CT fogging effect with ischemic cerebral infarcts

1979 ◽  
Vol 18 (4) ◽  
pp. 185-192 ◽  
Author(s):  
H. Becker ◽  
H. Desch ◽  
H. Hacker ◽  
A. Pencz
1981 ◽  
Vol 22 (2) ◽  
pp. 61-65 ◽  
Author(s):  
Elisabeth Bech Skriver ◽  
T. Skyh�j Olsen

1996 ◽  
Vol 243 (7) ◽  
pp. 511-515 ◽  
Author(s):  
R. A. H. Hoekstra-van Dalen ◽  
J. P. M. Cillessen ◽  
L. J. Kappelle ◽  
J. Gijn

Stroke ◽  
2009 ◽  
Vol 40 (3) ◽  
pp. 677-682 ◽  
Author(s):  
Jane S. Saczynski ◽  
Sigurdur Sigurdsson ◽  
Maria K. Jonsdottir ◽  
Gudny Eiriksdottir ◽  
Palmi V. Jonsson ◽  
...  

2014 ◽  
Vol 17 (5) ◽  
pp. 374-381 ◽  
Author(s):  
Terakeith Lertsburapa ◽  
Diana Vargas ◽  
Geralyn Lambert-Messerlian ◽  
Umadevi Tantravahi ◽  
Füsun Gündoğan ◽  
...  

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Lauren Koffman ◽  
Gabor Toth ◽  
M. Shazam Hussain ◽  
Magdy Selim ◽  
Peter Rasmussen ◽  
...  

Introduction: Iron-dependent formation of reactive oxygen species has been implicated in the development of vasospasm (VSP) and neuronal injury following experimental subarachnoid hemorrhage (SAH). We report the association between unbound (“free”) iron in CSF of SAH patients and the risk of angiographic vasospasm and cerebral infarcts (CI) on neuroimaging from a recently completed pilot study. Methods: Samples of cerebrospinal fluid (CSF) were obtained on days 1, 3, and 5. A fluorometric assay that relies on an oxidation sensitive probe was used to measure redox active iron (REDOX-Fe). Ceruloplasmin (Cp) concentration and levels of malondialdehyde (MDA), a marker of lipid peroxidation were also measured. We prospectively collected and recorded demographic, clinical, and radiological data. Logistic regression and Wilcoxon Rank Sum test were used. Results: Five of 12 patients developed angiographic VSP (41.6%) and eight developed CI (66.6%). Mean REDOX-Fe was higher in patients with CI (3.96 ± 0.97 Vs. 2.77 ± 0.87 mcg/dl, p 0.07), particularly in patients with deep-seated strokes (4.56 ± 0.67 Vs. 3.35 ± 0.89, p 0.03). Levels of Cp at day 3 were lower in patients with deep strokes (34,092 ± 23,780 Vs. 86,045 ± 34,752 ng/ml, p 0.03). A trend towards higher REDOX-Fe on day 3 in patients who developed VSP (4.52 ± 1.16 Vs. 2.96 ± 0.71, p 0.07), and lower Cp levels on day 5 (45,033 ± 29,079 Vs. 63,044 ± 24,821, p 0.1) was found. Levels of MDA were higher in patients who developed CI (10.36 ± 4.36 Vs. 5.9 ± 4.2 nmol, p 0.08). Conclusions: In this preliminary study we found higher concentrations of redox active iron in CSF of SAH patients who develop deep-seated CI on neuroimaging. Evidence of increased oxidative damage correlated with development of CI. A possible association between non-protein bound iron and angiographic VSP is suggested as well. Ceruloplasmin may exert a protective effect in this setting. Further studies are needed to validate these findings.


PEDIATRICS ◽  
1987 ◽  
Vol 79 (6) ◽  
pp. 1024-1026
Author(s):  
LUIS A. ALVAREZ ◽  
SHLOMO SHINNAR ◽  
SOLOMON L. MOSHÉ

Infantile spasms are an age-specific seizure disorder that occur in infants with no known underlying disorder or prior neurologic insult (cryptogenic group) as well as in infants with a variety of genetic disorders or known prior neurologic insult (symptomatic group).1-8 The presence of infantile spasms is associated with a high incidence of developmental retardation (87%)3 even in previously normal infants.3,5-7 Although there are many contradictory studies, it is generally believed that the infants in the symptomatic group, especially those with abnormal findings on neurologic examination prior to the onset of the seizures, have a significantly higher incidence of mental retardation and epilepsy than the infants in the cryptogenic group.1-9


2017 ◽  
Vol 65 (1) ◽  
pp. e26767 ◽  
Author(s):  
Foluso J. Ogunsile ◽  
Kelli L. Currie ◽  
Mark Rodeghier ◽  
Adetola Kassim ◽  
Michael R. DeBaun ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document