Patterns of exchange induced by mitomycin C in C-bands of human chromosomes. II. High frequency of Y-Y exchange in XYY cells

1982 ◽  
Vol 62 (4) ◽  
pp. 346-348 ◽  
Author(s):  
J. L. Joseph ◽  
J. M. Brasch ◽  
D. R. Smyth
Keyword(s):  
Mitomycin C ◽  
High Frequency ◽  
Human Chromosomes

The Effect of Mitomycin C on Human Chromosomes with G-banding Patterns

1976 ◽  
Vol 17 (2) ◽  
pp. 115
Author(s):  
Tae Sang Tchun ◽  
Sahsook Hahn ◽  
Dong Sik Kim
Keyword(s):  
Mitomycin C ◽  
Human Chromosomes ◽  
Banding Patterns

scholarly journals Involvement of Two Plasmids in the Degradation of Carbaryl by Arthrobacter sp. Strain RC100

1999 ◽  
Vol 65 (3) ◽  
pp. 1015-1019 ◽  
Author(s):  
Masahito Hayatsu ◽  
Motoko Hirano ◽  
Tadahiro Nagata
Keyword(s):  
Carbon Source ◽  
Mitomycin C ◽  
High Frequency ◽  
Sole Carbon Source ◽  
Treated Soil ◽  
Free Strain

ABSTRACT A bacterium capable of utilizing carbaryl (1-naphthylN-methylcarbamate) as the sole carbon source was isolated from carbaryl-treated soil. This bacterium was characterized taxonomically as Arthrobacter and was designated strain RC100. RC100 hydrolyzes the N-methylcarbamate linkage to 1-naphthol, which was further metabolized via salicylate and gentisate. Strain RC100 harbored three plasmids (designated pRC1, pRC2, and pRC3). Mutants unable to degrade carbaryl arose at a high frequency after treating the culture with mitomycin C. All carbaryl-hydrolysis-deficient mutants (Cah−) lacked pRC1, and all 1-naphthol-utilization-deficient mutants (Nat−) lacked pRC2. The plasmid-free strain RC107 grew on gentisate as a carbon source. These two plasmids could be transferred to Cah− mutants or Nat− mutants by conjugation, resulting in the restoration of the Cah and Nah phenotypes.

THE DISTRIBUTION AND LOCALIZATION OF DRUG-INDUCED SECONDARY CONSTRICTIONS IN HUMAN CHROMOSOMES

1972 ◽  
Vol 14 (1) ◽  
pp. 81-93 ◽  
Author(s):  
J. A. Brown ◽  
C. G. Palmer ◽  
P. L. Yu
Keyword(s):  
Dna Synthesis ◽  
Mitomycin C ◽  
Hydroxylamine Hydrochloride ◽  
Human Chromosomes ◽  
Chromosome Identification ◽  
Drug Induced ◽  
Drug Dependent ◽  
Secondary Constrictions

BUdR, mitomycin C and hydroxylamine hydrochloride induce secondary constrictions in particular human chromosomes. The increased frequency of constriction formation in certain chromosomes is time and drug dependent, and correlates well with the timing of DNA synthesis. The frequency at which some of these constrictions can be induced by specific drugs at specific times increases the usefulness of these landmarks in chromosome identification.

scholarly journals Distribution of mitomycin C induced breaks on human chromosomes

Hereditas ◽  
2009 ◽  
Vol 74 (2) ◽  
pp. 273-282 ◽  
Author(s):  
MOHAMED MORAD ◽  
JON JONASSON ◽  
JAN LINDSTEN
Keyword(s):  
Mitomycin C ◽  
Human Chromosomes

scholarly journals Glaucoma in Ectropion Uveae Syndrome: a Case Report and Literature Review

2019 ◽  
Author(s):  
Mohammadmehdi Hatami ◽  
Azadeh Doozandeh ◽  
Mohadeseh Feizi
Keyword(s):  
Intraocular Pressure ◽  
Case Report ◽  
Literature Review ◽  
Mitomycin C ◽  
Axial Length ◽  
High Frequency ◽  
Facial Asymmetry ◽  
Glaucoma Medication ◽  
Shunt Procedure ◽  
Cup To Disc Ratio

Purpose: To report a case of advanced childhood glaucoma secondary to congenital ectropion uveae (CEU). Case Report: The patient was a seven-year-old boy with unilateral glaucoma secondary to CEU and facial asymmetry, mild unilateral ptosis, and proptosis in the left eye. The intraocular pressure (IOP) was 28 mmHg and cup-to-disc ratio was 0.8 in the left eye. After starting glaucoma medication, IOP decreased to 21 mmHg. In view of the uncontrolled IOP with medication and high cup-to-disc ratio and increased axial length of the left eye, mitomycin-C (MMC)-augmented trabeculectomy was planned. Despite sub-tenon MMC injection and bleb needling, the bleb failed after six months, and we had to perform a shunt procedure to control the IOP. Conclusion: Although CEU is rare, ophthalmologists should be familiar with this syndrome because of the high frequency of glaucoma and its challenging management during childhood.

A high frequency of Y-Y chromosome interchanges induced by Mitomycin-C in XYY cells

Pathology ◽  
1983 ◽  
Vol 15 (1) ◽  
pp. 106
Author(s):  
J.L. Joseph ◽  
J.M. Brasch ◽  
D.R. Smyth
Keyword(s):  
Y Chromosome ◽  
Mitomycin C ◽  
High Frequency
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