scholarly journals Carbon metabolism of chloroplasts in the dark: Oxidative pentose phosphate cycle versus glycolytic pathway

Planta ◽  
1979 ◽  
Vol 144 (2) ◽  
pp. 193-200 ◽  
Author(s):  
W. M. Kaiser ◽  
J. A. Bassham
Keyword(s):  
Carbon Metabolism ◽  
Pentose Phosphate ◽  
Glycolytic Pathway ◽  
Pentose Phosphate Cycle

scholarly journals Biosynthesis of food constituents: Amino acids: 2. The alanine-valine-leucine, serine-cysteine-glycine, and aromatic and heterocyclic amino acids groups – a review

2011 ◽  
Vol 24 (No. 2) ◽  
pp. 45-58 ◽  
Author(s):  
J. Velíšek ◽  
K. Cejpek
Keyword(s):  
Amino Acids ◽  
Pyruvic Acid ◽  
Calvin Cycle ◽  
Pentose Phosphate ◽  
Review Article ◽  
Glycolytic Pathway ◽  
Glyceric Acid ◽  
Pentose Phosphate Cycle

This review article gives a survey of principal pathways that lead to the biosynthesis of the proteinogenic amino acids of the alanine-valine-leucine group starting with pyruvic acid from the glycolytic pathway and serine-cysteine-glycine group starting with 3-phospho-d-glyceric acid from the glycolytic pathway. A survey is further given to the aromatic and heterocyclic amino acids (phenylalanine, tyrosine, tryptophan, histidine) starting with 3-phosphoenolpyruvic acid from the glycolytic pathway and d-erythrose 4-phosphate, an intermediate in the pentose phosphate cycle and Calvin cycle.  

Glucose metabolism in Pycnoporus cinnabarinus

1978 ◽  
Vol 24 (5) ◽  
pp. 620-622 ◽  
Author(s):  
Emiko Hirono ◽  
Glaci T. Zancan ◽  
Déa Amaral
Keyword(s):  
Glucose Metabolism ◽  
Enzyme Activities ◽  
Pentose Phosphate ◽  
Glycolytic Pathway ◽  
Pycnoporus Cinnabarinus ◽  
Pentose Phosphate Cycle

It was demonstrated by the measurement of enzyme activities and by radiorespirometric assays that the basidiomycete Pycnoporus cinnabarinus metabolizes glucose through the glycolytic pathway and the pentose phosphate cycle.

Thiamine deficiency and the hepatic pentose phosphate cycle

1975 ◽  
Vol 14 (4) ◽  
pp. 384-390 ◽  
Author(s):  
David W. McCandless ◽  
Carol E. Cassidy ◽  
Alison D. Curley
Keyword(s):  
Thiamine Deficiency ◽  
Pentose Phosphate ◽  
Pentose Phosphate Cycle

scholarly journals YvcK of Bacillus subtilis is required for a normal cell shape and for growth on Krebs cycle intermediates and substrates of the pentose phosphate pathway

Microbiology ◽  
2005 ◽  
Vol 151 (11) ◽  
pp. 3777-3791 ◽  
Author(s):  
Boris Görke ◽  
Elodie Foulquier ◽  
Anne Galinier
Keyword(s):  
Bacillus Subtilis ◽  
Pentose Phosphate Pathway ◽  
Carbon Metabolism ◽  
Carbon Sources ◽  
Krebs Cycle ◽  
Normal Growth ◽  
Central Carbon Metabolism ◽  
Pentose Phosphate ◽  
Homologous Protein ◽  
Krebs Cycle Intermediates

The HPr-like protein Crh has so far been detected only in the bacillus group of bacteria. In Bacillus subtilis, its gene is part of an operon composed of six ORFs, three of which exhibit strong similarity to genes of unknown function present in many bacteria. The promoter of the operon was determined and found to be constitutively active. A deletion analysis revealed that gene yvcK, encoded by this operon, is essential for growth on Krebs cycle intermediates and on carbon sources metabolized via the pentose phosphate pathway. In addition, cells lacking YvcK acquired media-dependent filamentous or L-shape-like aberrant morphologies. The presence of high magnesium concentrations restored normal growth and cell morphology. Furthermore, suppressor mutants cured from these growth defects appeared spontaneously with a high frequency. Such suppressing mutations were identified in a transposon mutagenesis screen and found to reside in seven different loci. Two of them mapped in genes of central carbon metabolism, including zwf, which encodes glucose-6-phosphate dehydrogenase and cggR, the product of which regulates the synthesis of glyceraldehyde-3-phosphate dehydrogenase. All these results suggest that YvcK has an important role in carbon metabolism, probably in gluconeogenesis required for the synthesis of cell wall precursor molecules. Interestingly, the Escherichia coli homologous protein, YbhK, can substitute for YvcK in B. subtilis, suggesting that the two proteins have been functionally conserved in these different bacteria.

scholarly journals Metabolic Changes Induced by Deletion of Transcriptional Regulator GCR2 in Xylose-Fermenting Saccharomyces cerevisiae

2020 ◽  
Vol 8 (10) ◽  
pp. 1499
Author(s):  
Minhye Shin ◽  
Soo Rin Kim
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Carbon Source ◽  
Pentose Phosphate Pathway ◽  
Carbon Metabolism ◽  
Transcriptional Regulator ◽  
Central Carbon Metabolism ◽  
Pentose Phosphate ◽  
Metabolic Changes ◽  
Regulatory Systems ◽  
Central Carbon

Glucose repression has been extensively studied in Saccharomyces cerevisiae, including the regulatory systems responsible for efficient catabolism of glucose, the preferred carbon source. However, how these regulatory systems would alter central metabolism if new foreign pathways are introduced is unknown, and the regulatory networks between glycolysis and the pentose phosphate pathway, the two major pathways in central carbon metabolism, have not been systematically investigated. Here we disrupted gcr2, a key transcriptional regulator, in S. cerevisiae strain SR7 engineered to heterologously express the xylose-assimilating pathway, activating genes involved in glycolysis, and evaluated the global metabolic changes. gcr2 deletion reduced cellular growth in glucose but significantly increased growth when xylose was the sole carbon source. Global metabolite profiling revealed differential regulation of yeast metabolism in SR7-gcr2Δ, especially carbohydrate and nucleotide metabolism, depending on the carbon source. In glucose, the SR7-gcr2Δ mutant showed overall decreased abundance of metabolites, such as pyruvate and sedoheptulose-7-phosphate, associated with central carbon metabolism including glycolysis and the pentose phosphate pathway. However, SR7-gcr2Δ showed an increase in metabolites abundance (ribulose-5-phosphate, sedoheptulose-7-phosphate, and erythrose-4-phosphate) notably from the pentose phosphate pathway, as well as alteration in global metabolism when compared to SR7. These results provide insights into how the regulatory system GCR2 coordinates the transcription of glycolytic genes and associated metabolic pathways.

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