Reference values for blood toluene in the occupationally nonexposed general population

1993 ◽  
Vol 65 (3) ◽  
pp. 201-203 ◽  
Author(s):  
Guangzu Wang ◽  
Graziano Maranelli ◽  
Luigi Perbellini ◽  
Giampaolo Guglielmi ◽  
Francesco Brugnone
Keyword(s):  
General Population ◽  
Reference Values ◽  
Blood Toluene

scholarly journals Normal and reference values for cardiovascular magnetic resonance-based pulse wave velocity in the middle-aged general population

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Max J. van Hout ◽  
Ilona A. Dekkers ◽  
Jos J. Westenberg ◽  
Martin J. Schalij ◽  
Ralph L. Widya ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
General Population ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Disease Risk ◽  
Cardiovascular Disease Risk

Abstract Background Aortic stiffness, assessed through pulse wave velocity (PWV), is an independent predictor for cardiovascular disease risk. However, the scarce availability of normal and reference values for cardiovascular magnetic resonance imaging (CMR) based PWV is limiting clinical implementation. The aim of this study was to determine normal and reference values for CMR assessed PWV in the general population. Methods From the 2,484 participants of the Netherlands Epidemiology of Obesity (NEO) study that have available CMR-PWV data, 1,394 participants free from cardiovasculard disease, smokers or treatment for diabetes, hypertension or dyslipidaemia were selected (45–65 years, 51% female). Participants were divided into sex, age and blood pressure (BP) subgroups. Normal values were specified for participants with a BP < 130/80 mmHg and reference values for elevated BP subgroups (≥ 130/80 and < 140/90 mmHg; and ≥ 140/90 mmHg). Differences between groups were tested with independent samples t-test or ANOVA. Due to an oversampling of obese individuals in this study, PWV values are based on a weighted analysis making them representative of the general population. Results Normal mean PWV was 6.0 m/s [95% CI 5.8–6.1]. PWV increased with advancing age and BP categories (both p < 0.001). There was no difference between sex in normal PWV, however in the BP > 140/90 mmHg women had a higher PWV (p = 0.005). The interpercentile ranges were smaller for participants < 55 years old compared to participants ≥ 55 years, indicating an increasing variability of PWV with age. PWV upper limits were particularly elevated in participants ≥ 55 years old in the high blood pressure subgroups. Conclusion This study provides normal and reference values for CMR-assessed PWV per sex, age and blood pressure category in the general population.

scholarly journals Sex-specific reference values and determinants of infra-renal abdominal aortic diameter among women and men from general population

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
F Zhu ◽  
B Arshi ◽  
M Ikram ◽  
R De Knegt ◽  
M Kavousi
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
General Population ◽  
Cardiovascular Risk Factors ◽  
Reference Values ◽  
Aortic Diameter ◽  
Funding Source ◽  
Men And Women ◽  
Abdominal Aortic

Abstract Introduction Abdominal aortic diameter has shown to be a marker of adverse cardiovascular outcomes. Among the non-aneurysmal populations, studies regarding abdominal aortic diameter normal reference values are sparse. Moreover, data regarding the associations between cardiovascular risk factors and aortic diameter among men and women are limited. Purpose To establish age- and sex-specific distribution of the infra-renal abdominal aortic diameters among non-aneurysmal older adults from the general population and to investigate the associations between cardiovascular risk factors and aortic diameters in men and women. Methods From a population-based cohort, 4032 participants (mean age, 67.2 years; 60.4% women) with infra-renal diameter assessment and without history of cardiovascular disease were included. Mean and quantile values of diameters were calculated in different age groups. Multiple linear regression analysis was used to detect the association of cardiovascular risk factors with diameters in men and women. Results The mean crude diameter was larger in men [mean (SD): 19.5 (2.6) mm] compared to women [17.0 (2.4)mm] but after adjustment for body surface area (BSA), the differences were small. There was a non-linear relationship between age and diameter (p&lt;0.001). After 66 years of age, the increase in diameter with increasing age was attenuated. After age 74 years in women and 71 years in men, the relationship between age and infra-renal aortic diameter was no longer statistically significant (Figure). Waist [standardized β (95% CI): 0.02 (0.0–0.04) in women and 0.03 (0.01–0.06) in men] and diastolic blood pressure [0.04 (0.02–0.05) in women and 0.02 (0.0–0.04) in men] were the risk factors for diameters in both sexes. Body mass index [0.02 (0.01–0.09)], systolic blood pressure [−0.01 (−0.02 to −0.01)], smoking status [0.21 (0.02–0.39)], cholesterol [−0.19 (−0.29 to −0.09)], and lipid-lowering medication [−0.47 (−0.71 to −0.23)] were significantly associated with aortic diameter only in women. Conclusion The differences in the crude abdominal aortic diameter between women and men diminished after taking into account the BSA. The abdominal aortic diameter increased steeply with advancing age and up to 66 years of age. However, after 74 years in women and 71 years in men, the diameter values reached a plateau. We also observed sex differences in the associations of cardiovascular risk factors with abdominal aortic diameter. Funding Acknowledgement Type of funding source: Public Institution(s). Main funding source(s): Netherlands Organization for the Health Research and Development (ZonMw); the Research Institute for Diseases in the Elderly (RIDE)

scholarly journals 0860 Pulse Wave Amplitude Drops During Sleep: Reference Values And Clinical Associations In A General Population

SLEEP ◽  
2019 ◽  
Vol 42 (Supplement_1) ◽  
pp. A345-A345
Author(s):  
Camila Hirotsu ◽  
Pedro Marques-Vidal ◽  
Peter Vollenweider ◽  
Monica Betta ◽  
Giulio Bernardi ◽  
...  
Keyword(s):  
General Population ◽  
Reference Values ◽  
Wave Amplitude ◽  
Pulse Wave ◽  
Pulse Wave Amplitude ◽  
Clinical Associations

scholarly journals The EORTC Quality of Life Questionnaire for cancer patients ( QLQ ‐C30): Australian general population reference values

2019 ◽  
Vol 210 (11) ◽  
pp. 499-506 ◽  
Author(s):  
Rebecca Mercieca‐Bebber ◽  
Daniel SJ Costa ◽  
Richard Norman ◽  
Monika Janda ◽  
David P Smith ◽  
...  
Keyword(s):  
Quality Of Life ◽  
General Population ◽  
Cancer Patients ◽  
Reference Values ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
Eortc Quality

scholarly journals General Population Reference Values for the French Version of the EuroQol EQ-5D Health Utility Instrument

2010 ◽  
Vol 13 (5) ◽  
pp. 631-635 ◽  
Author(s):  
Thomas V. Perneger ◽  
Christophe Combescure ◽  
Delphine S. Courvoisier
Keyword(s):  
General Population ◽  
Reference Values ◽  
Health Utility ◽  
French Version ◽  
Utility Instrument

scholarly journals Normal and reference values for MRI-based pulse wave velocity in the middle-aged general population

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
M.J.P Van Hout ◽  
I.A Dekkers ◽  
J.J.M Westenberg ◽  
M.J Schalij ◽  
R De Mutsert ◽  
...  
Keyword(s):  
Blood Pressure ◽  
General Population ◽  
Pulse Wave Velocity ◽  
Wave Velocity ◽  
Reference Values ◽  
Pulse Wave ◽  
Funding Source ◽  
Clinical Implementation ◽  
Research Profile ◽  
Cv Disease

Abstract Background Aortic stiffness, assessed through pulse wave velocity (PWV), is an independent predictor for cardiovascular (CV) risk. However, the scarce availability of normal and reference values for magnetic resonance imaging (MRI) based PWV is limiting clinical implementation. Purpose The aim of this study was to determine normal and reference values for MRI-PWV in the general population. Methods From the 2,484 participants of the NEO study that have available MRI-PWV data, we selected 1,639 participants that were free from CV disease or treatment for diabetes, hypertension or dyslipidaemia (age range 45–65 years, 51% male). Participants were categorized by sex, age and blood pressure (BP) subgroups. Normal values were specified for healthy (&lt;130/80 mmHg) and elevated BP (≥130/80 and &lt;140/90 mmHg) and reference values for high BP (≥140/90 mmHg) subgroups. Differences between groups were tested with either an independent samples t-test or ANOVA. Results Overall mean PWV was 6.5 m/s [95% CI 6.4–6.6]. PWV increased significantly with advancing age and BP categories (both p&lt;0.001). There was no difference in PWV between men and women, however a stronger increasing trend for women above 55 years old was observed (figure). The 95% CI's were smaller for participants &lt;55 years old as compared to participants &gt;55, indicating an increasing variability of PWV with age. The elevated PWV upper limits for the higher blood pressure subgroups are particularly evident in participants above 55 years old. Conclusion This study provides normal and reference values for MRI-assessed PWV per sex, age and blood pressure category. PWV percentiles (10, 25, 50, 75 and 90th) Funding Acknowledgement Type of funding source: Public hospital(s). Main funding source(s): The NEO study is supported by the participating departments, the Division and the Board of Directors of the Leiden University Medical Centre, and by the Leiden University, Research Profile Area “Vascular and Regenerative Medicine”

scholarly journals Pediatric lipid reference values in the general population: The Dutch lifelines cohort study

2018 ◽  
Vol 12 (5) ◽  
pp. 1208-1216 ◽  
Author(s):  
J.W. Balder ◽  
P.J. Lansberg ◽  
M.H. Hof ◽  
A. Wiegman ◽  
B.A. Hutten ◽  
...  
Keyword(s):  
Cohort Study ◽  
General Population ◽  
Reference Values
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