Modulation of EL-4 mouse lymphoma cell proliferation by macrophages and tumor related factors

1984 ◽  
Vol 49 (1) ◽  
pp. 45-51 ◽  
Author(s):  
Augusto Pessina ◽  
Paolo Brambilla ◽  
Paolo Mocarelli
Keyword(s):  
Cell Proliferation ◽  
Lymphoma Cell ◽  
Related Factors ◽  
Mouse Lymphoma

Complementary inhibition of synoviocyte, smooth muscle cell or mouse lymphoma cell proliferation by a vanadyl curcumin complex compared to curcumin alone

2004 ◽  
Vol 98 (12) ◽  
pp. 2063-2070 ◽  
Author(s):  
Katherine H. Thompson ◽  
Karin Böhmerle ◽  
Elena Polishchuk ◽  
Candice Martins ◽  
Philip Toleikis ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Lymphoma Cell ◽  
Mouse Lymphoma

Isolation and Characterization of Apoptosis-Resistant Mutants from a Radiosensitive Mouse Lymphoma Cell Line

1998 ◽  
Vol 149 (1) ◽  
pp. 41 ◽  
Author(s):  
Hidehiko Kawai ◽  
Yukika Kitamura ◽  
Osamu Nikaido ◽  
Masaaki Tatsuka ◽  
Hiroko Hama-Inaba ◽  
...  
Keyword(s):  
Cell Line ◽  
Lymphoma Cell ◽  
Lymphoma Cell Line ◽  
Isolation And Characterization ◽  
Resistant Mutants ◽  
Mouse Lymphoma

scholarly journals MicroRNA-146a-5p enhances radiosensitivity in hepatocellular carcinoma through replication protein A3-induced activation of the DNA repair pathway

2019 ◽  
Vol 316 (3) ◽  
pp. C299-C311 ◽  
Author(s):  
Jing Luo ◽  
Zhong-Zhou Si ◽  
Ting Li ◽  
Jie-Qun Li ◽  
Zhong-Qiang Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Proliferation ◽  
Dna Damage ◽  
Dna Repair ◽  
Dna Damage Repair ◽  
Replication Protein ◽  
Repair Pathway ◽  
Related Factors ◽  
Damage Repair ◽  
Hcc Cells

Hepatocellular carcinoma (HCC) is known for its high mortality rate worldwide. Based on intensive studies, microRNA (miRNA) expression functions in tumor suppression. Therefore, we aimed to evaluate the contribution of miR-146a-5p to radiosensitivity in HCC through the activation of the DNA damage repair pathway by binding to replication protein A3 (RPA3). First, the limma package of R was performed to differentially analyze HCC expression chip, and regulative miRNA of RPA3 was predicted. Expression of miR-146a-5p, RPA3, and DNA damage repair pathway-related factors in tissues and cells was determined. The effects of radiotherapy on the expression of miR-146a-5p and RPA3 as well as on cell radiosensitivity, proliferation, cell cycle, and apoptosis were also assessed. The results showed that there exists a close correlation between miR-146a and the radiotherapy effect on HCC progression through regulation of RPA3 and the DNA repair pathway. The positive rate of ATM, pCHK2, and Rad51 in HCC tissues was higher when compared with that of the paracancerous tissues. SMMC-7721 and HepG2 cell proliferation were significantly inhibited following 8 Gy 6Mv dose. MiR-146a-5p restrained the expression of RPA3 and promoted the expression of relative genes associated with the DNA repair pathway. In addition, miR-146a-5p overexpression suppresses cell proliferation and enhances radiosensitivity and cell apoptosis in HCC cells. In conclusion, the present study revealed that miR-146a-5p could lead to the restriction of proliferation and the promotion of radiosensitivity and apoptosis in HCC cells through activation of DNA repair pathway and inhibition of RPA3.

cCMP causes caspase-dependent apoptosis in mouse lymphoma cell lines

2015 ◽  
Vol 98 (1) ◽  
pp. 119-131 ◽  
Author(s):  
Sabine Wolter ◽  
Christina Kloth ◽  
Marina Golombek ◽  
Fanni Dittmar ◽  
Lisa Försterling ◽  
...  
Keyword(s):  
Cell Lines ◽  
Lymphoma Cell ◽  
Mouse Lymphoma

Evaluation of the l5178y mouse lymphoma cell mutagenesis assay: Quality-control guidelines and response categories

1988 ◽  
Vol 12 (S13) ◽  
pp. 19-36 ◽  
Author(s):  
William J. Caspary ◽  
Y. Jack Lee ◽  
Scott Poulton ◽  
Brian C. Myhr ◽  
Ann D. Mitchell ◽  
...  
Keyword(s):  
Quality Control ◽  
Lymphoma Cell ◽  
Mouse Lymphoma

Dehydroepiandrosterone-Dexamethasone Interactions on Nb2 Lymphoma Cell Proliferation

2011 ◽  
Author(s):  
Yanal Shafagoj ◽  
Raphael Witorsch ◽  
Milton Sholley ◽  
William Regelson ◽  
Mohammed Kalimi
Keyword(s):  
Cell Proliferation ◽  
Lymphoma Cell

scholarly journals Phytochemical profile and antioxidation activity of annona fruit and its effect on lymphoma cell proliferation

2019 ◽  
Vol 8 (1) ◽  
pp. 58-68
Author(s):  
Huda Mohammed Al‐Shaya ◽  
Haiwen Li ◽  
Obaid U. Beg ◽  
Anwar A. Hamama ◽  
Sarah Melissa Witiak ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Lymphoma Cell ◽  
Antioxidation Activity ◽  
Phytochemical Profile
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