Atomic Force Microscopy of technological and biological samples

1993 ◽  
Vol 346 (1-3) ◽  
pp. 58-60
Author(s):  
Gernot Friedbacher ◽  
Manfred Grasserbauer
Keyword(s):  
Atomic Force Microscopy ◽  
Biological Samples ◽  
Force Microscopy ◽  
Atomic Force

Quantitative mechanical analysis of indentations on layered, soft elastic materials

Soft Matter ◽  
2019 ◽  
Vol 15 (8) ◽  
pp. 1776-1784 ◽  
Author(s):  
Bryant L. Doss ◽  
Kiarash Rahmani Eliato ◽  
Keng-hui Lin ◽  
Robert Ros
Keyword(s):  
Atomic Force Microscopy ◽  
Elastic Modulus ◽  
Cell Mechanics ◽  
Biological Samples ◽  
Mechanical Analysis ◽  
Elastic Materials ◽  
Mechanical Heterogeneity ◽  
Popular Method ◽  
Force Microscopy ◽  
Atomic Force

Atomic force microscopy (AFM) is becoming an increasingly popular method for studying cell mechanics, however the existing analysis tools for determining the elastic modulus from indentation experiments are unable to quantitatively account for mechanical heterogeneity commonly found in biological samples.

Label-free quantification of activated NF-κB in biological samples by atomic force microscopy

2010 ◽  
Vol 25 (11) ◽  
pp. 2490-2496 ◽  
Author(s):  
Michele Menotta ◽  
Rita Crinelli ◽  
Elisa Carloni ◽  
Marzia Bianchi ◽  
Elisa Giacomini ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Biological Samples ◽  
Label Free ◽  
Force Microscopy ◽  
Label Free Quantification ◽  
Atomic Force ◽  
Free Quantification

Robust classification of biological samples in atomic force microscopy images via multiple filtering cooperation

2017 ◽  
Vol 133 ◽  
pp. 221-233 ◽  
Author(s):  
Paola Casti ◽  
Arianna Mencattini ◽  
Innocenzo Sammarco ◽  
Sowmya Jayaraman Velappa ◽  
Gabriele Magna ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Biological Samples ◽  
Robust Classification ◽  
Force Microscopy ◽  
Atomic Force ◽  
Microscopy Images

Toward the realization of reproducible Atomic Force Microscopy measurements of elastic modulus in biological samples

2015 ◽  
Vol 48 (6) ◽  
pp. 1099-1104 ◽  
Author(s):  
A. Demichelis ◽  
C. Divieto ◽  
L. Mortati ◽  
S. Pavarelli ◽  
G. Sassi ◽  
...  
Keyword(s):  
Atomic Force Microscopy ◽  
Elastic Modulus ◽  
Biological Samples ◽  
Force Microscopy ◽  
Atomic Force

scholarly journals Practical applications of atomic force microscopy in biomedicine

STEMedicine ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. e15
Author(s):  
Nicola Galvanetto
Keyword(s):  
Atomic Force Microscopy ◽  
Drug Discovery ◽  
Membrane Proteins ◽  
Biological Samples ◽  
Live Imaging ◽  
Proof Of Concept ◽  
Living Matter ◽  
Practical Applications ◽  
Force Microscopy ◽  
Atomic Force

The last thirty years of progress of atomic force microscopy (AFM) applied to living matter is reviewed with a focus on potential uses in drug discovery or screening of patient samples. AFM-based technologies are still at Proof of Concept level - or below, however, they are particularly promising for i) live imaging of unlabeled membrane proteins and ii) nanomechanical screening of biological samples, e.g. cancer biopsies.

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