Influence of exogenous porcine growth hormone on vitamin D metabolism and calcium and phosphorus absorption in intact pigs

1994 ◽  
Vol 54 (6) ◽  
pp. 489-492 ◽  
Author(s):  
I. Denis ◽  
M. Thomasset ◽  
A. Pointillart
1985 ◽  
Vol 68 (1) ◽  
pp. 97-100 ◽  
Author(s):  
U. Gafter ◽  
S. Edelstein ◽  
J. Levi

1. The effect of bicarbonate (NaHCO3) feeding on intestinal absorption of calcium and phosphorus and vitamin D metabolism was investigated. Gut sac uptake of 45Ca and [32P]phosphate in vitro, as well as the plasma level of vitamin D metabolites, was determined in rats fed with NaHCO3 for 9 days and their pair-fed controls. 2. Duodenal uptake of 45Ca and [32P]phosphate by alkalotic rats was less than duodenal uptake by controls. 1,25(OH)2D plasma level was much higher in alkalotic rats than in their controls, and 25(OH)D slightly higher than in controls. 3. These data suggest that NaHCO3 feeding causes a substantial increase in 1,25(OH)2D plasma level, but interferes with calcium and phosphorus absorption in the duodenum.


Endocrinology ◽  
1981 ◽  
Vol 108 (3) ◽  
pp. 1064-1070 ◽  
Author(s):  
E. MARTIN SPENCER ◽  
OTTE TOBIASSEN

1996 ◽  
Vol 211 (3) ◽  
pp. 281-286 ◽  
Author(s):  
H. P. Schedl ◽  
T. Conway ◽  
R. L. Horst ◽  
D. L. Miller ◽  
C. K. Brown

Author(s):  
Maria Klatka ◽  
Małgorzata Partyka ◽  
Agnieszka Polak ◽  
Barbara Terpiłowska ◽  
Michał Terpiłowski ◽  
...  

1980 ◽  
Vol 239 (6) ◽  
pp. G480-G484 ◽  
Author(s):  
U. Gafter ◽  
J. A. Kraut ◽  
D. B. Lee ◽  
V. Silis ◽  
M. W. Walling ◽  
...  

To investigate the effect of metabolic acidosis on intestinal calcium (Ca) and phosphorus (P) absorption and vitamin D metabolism, metabolic balance studies and in vitro gut sac uptake of 45Ca and [32P]phosphate were performed in rats maintained on low-Ca and moderately low-P diet and fed NH4Cl for 3 or 9 days and pair-fed controls. Plasma 1,25(OH)2D concentration was measured in the rats fed NH4Cl for 9 days and their controls. Net Ca and P absorption was 87–92% in the acidotic rats and did not differ from control. Moreover, gut sac uptakes of 45Ca and [32P]phosphate were not different from control. Plasma 1,25(OH)2D was higher in the ammonium chloride-fed rats than in controls (213 +/- 44 vs. 110 +/- 12 pg/ml), and serum P was lower in the acidotic animals (4.6 +/- 0.7 vs. 7.6 +/- 0.3 mg/dl). These data indicate that metabolic acidosis does not depress the augmented intestinal absorption of calcium and phosphorus noted during their dietary deprivation nor reduce the plasma level of 1,25(OH)2D.


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