Dissociation of the effects of training on oxidative metabolism, glucose utilisation and GLUT4 levels in skeletal muscle of streptozotocin-diabetic rats

1994 ◽  
Vol 427 (5-6) ◽  
pp. 444-449 ◽  
Author(s):  
Heikki Kainulainen ◽  
Jyrki Komulainen ◽  
Hans G. Joost ◽  
Veikko Vihko
Keyword(s):  
Skeletal Muscle ◽  
Oxidative Metabolism ◽  
Diabetic Rats ◽  
Glucose Utilisation ◽  
Streptozotocin Diabetic Rats

scholarly journals 3-oxo acid coenzyme A-transferase in normal and diabetic rat muscle

1976 ◽  
Vol 158 (2) ◽  
pp. 509-512 ◽  
Author(s):  
A Fenselau ◽  
K Wallis
Keyword(s):  
Skeletal Muscle ◽  
Coenzyme A ◽  
Substrate Inhibition ◽  
Diabetic Rats ◽  
Diabetic Rat ◽  
Functional Parameters ◽  
Rat Muscle ◽  
Coa Transferase ◽  
Normal Rat ◽  
Streptozotocin Diabetic Rats

The amounts of succinyl-CoA--3-oxo acid CoA-transferase (EC 2.8.3.5) decrease progressively in skeletal muscle in streptozotocin-diabetic rats, reaching after 10 days about 50% of the value in normal rat muscle. Electrofocusing studies indicate the occurrence of partial proteolysis of the enzyme in diabetic muscle. However, several functional parameters relating to acetoacetate utilization, including substrate inhibition, are quite similar for muscle transferase preparations from normal and diseased rats. The development of pathological ketoacidosis is discussed in the light of these observations.

Interorgan metabolism of amino acids in streptozotocin-diabetic ketoacidotic rat

1983 ◽  
Vol 244 (2) ◽  
pp. E151-E158 ◽  
Author(s):  
J. T. Brosnan ◽  
K. C. Man ◽  
D. E. Hall ◽  
S. A. Colbourne ◽  
M. E. Brosnan
Keyword(s):  
Skeletal Muscle ◽  
Amino Acids ◽  
Amino Acid ◽  
Branched Chain Amino Acids ◽  
Diabetic Rats ◽  
Normal Rat ◽  
Diabetic Brain ◽  
Streptozotocin Diabetic Rats ◽  
Branched Chain ◽  
Amino Acid Concentrations

Amino acid concentrations in whole blood, liver, kidney, skeletal muscle, and brain were measured and arteriovenous differences calculated for head, hindlimb, kidney, gut, and liver in control and streptozotocin-diabetic rats. In the control rats, glutamine was released by muscle and utilized by intestine, intestine released citrulline and alanine, liver removed alanine, and the kidneys removed glycine and produced serine. In diabetic rats, the major changes from the pattern of fluxes seen in the normal rat were the release of many amino acids from muscle, with glutamine and alanine predominating, and the uptake of these amino acids by the liver. Glutamine removal by the intestine was suppressed in diabetes, but a large renal uptake of glutamine was evident. Branched-chain amino acids were removed by the diabetic brain, and consequently, brain levels of a number of large neutral amino acids were decreased in diabetes.

793 EFFECT OF TRAINING ON GLUCOSE UPTAKE AND TRANSPORTERS IN SKELETAL MUSCLE OF STREPTOZOTOCIN-DIABETIC RATS

1993 ◽  
Vol 25 (Supplement) ◽  
pp. S142
Author(s):  
J. Komulainen ◽  
V. Vihko ◽  
H. G. Joost ◽  
V. Kovanen ◽  
H. Kainulainen
Keyword(s):  
Skeletal Muscle ◽  
Glucose Uptake ◽  
Diabetic Rats ◽  
Streptozotocin Diabetic Rats

Proximal skeletal muscle alterations in streptozotocin-diabetic rats: A histochemical and morphometric analysis

1991 ◽  
Vol 191 (1) ◽  
pp. 48-56 ◽  
Author(s):  
Maria Medina-Sanchez ◽  
Carmen Rodriguez-Sanchez ◽  
Jose Antonio Vega-Alvarez ◽  
Armando Menendez-Pelaez ◽  
Antonio Perez-Casas
Keyword(s):  
Skeletal Muscle ◽  
Morphometric Analysis ◽  
Diabetic Rats ◽  
Streptozotocin Diabetic Rats

Ultrastructural alterations in skeletal muscle fibers of streptozotocin-diabetic rats

1976 ◽  
Vol 168 (2) ◽  
pp. 239-246 ◽  
Author(s):  
T. T. Chao ◽  
C. D. Ianuzzo ◽  
R. B. Armstrong ◽  
J. T. Albright ◽  
S. E. Anapolle
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibers ◽  
Diabetic Rats ◽  
Ultrastructural Alterations ◽  
Skeletal Muscle Fibers ◽  
Streptozotocin Diabetic Rats
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