The perineuronal net in the fastigial nucleus of the rat cerebellum

1984 ◽  
Vol 170 (1) ◽  
pp. 79-85 ◽  
Author(s):  
M. Lafarga ◽  
M. T. Berciano ◽  
M. Blanco
Keyword(s):  
Fastigial Nucleus ◽  
Perineuronal Net ◽  
Rat Cerebellum

Background impulse activity of neurons of the fastigial nucleus in the rat cerebellum

1992 ◽  
Vol 23 (4) ◽  
pp. 323-330
Author(s):  
A. S. Amatuni ◽  
R.Sh Sarkisyan ◽  
E. A. Korkotyan ◽  
A. K. Melikyan
Keyword(s):  
Impulse Activity ◽  
Fastigial Nucleus ◽  
Background Impulse Activity ◽  
Rat Cerebellum

scholarly journals Acrylamide Does Not Cause Apparent Changes in Genetic Expression of Creatine Kinase in Rat Cerebellum

2004 ◽  
Vol 26 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Bambang WISPRIYONO ◽  
Masato MATSUOKA ◽  
Hideki IGISU
Keyword(s):  
Creatine Kinase ◽  
Genetic Expression ◽  
Rat Cerebellum

scholarly journals Comprehensive phenotyping revealed transient startle response reduction and histopathological gadolinium localization to perineuronal nets after gadodiamide administration in rats

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Johanna Habermeyer ◽  
Janina Boyken ◽  
Julia Harrer ◽  
Fabio Canneva ◽  
Veronika Ratz ◽  
...  
Keyword(s):  
Neuronal Cell ◽  
Cell Loss ◽  
Repeated Administration ◽  
Perineuronal Net ◽  
Treatment Groups ◽  
Long Time ◽  
Clinical Consequences ◽  
Molecular Weight Fractions ◽  
Clinical Mri ◽  
Pathway Deregulation

AbstractGadolinium based contrast agents (GBCAs) are widely used in clinical MRI since the mid-1980s. Recently, concerns have been raised that trace amounts of Gadolinium (Gd), detected in brains even long time after GBCA application, may cause yet unrecognized clinical consequences. We therefore assessed the behavioral phenotype, neuro-histopathology, and Gd localization after repeated administration of linear (gadodiamide) or macrocyclic (gadobutrol) GBCA in rats. While most behavioral tests revealed no difference between treatment groups, we observed a transient and reversible decrease of the startle reflex after gadodiamide application. Residual Gd in the lateral cerebellar nucleus was neither associated with a general gene expression pathway deregulation nor with neuronal cell loss, but in gadodiamide-treated rats Gd was associated with the perineuronal net protein aggrecan and segregated to high molecular weight fractions. Our behavioral finding together with Gd distribution and speciation support a substance class difference for Gd presence in the brain after GBCA application.

Impacts of Egyptian propolis extract on rat cerebellum intoxicated by aluminum silicate: histopathological studies

2019 ◽  
Vol 26 (21) ◽  
pp. 22061-22068
Author(s):  
Nahed A. Omar ◽  
Ali H. Abu-Almaaty ◽  
Yasmin M. Abd El-Aziz ◽  
Ahmed M. Abdeen ◽  
Fatma El Zahraa Ammar Mohamed ◽  
...  
Keyword(s):  
Aluminum Silicate ◽  
Propolis Extract ◽  
Rat Cerebellum ◽  
Histopathological Studies

scholarly journals The protein tyrosine phosphatase RPTPζ/phosphacan is critical for perineuronal net structure

2020 ◽  
Vol 295 (4) ◽  
pp. 955-968
Author(s):  
Geoffrey J. Eill ◽  
Ashis Sinha ◽  
Markus Morawski ◽  
Mariano S. Viapiano ◽  
Russell T. Matthews
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Perineuronal Net ◽  
Protein Tyrosine
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