Expression of H-Y antigen unaltered in XY female mice

1986 ◽  
Vol 23 (1) ◽  
pp. 67-68 ◽  
Author(s):  
Willys K. Silvers ◽  
Susan Raab ◽  
Linda L. Washburn ◽  
Eva M. Eicher
Keyword(s):  
Female Mice ◽  
Xy Female

Generation of fertile and fecund F0 XY female mice from XY ES cells

2014 ◽  
Vol 24 (1) ◽  
pp. 19-29 ◽  
Author(s):  
Junko Kuno ◽  
William T. Poueymirou ◽  
Guochun Gong ◽  
Chia-Jen Siao ◽  
Georgia Clarke ◽  
...  
Keyword(s):  
Es Cells ◽  
Female Mice ◽  
Xy Female

XY follicle cells in ovaries of XX—XY female mouse chimaeras

Development ◽  
1988 ◽  
Vol 104 (4) ◽  
pp. 683-688 ◽  
Author(s):  
P.S. Burgoyne ◽  
M. Buehr ◽  
A. McLaren
Keyword(s):  
Female Mouse ◽  
Germ Line ◽  
Follicle Cells ◽  
Cell Type ◽  
Ovarian Cell ◽  
Female Mice ◽  
Xy Female

Oocytes with adhering follicle cells were sampled from ovaries obtained from 11 GPI-1A—GPI-1B chimaeras, comprising 10 females and 1 hermaphrodite. GPI analysis of individual oocytes revealed a marked bias towards the GPI-1B component in the germ line of this chimaeric combination. GPI-1B XY oocytes were identified in the ovary from the hermaphrodite, the bias towards the GPI-1B germ line perhaps helping to counterbalance the normally severe selection against XY oocytes. GPI analysis of follicle cells revealed a much more balanced contribution of the two components to this ovarian cell type. Importantly, GPI-1A follicle cells were identified in more than half the follicles from an XX—XY female in which the GPI-1A component was XY, supporting an earlier conclusion of Ford et al. (1974) that XY cells can contribute to the follicles of XX—XY female mice. It is suggested that XY cells can be recruited to form follicle cells in XX—XY chimaeras when there is a developmental mismatch between the two components, such that an ovary-determining signal produced by the XX component pre-empts the testis-determining action of the Y.

scholarly journals Normal structure and expression of Zfy genes in XY female mice mutant in Tdy

Development ◽  
1990 ◽  
Vol 109 (3) ◽  
pp. 647-653 ◽  
Author(s):  
J. Gubbay ◽  
P. Koopman ◽  
J. Collignon ◽  
P. Burgoyne ◽  
R. Lovell-Badge
Keyword(s):  
Southern Blot ◽  
Y Chromosome ◽  
Blot Analysis ◽  
Southern Blot Analysis ◽  
Normal Structure ◽  
Structural Alterations ◽  
Female Mice ◽  
Testis Determination ◽  
Zfy Genes ◽  
Xy Female

Zfy-1 and Zfy-2 are candidate genes for Tdy, the testis-determining gene in mice. We have analysed these genes in a line of XY female mice that have been shown to be mutated in Tdy. We have used Southern blot analysis to show that the Zfy genes have not undergone any major structural alterations, and have also demonstrated that both genes are transcribed normally from the mutant Y chromosome (Y) in both adult XYY testis and XY female embryonic gonads. The fact that these genes show a normal structure and expression pattern in mice with a Y chromosome known to carry a mutation in Tdy and that mutant embryos develop into females despite Zfy-1 expression, strongly supports other recent evidence that Zfy genes are not directly involved in primary testis determination.

XY female mice express H-Y antigen

1982 ◽  
Vol 3 (3) ◽  
pp. 247-253 ◽  
Author(s):  
Lawrence L. Johnson ◽  
Evelyn L. Sargent ◽  
Linda L. Washburn ◽  
Eva M. Eicher
Keyword(s):  
Female Mice ◽  
Xy Female

Central forebrain Fos responses to familiar male odours are attenuated in recently mated female mice

2001 ◽  
Vol 13 (2) ◽  
pp. 389-399 ◽  
Author(s):  
Heather A. Halem ◽  
James A. Cherry ◽  
Michael J. Baum
Keyword(s):  
Female Mice ◽  
Mated Female

A subchronic oral toxicity study on medical herb extract, KIOM CRC#BP10A, in male and female mice

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
ES Cho ◽  
YJ Lee ◽  
JS Park ◽  
J Kim ◽  
NS Kim ◽  
...  
Keyword(s):  
Toxicity Study ◽  
Oral Toxicity ◽  
Male And Female ◽  
Female Mice ◽  
Subchronic Oral Toxicity Study ◽  
Herb Extract
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