyword(s):  
Diabetes Mellitus ◽  
Spontaneous Diabetes

Effect of thalidomide on the incidence of iodine-induced and spontaneous lymphocytic thyroiditis and spontaneous diabetes mellitus in the BB/Wor rat

1990 ◽  
Vol 123 (1) ◽  
pp. 79-83 ◽  
Author(s):  
Wasana Lueprasitsakul ◽  
Susan Abend ◽  
Sharon Alex ◽  
Walter Reinhardt ◽  
Michael C. Appel ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Autoimmune Diseases ◽  
Spontaneous Diabetes ◽  
Insulin Dependent Diabetes Mellitus ◽  
Insulin Dependent Diabetes ◽  
Dependent Diabetes Mellitus ◽  
Lymphocytic Thyroiditis ◽  
Erythema Nodosum Leprosum ◽  
Graft Vs Host Disease ◽  
Insulin Dependent

Abstract. Thalidomide, a derivative of glutamic acid, has immunosuppressive effects and suppresses graft-vs-host disease in the rat and following bone marrow transplantation in man. It is effectively used in the treatment of erythema nodosum leprosum and has a potential therapeutic effect in a variety of autoimmune diseases. In view of these observations, we evaluated the effect of thalidomide on the incidence of spontaneous and iodine-induced lymphocytic thyroiditis and spontaneous insulin dependent diabetes mellitus in the BB/Wor rat. Thalidomide did not suppress the incidence of lymphocytic thyroiditis and serum anti-thyroglobulin antibodies or affect the serum concentrations of T4, T3 and TSH in this rat model. Thalidomide also did not affect the incidence of insulin dependent diabetes mellitus. In contrast to preliminary studies in man and rat demonstrating efficacy in the therapy of autoimmune diseases, thalidomide did not prevent or suppress autoimmune lymphocytic thyroiditis or insulin-dependent diabetes mellitus in the BB/Wor rat.

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