Cellular injury and carcinogenesis. Evidence for the alkylation of rat liver nucleic acids in vivo by N-nitrosomorpholine

1974 ◽  
Vol 82 (1) ◽  
pp. 1-12 ◽  
Author(s):  
B. W. Stewart ◽  
P. F. Swann ◽  
J. W. Holsman ◽  
P. N. Magee
Keyword(s):  
Nucleic Acids ◽  
Rat Liver ◽  
Cellular Injury

scholarly journals Comparison of the acetylation of proteins and nucleic acids

1970 ◽  
Vol 116 (4) ◽  
pp. 611-615 ◽  
Author(s):  
Woon Ki Paik ◽  
Sangduk Kim
Keyword(s):  
Acetic Acid ◽  
Nucleic Acids ◽  
Sulphuric Acid ◽  
Rat Liver

The possibility of acetylation of nucleic acids was examined. Although protein is actively acetylated with [1-14C]acetic acid in rat liver systems in vivo and in vitro and in a frog liver system in vivo, nucleic acids are not acetylated under these conditions; nucleic acids purified from these sources are without radioactivity. Requirements for acetylation in vitro of protein in rat liver are different from those in frog liver; GSH has no effect in the rat liver system and is inhibitory in the frog liver system. Among various acetylated proteins, proteins insoluble in 0.1m-sulphuric acid have the highest radioactivity.

Effect of X-irradiation on gene expression of rat liver chemokines: in vivo and in vitro studies

2008 ◽  
Vol 46 (01) ◽  
Author(s):  
F Moriconi ◽  
H Christiansen ◽  
H Christiansen ◽  
N Sheikh ◽  
J Dudas ◽  
...  
Keyword(s):  
Gene Expression ◽  
Rat Liver ◽  
In Vitro Studies ◽  
X Irradiation

Chronic, in vivo, PPARα activation prevents lipid overload in rat liver induced by high fat feeding

2009 ◽  
Vol 54 (1) ◽  
Author(s):  
M Wierzbicki ◽  
A Chabowski ◽  
M Żendzian-Piotrowska ◽  
E Harasim ◽  
J Górski
Keyword(s):  
Rat Liver ◽  
High Fat ◽  
Fat Feeding
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