Risk factors and management of local recurrence following breast conservation surgery

1994 ◽  
Vol 18 (1) ◽  
pp. 76-80 ◽  
Author(s):  
Robert T. Osteen
Keyword(s):  
Risk Factors ◽  
Local Recurrence ◽  
Breast Conservation ◽  
Breast Conservation Surgery ◽  
Conservation Surgery

scholarly journals Evaluation of local recurrence of breast conservation surgery at the Ceará Institute of Cancer

Mastology ◽  
2019 ◽  
Vol 29 (1) ◽  
pp. 10-13
Author(s):  
Giovanni de Freitas Magalhães ◽  
◽  
Francisco Pimentel Cavalcante ◽  
Marcos Venício Alves Lima ◽  
Rafael Bustamante de Castro ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Breast Conservation ◽  
Breast Conservation Surgery ◽  
Conservation Surgery

Clinical significance following breast conservation surgery with or without postoperative irradiation in Japanese women with breast cancer.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e11530-e11530
Author(s):  
Kentaro Tamaki ◽  
Nobumitsu Tamaki ◽  
Yoshihiko Kamada ◽  
Kanou Uehara ◽  
Minoru Miyashita ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Local Recurrence ◽  
Cancer Patients ◽  
Triple Negative ◽  
Breast Conservation ◽  
Surgical Margin ◽  
Breast Conservation Surgery ◽  
Breast Cancer Patients ◽  
Conservation Surgery ◽  
Postoperative Irradiation

e11530 Background: Postoperative irradiation or radiotherapy following breast conservation surgery has been reported to be clinically effective in terms of prevention of local breast cancer recurrences. However, it is also true that its local recurrence rate was only 5% to 10%, suggestive of the lack of its clinical benefits in the great majority of the cases. The purpose of this study was to investigate the significance of post-operative radiotherapy in breast conservation surgery by comparing the groups with or without irradiation. Methods: We retrospectively evaluated 1197 Japanese female breast cancer patients (598 irradiation cases and 599 non-irradiation cases). Radiation was administered in a dose of 50 Gy for all conserved breast and additional 10 Gy in those with positive margins or carcinoma within 5mm from surgical margin. We examined the local recurrence rates in those with or without post-operative irradiation according to the status of surgical margin, ER and HER2 in breast cancer tissues. Results: RFS in the irradiated groups were significantly higher than non-irradiated ones in surgical margin positive (P=0.001, HR: 0.334, 95%CI: 0.14-0.79), negative (P=0.015, 0.362, 95%CI: 0.15-0.82), ER positive (P<0.001, HR: 0.249, 95%CI: 0.11-0.54), HER2 negative (P=0.002, HR: 0.316, 95%CI: 0.15-0.65) and non-triple negative patients (P=0.001, HR: 0.382, 95%CI: 0.21-0.69). However, no significant differences were detected between these two groups in ER negative (P=0.288, HR: 0.586, 95%CI: 0.22-1.57), HER2 positive (P=0.969, HR: 0.971, 95%CI: 0.22-4.24) and triple negative (P=0.336, HR: 0.282, 95%CI: 0.02-3.72) patients. Conclusions: Results of our present study could provide clinically inert information as to the selection of the breast cancer patients following conserve surgery.

The Role of Margin Status and Reexcision in Local Recurrence Following Breast Conservation Surgery

2013 ◽  
Vol 20 (7) ◽  
pp. 2250-2255 ◽  
Author(s):  
Barbara J. Adams ◽  
Christine K. Zoon ◽  
Christina Stevenson ◽  
Padma Chitnavis ◽  
Luke Wolfe ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Breast Conservation ◽  
Margin Status ◽  
Breast Conservation Surgery ◽  
Conservation Surgery
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