Inhibitory effects of sulfonated shale oils (ammonium bituminosulphonates, Ichthyols) on enzymes of polyenoic fatty acid metabolism

1994 ◽  
Vol 286 (3-4) ◽  
pp. 137-141 ◽  
Author(s):  
C. Schewe ◽  
T. Schewe ◽  
E. Rohde ◽  
W. Diezel ◽  
B. M. Czarnetzki
2007 ◽  
Vol 109 (3) ◽  
pp. 471-479 ◽  
Author(s):  
Teresa Puig ◽  
Alejandro Vázquez-Martín ◽  
Joana Relat ◽  
Jordi Pétriz ◽  
Javier A. Menéndez ◽  
...  

2007 ◽  
Vol 5 (4) ◽  
pp. 115
Author(s):  
T. Puig ◽  
J. Relat ◽  
J.A. Menéndez ◽  
R. Porta ◽  
G. Casals ◽  
...  

1990 ◽  
Vol 29 (01) ◽  
pp. 28-34 ◽  
Author(s):  
F. C. Visser ◽  
M. J. van Eenige ◽  
G. Westera ◽  
J. P. Roos ◽  
C. M. B. Duwel

Changes in myocardial metabolism can be detected externally by registration of time-activity curves after administration of radioiodinated fatty acids. In this scintigraphic study the influence of lactate on fatty acid metabolism was investigated in the normal human myocardium, traced with 123l-17-iodoheptadecanoic acid (123l-17-HDA). In patients (paired, n = 7) lactate loading decreased the uptake of 123l-17-HDA significantly from 27 (control: 22-36) to 20 counts/min/pixel (16-31; p <0.05 Wilcoxon). The half-time value increased to more than 60 rriin (n = 5), oxidation decreased from 61 to 42%. Coronary vasodilatation, a well-known side effect of lactate loading, was studied separately in a dipyridamole study (paired, n = 6). Coronary vasodilatation did not influence the parameters of the time-activity curve. These results suggest that changes in plasma lactate level as occurring, among other effects, during exercise will influence the parameters of dynamic 123l-17-HDA scintigraphy of the heart.


Sign in / Sign up

Export Citation Format

Share Document