Ribosomal gene amplification in multinucleate oocytes of the egg brooding hylid frog Flectonotus pygmaeus

Chromosoma ◽  
1982 ◽  
Vol 85 (4) ◽  
pp. 475-488 ◽  
Author(s):  
H. C. Macgregor ◽  
Eugenia M. del Pino
Keyword(s):  
Gene Amplification ◽  
Ribosomal Gene ◽  
Egg Brooding

A comparison of ribosomal gene amplification in uni- and multinucleolate oocytes

1969 ◽  
Vol 57 (2-3) ◽  
pp. 240-250 ◽  
Author(s):  
W VINCENT ◽  
H HALVORSON ◽  
H CHEN ◽  
D SHIN
Keyword(s):  
Gene Amplification ◽  
Ribosomal Gene

Ribosomal gene amplification in oocytes of the lizardPodarcis sicula

1991 ◽  
Vol 29 (2) ◽  
pp. 95-102 ◽  
Author(s):  
Chiara M. Motta ◽  
Piero Andreuccetti ◽  
Silvana Filosa
Keyword(s):  
Gene Amplification ◽  
Ribosomal Gene

A role for upstream binding factor in organizing ribosomal gene chromatin

2006 ◽  
Vol 73 ◽  
pp. 77-84 ◽  
Author(s):  
Jane E. Wright ◽  
Christine Mais ◽  
José-Luis Prieto ◽  
Brian McStay
Keyword(s):  
Nucleolar Organizer ◽  
Ribosomal Gene ◽  
Rna Polymerase I ◽  
Nucleolar Organizer Regions ◽  
Binding Factor ◽  
Upstream Binding Factor ◽  
Acrocentric Chromosomes ◽  
Polymerase I ◽  
Secondary Constrictions ◽  
Active Nors

Human ribosomal genes are located in NORs (nucleolar organizer regions) on the short arms of acrocentric chromosomes. During metaphase, previously active NORs appear as prominent chromosomal features termed secondary constrictions, which are achromatic in chromosome banding and positive in silver staining. The architectural RNA polymerase I transcription factor UBF (upstream binding factor) binds extensively across the ribosomal gene repeat throughout the cell cycle. Evidence that UBF underpins NOR structure is provided by an examination of cell lines in which large arrays of a heterologous UBF binding sequences are integrated at ectopic sites on human chromosomes. These arrays efficiently recruit UBF even to sites outside the nucleolus, and during metaphase form novel silver-stainable secondary constrictions, termed pseudo-NORs, that are morphologically similar to NORs.

Reevaluation of gene amplification in medulloblastomas

2004 ◽  
Vol 216 (03) ◽  
Author(s):  
T Lenschen ◽  
J Mühlisch ◽  
H Jürgens ◽  
C Plass ◽  
D Smiraglia ◽  
...  
Keyword(s):  
Gene Amplification

HER-2 gene amplification in pancreatic cancer

2004 ◽  
Vol 42 (05) ◽  
Author(s):  
K Borka ◽  
A Kiss ◽  
A Tőkés ◽  
P Kaliszky ◽  
P Kupcsulik ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Gene Amplification ◽  
Her 2
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