The haemodynamic effects of long term felodipine therapy in previously untreated essential hypertension

1990 ◽  
Vol 39 (6) ◽  
pp. 539-543
Author(s):  
S. Capewell ◽  
C. G. Wathen ◽  
W. J. Hannan ◽  
A. L. Muir
Keyword(s):  
Essential Hypertension ◽  
Haemodynamic Effects

Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension

1990 ◽  
Vol 8 (12) ◽  
pp. 1129-1136 ◽  
Author(s):  
Per Lund-Johansen ◽  
Per Omvik ◽  
William White ◽  
??ivind Digranes ◽  
Bj??rn Helland ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Haemodynamic Effects

Long-Term Haemodynamic Effects of Amlodipine at Rest and during Exercise in Essential Hypertension

Cardiology ◽  
1992 ◽  
Vol 80 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Per Lund-Johansen ◽  
Per Omvik ◽  
William White ◽  
Øivind Digranes ◽  
Bjørn Helland ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Haemodynamic Effects

scholarly journals Long-term experience of captopril in the treatment of primary (essential) hypertension.

1982 ◽  
Vol 14 (S2) ◽  
pp. 133S-137S ◽  
Author(s):  
BE Karlberg ◽  
J Asplund ◽  
S Wettre ◽  
KP Ohman ◽  
OR Nilsson
Keyword(s):  
Essential Hypertension ◽  
Long Term Experience

ABPM Comparison of the Anti-Hypertensive Profiles of Telmisartan and Enalapril in Patients with Mild-to-Moderate Essential Hypertension

2002 ◽  
Vol 30 (6) ◽  
pp. 543-552 ◽  
Author(s):  
J Amerena ◽  
S Pappas ◽  
J-P Ouellet ◽  
L Williams ◽  
D O'Shaughnessy
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Blood Pressure Monitoring ◽  
Study Drug ◽  
Pressure Control ◽  
Moderate Essential Hypertension ◽  
Open Label ◽  
Night Time ◽  
Once Daily

In this multicentre, prospective, randomized, open-label, blinded-endpoint (PROBE) study, the efficacy of 12 weeks' treatment with once-daily telmisartan 40–80 mg and enalapril 10–20 mg was evaluated using ambulatory blood pressure monitoring (ABPM) in 522 patients with mild-to-moderate essential hypertension. Patients were titrated to the higher dose of study drug at week 6 if mean seated diastolic blood pressure (DBP) was ≥ 90 mmHg. The primary endpoint was the change from baseline in ambulatory DBP in the last 6 h of the 24-h dosing interval after 12 weeks' treatment. Telmisartan and enalapril produced similar reductions from baseline in DBP and systolic blood pressure (SBP) over all ABPM periods evaluated (last 6 h, 24-h, daytime and night-time). Telmisartan produced a significantly greater reduction in mean seated trough DBP, measured unblinded with an automated ABPM device in the clinic, amounting to a difference of −2.02 mmHg ( P < 0.01). A significantly greater proportion of patients achieved a seated diastolic response with telmisartan than enalapril (59% versus 50%; P < 0.05), also measured with the same ABPM device. Both treatments were well tolerated. Compared with telmisartan, enalapril was associated with a higher incidence of cough (8.9% versus 0.8%) and hypotension (3.9% versus 1.1%). Therefore, telmisartan may provide better long-term compliance and, consequently, better blood pressure control than enalapril.

An Unsuccessful Attempt to Treat Hypertension with Acupuncture

1977 ◽  
Vol 05 (01) ◽  
pp. 39-44 ◽  
Author(s):  
K. Sugioka ◽  
W. Mao ◽  
J. Woods ◽  
R. A. Mueller
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Acupuncture Treatment ◽  
Plasma Catecholamines ◽  
Systemic Blood Pressure ◽  
Patient Acceptance ◽  
Unsuccessful Attempt ◽  
Poor Patient ◽  
Beneficial Response

The effectiveness of 5 sets of acupuncture loci in decreasing systemic blood pressure was compared with chlorthalidone and propranolol in patients with essential hypertension. No statistically significant acute or long-term changes in plasma catecholamines, renin activity, or blood pressure and pulse rate were observed as a result of acupuncture treatment. The decrease in blood pressure was significantly less than the observed with propranolol, but not significantly less than produced by chlorthalidone. Because of the poor patient acceptance of acupuncture and in the absence of a beneficial response, we feel acupuncture as employed in this study is of limited value in the management of patients with essential hypertension.

scholarly journals Left ventricular muscle mass and diastolic function in patients with essential hypertension under long-term clonidine monotherapy

1991 ◽  
Vol 14 (2) ◽  
pp. 134-140 ◽  
Author(s):  
Jürgen Hüting ◽  
Veselin Mitrovic ◽  
Jochen Thormann ◽  
Hassan Bahavar ◽  
Martin Schlepper
Keyword(s):  
Essential Hypertension ◽  
Diastolic Function ◽  
Muscle Mass ◽  
Left Ventricular ◽  
Ventricular Muscle ◽  
Left Ventricular Muscle Mass
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