BCR (non-certified) reference materials for dioxins and furans in milk powder

1995 ◽  
Vol 352 (1-2) ◽  
pp. 179-183 ◽  
Author(s):  
E. A. Maier ◽  
R. Van Cleuvenbergen ◽  
G. N. Kramer ◽  
L. G. M.Th. Tuinstra ◽  
J. Pauwels
Keyword(s):  
Reference Materials ◽  
Certified Reference Materials ◽  
Milk Powder ◽  
Dioxins And Furans

Application of microbiological (certified) reference materials

1997 ◽  
Vol 35 (11-12) ◽  
pp. 467-470 ◽  
Author(s):  
K. A. Mooijman ◽  
A. H. Havelaar
Keyword(s):  
Reference Materials ◽  
Certified Reference Materials ◽  
Milk Powder ◽  
Optimal Number ◽  
Power Calculation ◽  
Calculation Technique ◽  
Certified Value ◽  
Degree Of Control ◽  
The Difference ◽  
The Given

The development of microbiological reference materials (RMs) has succesfully led to the certification of six materials (CRMs) and to the production of a wider range of non-certified reference materials. Both materials (RM and CRM) are prepared in the same way. They consist of gelatin capsules filled with milk powder artificially contaminated with a selected test strain. The difference between an RM and a CRM is the degree of control of the materials. Because of this difference the RMs and CRMs differ largely in price and application. An RM is intended to be used in daily quality control (QC) of microbiological (routine) analysis. For this purpose the use of a control chart can be very useful. A CRM is intended to be used incidentally, e.g. for validation of a (new) method, or for a complete check of the performance of the laboratory and technicians. The certified value of a microbiological CRM is method dependent. A user of a CRM will compare their mean results with the given certified value and confidence limits. With a so-called power calculation technique the optimal number of capsules and replicates for a CRM were calculated.

Preparation of certified reference materials of traces of chromium and arsenic in high purity water and infant milk powder

1993 ◽  
Vol 345 (2-4) ◽  
pp. 278-281 ◽  
Author(s):  
P. K. Gupta ◽  
Chetna Kaw ◽  
Sunita Ganju ◽  
A. K. Agrawal ◽  
R. Ramchandran ◽  
...  
Keyword(s):  
Reference Materials ◽  
High Purity ◽  
Certified Reference Materials ◽  
Milk Powder ◽  
Infant Milk Powder

Development of reference materials with the composition of propyl and isopropyl alcohol solutions

2020 ◽  
pp. 66-72
Author(s):  
Irina A. Piterskikh ◽  
Svetlana V. Vikhrova ◽  
Nina G. Kovaleva ◽  
Tatyana O. Barynskaya
Keyword(s):  
Reference Materials ◽  
Measurement Errors ◽  
Isopropyl Alcohol ◽  
Certified Reference Materials ◽  
Toxic Substances ◽  
Biological Objects ◽  
Margin Of Error ◽  
Measurement Results ◽  
And Control ◽  
Characteristic Mass

Certified reference materials (CRM) composed of propyl (11383-2019) and isopropyl (11384-2019) alcohols solutions were created for validation of measurement procedures and control of measurement errors of measurement results of mass concentrations of toxic substances (alcohol) in biological objects (urine, blood) and water. Two ways of establishing the value of the certified characteristic – mass consentration of propanol-1 or propanol-2 have been studied. The results obtained by the preparation procedure and comparison with the standard are the same within the margin of error.

PROGRESS ON THE DEVELOPMENT OF CERTIFIED REFERENCE MATERIALS FOR Aβ1-42

2017 ◽  
Vol 13 (7) ◽  
pp. P1512
Author(s):  
Sébastien Boulo ◽  
Julia Kuhlmann ◽  
Andreas Leinenbach ◽  
Tobias Bittner ◽  
Leentje Demeyer ◽  
...  
Keyword(s):  
Reference Materials ◽  
Certified Reference Materials

scholarly journals Development and certification of a reference material for zearalenone in maize germ oil

2021 ◽  
Author(s):  
Juliane Riedel ◽  
Sebastian Recknagel ◽  
Diana Sassenroth ◽  
Tatjana Mauch ◽  
Sabine Buttler ◽  
...  
Keyword(s):  
Reference Material ◽  
Reference Materials ◽  
Mass Fraction ◽  
High Performance ◽  
Certified Reference Materials ◽  
Maximum Level ◽  
Whole Process ◽  
Commission Regulation ◽  
Maize Oil ◽  
Maize Germ

AbstractZearalenone (ZEN), an estrogenic mycotoxin produced by several species of Fusarium fungi, is a common contaminant of cereal-based food worldwide. Due to frequent occurrences associated with high levels of ZEN, maize oil is a particular source of exposure. Although a European maximum level for ZEN in maize oil exists according to Commission Regulation (EC) No. 1126/2007 along with a newly developed international standard method for analysis, certified reference materials (CRM) are still not available. To overcome this lack, the first CRM for the determination of ZEN in contaminated maize germ oil (ERM®-BC715) was developed in the frame of a European Reference Materials (ERM®) project according to the requirements of ISO Guide 35. The whole process of CRM development including preparation, homogeneity and stability studies, and value assignment is presented. The assignment of the certified mass fraction was based upon an in-house study using high-performance liquid chromatography isotope dilution tandem mass spectrometry. Simultaneously, to support the in-house certification study, an interlaboratory comparison study was conducted with 13 expert laboratories using different analytical methods. The certified mass fraction and expanded uncertainty (k = 2) of ERM®-BC715 (362 ± 22) μg kg−1 ZEN are traceable to the SI. This reference material is intended for analytical quality control and contributes to the improvement of consumer protection and food safety. Graphical abstract

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