Epidermal and splenic antigen-presenting cell function in a retrovirally induced murine immunodeficiency syndrome (MAIDS)

1992 ◽  
Vol 284 (4) ◽  
pp. 189-192 ◽  
Author(s):  
A. Cerny ◽  
S. Izui ◽  
J. -H. Saurat ◽  
F. A. Waldvogel ◽  
H. C. Morse ◽  
...  
Keyword(s):  
Cell Function ◽  
Antigen Presenting Cell ◽  
Immunodeficiency Syndrome ◽  
Antigen Presenting

Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo

10.1038/nm962 ◽  
2003 ◽  
Vol 9 (12) ◽  
pp. 1469-1476 ◽  
Author(s):  
Douglas G Millar ◽  
Kristine M Garza ◽  
Bernhard Odermatt ◽  
Alisha R Elford ◽  
Nobuyuki Ono ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Function ◽  
T Cell Tolerance ◽  
Cell Tolerance ◽  
Antigen Presenting Cell ◽  
Antigen Presenting

scholarly journals Deficiency in NOD Antigen-Presenting Cell Function May Be Responsible for Suboptimal CD4+CD25+ T-Cell-Mediated Regulation and Type 1 Diabetes Development in NOD Mice

Diabetes ◽  
2006 ◽  
Vol 55 (7) ◽  
pp. 2098-2105 ◽  
Author(s):  
P. Alard ◽  
J. N. Manirarora ◽  
S. A. Parnell ◽  
J. L. Hudkins ◽  
S. L. Clark ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
T Cell ◽  
Cell Function ◽  
Nod Mice ◽  
Antigen Presenting Cell ◽  
Diabetes Development ◽  
Antigen Presenting

scholarly journals HLA-DR+ Immature Cells Exhibit Reduced Antigen-Presenting Cell Function But Respond to CD40 Stimulation

Neoplasia ◽  
2005 ◽  
Vol 7 (12) ◽  
pp. 1123-1132 ◽  
Author(s):  
Alberto Pinzon-Charry ◽  
Tammy Maxwell ◽  
Sandro Prato ◽  
Colin Furnival ◽  
Chris Schmidt ◽  
...  
Keyword(s):  
Cell Function ◽  
Antigen Presenting Cell ◽  
Hla Dr ◽  
Cd40 Stimulation ◽  
Antigen Presenting ◽  
Immature Cells

scholarly journals Antigen recognition. V. Requirement for histocompatibility between antigen-presenting cell and B cell in the response to a thymus-dependent antigen, and lack of allogeneic restriction between T and B cells.

1981 ◽  
Vol 154 (3) ◽  
pp. 676-687 ◽  
Author(s):  
E Nisbet-Brown ◽  
B Singh ◽  
E Diener
Keyword(s):  
B Cells ◽  
B Cell ◽  
Cell Function ◽  
Fetal Liver ◽  
T And B Cells ◽  
Antigen Presenting Cell ◽  
Experimental Conditions ◽  
Left Hand ◽  
Antigen Presenting

The restrictions imposed by the major histocompatibility complex on T-B-antigen-presenting cell (APC) interactions were studied with an in vivo adoptive transfer system, using mutually tolerant T and B cells taken from one-way fetal liver chimeras. It was found that the B cells and adoptive recipient (which provides APC function) have to share determinants encoded by the left-hand end of the H-2 complex for cooperation, whereas there is apparently no such requirement for T-B cell syngeneicity. Suppression arising from allogeneic effects between the host and the transferred T or B cells was excluded by the use of tolerant as well as normal adoptive recipients; both were functionally equivalent. We conclude that under experimental conditions, unrestricted helper T cell function and concurrent APC-B cell genetic restriction can be demonstrated in vivo.

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