Segregation distorter in D. melanogaster males: An effect of female genotype on recovery

1969 ◽  
Vol 105 (3) ◽  
pp. 262-274 ◽  
Author(s):  
R. E. Denell ◽  
B. H. Judd
Keyword(s):  
Segregation Distorter ◽  
Female Genotype

scholarly journals Traits that influence longevity in mice: a second look.

Genetics ◽  
1992 ◽  
Vol 132 (1) ◽  
pp. 229-239
Author(s):  
K B Dear ◽  
M Salazar ◽  
A L Watson ◽  
R S Gelman ◽  
R Bronson ◽  
...  
Keyword(s):  
Life Span ◽  
Genetic Factors ◽  
Viral Infections ◽  
Genetic Interactions ◽  
Chromosome 9 ◽  
Chromosome 4 ◽  
Histological Findings ◽  
Male And Female ◽  
Female Genotype ◽  
Dominant Black

Abstract Analysis of genetic interactions in the F2 of an intercross of (C57BL/6 x DBA/2) F1J revealed influences of genetic factors on life span. Females lived longer than males. Dilute brown females died sooner than females of other colors. H-2b/H-2b males died sooner than H-2b/H-2d or H-2d/H-2d males, except that among dilute brown males those of typeH-2b/H-2d died sooner. Cluster analysis suggested that male and female genotypes each fall into two groups, with female dilute brown mice having shorter lives than other females, and male H-2b/H-2b mice except dilute brown and dilute brown H-2b/H-2d mice having shorter lives than other males. The association of heterozygosity with life span was clearer in females than in males, yet the longest-lived female genotype was homozygous H-2d/H-2d, of dominant Black phenotype at the Brown locus of chromosome 4, and homozygous dd at the Dilute locus of chromosome 9. The shortest-lived females were dilute brown H-2b/H-2b. The longest-lived and shortest-lived male genotypes were dilute brown H-2d/H-2d and dilute brown H-2b/H-2d, respectively. Although histological findings at postmortem differed between the sexes, there was no association of particular disorders with other genetic markers. The importance of H-2 in males was confirmed, but the allelic effects were perturbed, possibly by the absence of Sendai infection in this experiment. Overall our studies suggest that genetic influences on life span involve interactions between loci, and allelic interactions may change with viral infections or other environmental factors.

scholarly journals Female genotype affects male success in sperm competition

1997 ◽  
Vol 264 (1387) ◽  
pp. 1491-1495 ◽  
Author(s):  
Nina Wilson ◽  
Simon C. Tubman ◽  
Paul E. Eady ◽  
Gordon W. Robertson
Keyword(s):  
Sperm Competition ◽  
Female Genotype

scholarly journals Evidence for Two Regions in the Mouse t Complex Controlling Transmission Ratios

1981 ◽  
Vol 38 (3) ◽  
pp. 315-325 ◽  
Author(s):  
Józefa Styrna ◽  
Jan Klein
Keyword(s):  
Lethal Factor ◽  
Compound Heterozygote ◽  
The Other ◽  
Transmission Ratio ◽  
Crossing Over ◽  
Normal Length ◽  
T Complex ◽  
Segregation Distorter ◽  
Haplotype A ◽  
Made In

SUMMARYFour new t haplotypes, tTu1 through tTu4, are described, three of them derived from the tw12tf haplotype and one (tTu4) from the tw2 haplotype. The tTu1 and tTu4 haplotypes cause taillessness in T/tTu1 or T/tTu4 heterozygotes, lack the lethality factor, weakly suppress recombination in the T−H−2 interval, and are transmitted to offspring from tTu/ + males at nearly Mendelian ratios. The tTu3 haplotype resembles tTu1 and tTu4 except for the fact that the T/tTu3 heterozygotes have normal-length tails. The tTu2 haplotype probably carries the lethal factor of tTu12tf, suppresses crossing-over in the T-H-2 and tf-H-2 intervals, and displays a slightly subnormal transmission ratio. In the compound heterozygote tTu1/tTu2, the male transmission ratio of the tTu1 chromosome is close to that of the original tTu12tf haplotype. A similar effect is observed in the tTu3/tTu2 heterozygote. This observation is interpreted as evidence for two regions within the t complex controlling the male transmission ratios. One of the regions is close to the tail-modifying region, the other is close to the lethality factor. Our findings parallel closely those made in the segregation distorter system in Drosophila.

scholarly journals Does segregating variation in sexual or microhabitat preferences lead to non-random mating within a population of Drosophila melanogaster ?

2009 ◽  
Vol 6 (1) ◽  
pp. 102-105 ◽  
Author(s):  
Brad R. Foley ◽  
Anne Genissel ◽  
Harmon L. Kristy ◽  
Sergey V. Nuzhdin
Keyword(s):  
Recombinant Inbred Lines ◽  
Random Mating ◽  
Population Level ◽  
Inbred Lines ◽  
Male Mating ◽  
Complex Environment ◽  
Level Variation ◽  
Group Preference ◽  
Female Genotype ◽  
Microhabitat Preferences

Variation in female choice for mates has implications for the maintenance of genetic variation and the evolution of male traits. Yet, estimates of population-level variation in male mating success owing to female genotype are rare. Here, we used a panel of recombinant inbred lines to estimate the strength of selection at many genetic loci in a single generation and attempt to assess differences between females with respect to the males they mated with. We performed selection assays in a complex environment to allow differences in habitat or social group preference to be expressed. We detected directional selection at loci across the genome, but are unable to provide support for differential male success because of variation in female genotype.

scholarly journals MULTIPLE MEIOTIC DRIVE SYSTEMS IN THE DROSOPHILA MELANOGASTER MALE

Genetics ◽  
1972 ◽  
Vol 72 (1) ◽  
pp. 105-115
Author(s):  
George L Gabor Miklos ◽  
Armon F Yanders ◽  
W J Peacock
Keyword(s):  
Drosophila Melanogaster ◽  
Survival Probability ◽  
Sex Chromosome ◽  
Meiotic Drive ◽  
The Other ◽  
Segregation Distorter ◽  
Two Systems ◽  
Combined Action ◽  
Drive Systems

ABSTRACT The behaviour of two "meiotic drive" systems, Segregation-Distorter (SD) and the sex chromosome sc4sc8 has been examined in the same meiocyte. It has been found that the two systems interact in a specific way. When the distorting effects of SD and sc4sc8 are against each other, there is no detectable interaction. Each system is apparently oblivious to the presence of the other, gametes being produced according to independence expectations. However when the affected chromosomes are at the same meiotic pole an interaction occurs; the survival probability of the gamete containing both distorted chromosomal products is increased, rather than being decreased by the combined action of two systems.

scholarly journals Assessing the acoustic behaviour of Anopheles gambiae (s.l.) dsxF mutants: implications for vector control

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Matthew P. Su ◽  
Marcos Georgiades ◽  
Judit Bagi ◽  
Kyros Kyrou ◽  
Andrea Crisanti ◽  
...  
Keyword(s):  
Anopheles Gambiae ◽  
Population Control ◽  
Beat Frequency ◽  
Phenotypic Traits ◽  
Gene Drive ◽  
Anopheles Gambiae S.L ◽  
Female Genotype ◽  
Female Specific ◽  
The Impact ◽  
Dose Dependent

Abstract Background Release of gene-drive mutants to suppress Anopheles mosquito reproduction is a promising method of malaria control. However, many scientific, regulatory and ethical questions remain before transgenic mosquitoes can be utilised in the field. At a behavioural level, gene-drive carrying mutants should be at least as sexually attractive as the wildtype populations they compete against, with a key element of Anopheles copulation being acoustic courtship. We analysed sound emissions and acoustic preference in a doublesex mutant previously used to collapse Anopheles gambiae (s.l.) cages. Methods Anopheles rely on flight tones produced by the beating of their wings for acoustic mating communication. We assessed the impact of disrupting a female-specific isoform of the doublesex gene (dsxF) on the wing beat frequency (WBF; measured as flight tone) of males (XY) and females (XX) in homozygous dsxF− mutants (dsxF−/−), heterozygous dsxF− carriers (dsxF+/−) and G3 dsxF+ controls (dsxF+/+). To exclude non-genetic influences, we controlled for temperature and wing length. We used a phonotaxis assay to test the acoustic preferences of mutant and control mosquitoes. Results A previous study showed an altered phenotype only for dsxF−/− females, who appear intersex, suggesting that the female-specific dsxF allele is haplosufficient. We identified significant, dose-dependent increases in the WBF of both dsxF−/− and dsxF+/− females compared to dsxF+/+ females. All female WBFs remained significantly lower than male equivalents, though. Males showed stronger phonotactic responses to the WBFs of control dsxF+/+ females than to those of dsxF+/− and dsxF−/− females. We found no evidence of phonotaxis in any female genotype. No male genotypes displayed any deviations from controls. Conclusions A prerequisite for anopheline copulation is the phonotactic attraction of males towards female flight tones within mating swarms. Reductions in mutant acoustic attractiveness diminish their mating efficiency and thus the efficacy of population control efforts. Caged population assessments may not successfully reproduce natural mating scenarios. We propose to amend existing testing protocols to better reflect competition between mutants and target populations. Our findings confirm that dsxF disruption has no effect on males; for some phenotypic traits, such as female WBFs, the effects of dsxF appear dose-dependent rather than haplosufficient.

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